Characterization of the Fc′ Fragment of Immunoglobulin G in Normal Human Urine

Nature ◽  
1969 ◽  
Vol 224 (5222) ◽  
pp. 912-913 ◽  
Author(s):  
M. W. TURNER ◽  
I. BERGGÅRD
Keyword(s):  
Immunoglobulin G ◽  
Human Urine ◽  
Fc Fragment ◽  
Normal Human

Separation and Characterization of Dermatan Sulfate in Normal Human Urine.

1993 ◽  
Vol 16 (4) ◽  
pp. 340-342 ◽  
Author(s):  
Guoning QIU ◽  
Masahiko TANIKAWA ◽  
Hiroshi AKIYAMA ◽  
Toshihiko TOIDA ◽  
Ichiro KOSHIISHI ◽  
...  
Keyword(s):  
Human Urine ◽  
Dermatan Sulfate ◽  
Normal Human

scholarly journals Profiling of lysine-acetylated proteins in human urine

2017 ◽  
Author(s):  
Weiwei Qin ◽  
Zhenhuan Du ◽  
He Huang ◽  
Youhe Gao
Keyword(s):  
Human Urine ◽  
High Resolution Mass Spectrometry ◽  
The Body ◽  
Lysine Acetylation ◽  
Biological Processes ◽  
Post Translational Modification ◽  
Post Translational Modifications ◽  
Normal Human ◽  
Measurable Change

AbstractBiomarker is the measurable change associated with a physiological or pathophysiological process, its nature is change. Contrast to the blood which is under homeostatic controls, urine reflects changes in the body earlier and more sensitive therefore is a better biomarker source. Lysine acetylation is an abundant and highly regulated post-translational modification. It plays a pivotal role in modulating diverse biological processes and is associated with various important diseases. Enrichment or visualization of proteins with specific post-translational modifications provides a method for sampling the urinary proteome and reducing sample complexity. In this study, we used anti-acetyllysine antibody-based immunoaffinity enrichment combined with high-resolution mass spectrometry to profile lysine-acetylated proteins in normal human urine. A total of 629 acetylation sites on 315 proteins were identified, including some very low-abundance proteins. This is the first proteome-wide characterization of lysine acetylation proteins in normal human urine. Our dataset provides a useful resource for the further discovery of the lysine acetylated proteins as biomarker in urine.

scholarly journals CHARACTERIZATION OF ANTIBODIES IN NORMAL HUMAN URINE*

1963 ◽  
Vol 42 (8) ◽  
pp. 1340-1352 ◽  
Author(s):  
Ezio Merler ◽  
Jack S. Remington ◽  
Maxwell Finland ◽  
David Gitlin
Keyword(s):  
Human Urine ◽  
Normal Human
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