Enhancing Effect on Tumour Growth of Humoral Antibodies against Tumour Specific Transplantation Antigens in Tumours induced by Murine Sarcoma Virus (Harvey)

Nature ◽  
1968 ◽  
Vol 220 (5170) ◽  
pp. 928-930 ◽  
Author(s):  
J. BUBENIK ◽  
A. TURANO
Keyword(s):  
Tumour Growth ◽  
Enhancing Effect ◽  
Humoral Antibodies ◽  
Murine Sarcoma Virus ◽  
Sarcoma Virus ◽  
Transplantation Antigens ◽  
Murine Sarcoma

scholarly journals ANTIGENIC PROPERTIES OF MURINE SARCOMA VIRUS-TRANSFORMED BALB/3T3 NONPRODUCER CELLS

1972 ◽  
Vol 135 (3) ◽  
pp. 503-515 ◽  
Author(s):  
John R. Stephenson ◽  
Stuart A. Aaronson
Keyword(s):  
Cell Line ◽  
Leukemia Virus ◽  
Target Cells ◽  
Subsequent Challenge ◽  
Murine Sarcoma Virus ◽  
Sarcoma Virus ◽  
Rauscher Leukemia ◽  
Transplantation Antigens ◽  
Murine Sarcoma ◽  
Rauscher Leukemia Virus

The isolation of clonal lines of murine sarcoma virus-transformed, non-producer BALB/3T3 cells has provided a model system for determining whether RNA tumor virus-transformed cells possess virus-specific transplantation antigens. MSV nonproducer cells (K-234) were clonally derived from an inbred mouse cell line, BALB/3T3. A parallel virus-producing cell line was obtained by infection of the MSV nonproducer cells with Rauscher leukemia virus. K-234 was much more tumorigenic than K-234(R). Preimmunization of syngeneic mice with either K-234(R) or with UV-inactivated Rauscher leukemia virus induced transplantation resistance to subsequent challenge with K-234(R), but not with K-234. In contrast, mice preimmunized with nonproducer cells were not made resistant to subsequent challenge with the homologous cells. Antisera prepared from mice immunized with K-234(R) were specifically cytotoxic and positive by fluorescent antibody staining for K-234(R) target cells, but not to either BALB/3T3 or K-234. The results show that MSV nonproducer cells lack detectable transplantation antigens and suggest that the transplantation resistance to the producing cells is attributable to maturing virus at the cell surface.

Myeloproliferative virus, a cloned murine sarcoma virus with spleen focus-forming properties in adult mice.

1980 ◽  
Vol 33 (2) ◽  
pp. 573-582 ◽  
Author(s):  
W Ostertag ◽  
K Vehmeyer ◽  
B Fagg ◽  
I B Pragnell ◽  
W Paetz ◽  
...  
Keyword(s):  
Adult Mice ◽  
Murine Sarcoma Virus ◽  
Sarcoma Virus ◽  
Murine Sarcoma

Functional organization of the Harvey murine sarcoma virus genome.

1980 ◽  
Vol 35 (1) ◽  
pp. 76-92 ◽  
Author(s):  
E H Chang ◽  
J M Maryak ◽  
C M Wei ◽  
T Y Shih ◽  
R Shober ◽  
...  
Keyword(s):  
Functional Organization ◽  
Virus Genome ◽  
Murine Sarcoma Virus ◽  
Sarcoma Virus ◽  
Murine Sarcoma

Nucleotide sequence analysis of the BALB/c murine sarcoma virus transforming gene.

1985 ◽  
Vol 53 (3) ◽  
pp. 984-987 ◽  
Author(s):  
E P Reddy ◽  
D Lipman ◽  
P R Andersen ◽  
S R Tronick ◽  
S A Aaronson
Keyword(s):  
Sequence Analysis ◽  
Nucleotide Sequence ◽  
Nucleotide Sequence Analysis ◽  
Murine Sarcoma Virus ◽  
Sarcoma Virus ◽  
Murine Sarcoma ◽  
Transforming Gene
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