Post-irradiation Changes in the Deoxyribonucleoprotein Complex in Animal Tissues as revealed by the Action of Heparin

Nature ◽  
1966 ◽  
Vol 212 (5067) ◽  
pp. 1253-1255 ◽  
Author(s):  
M. SKALKA ◽  
J. MATYÁŠOVÁ
2020 ◽  
Vol 22 (2) ◽  
pp. 119-121
Author(s):  
Sharfuddin Mahmud ◽  
Md Shaikhul Islam ◽  
Md Siddiqur Rahman ◽  
Md Rafiul Alam ◽  
Md Asadur Rahman ◽  
...  

“Myiasis” is a parasitic infestation of live human or vertebrate animal tissues or cavities caused by dipterous larvae (maggots) which feed on the host’s dead or living tissue, liquid body substances or ingested food. The case is reported, probably the first in Bangladesh, tracheostomy myiasis. It was caused by infestation with larvae. The patient had undergone tracheostomy 3 years earlier and was a case of ca-larynx. The condition was treated by applying halothane to the tracheostomy wound, which caused spontaneous exit of approximately 30 larvae, easily removed with forceps. Predisposing factors could be: 1. Immuno-compromization due to post-irradiation state of patient; 2. Poor hygiene of tracheostomy tube; 3. Bad smell of wound, which attracts flies; 4. Living in a rural area deprived from necessary health care. Although this is not a lethal disorder, knowledge of the disease is necessary from the preventive, diagnostic and curative standpoint. It is important to proceed with identification of the larvae, distinguishing them from other types of myiasis involving different therapeutic implications. Bangladesh J Otorhinolaryngol; October 2016; 22(2): 119-121


Author(s):  
D. E. Philpott ◽  
W. Sapp ◽  
C. Williams ◽  
Joann Stevenson ◽  
S. Black

The response of spermatogonial cells to X-irradiation is well documented. It has been shown that there is a radiation resistent stem cell (As) which, after irradiation, replenishes the seminiferous epithelium. Most investigations in this area have dealt with radiation dosages of 100R or more. This study was undertaken to observe cellular responses at doses less than 100R of X-irradiation utilizing a system in which the tissue can be used for light and electron microscopy.Brown B6D2F1 mice aged 16 weeks were exposed to X-irradiation (225KeV; 15mA; filter 0.35 Cu; 50-60 R/min). Four mice were irradiated at each dose level between 1 and 100 rads. Testes were removed 3 days post-irradiation, fixed, and embedded. Sections were cut at 2 microns for light microscopy. After staining, surviving spermatogonia were identified and counted in tubule cross sections. The surviving fraction of spermatogonia compared to control, S/S0, was plotted against dose to give the curve shown in Fig. 1.


Author(s):  
Robert C. Rau

Previous work has shown that post-irradiation annealing, at temperatures near 1100°C, produces resolvable dislocation loops in tungsten irradiated to fast (E > 1 MeV) neutron fluences of about 4 x 1019 n/cm2 or greater. To crystallographically characterize these loops, tilting experiments were carried out in the electron microscope on a polycrystalline specimen which had been irradiated to 1.5 × 1021 n/cm2 at reactor ambient temperature (∼ 70°C), and subseouently annealed for 315 hours at 1100°C. This treatment produced large loops averaging 1000 Å in diameter, as shown in the micrographs of Fig. 1. The orientation of this grain was near (001), and tilting was carried out about axes near [100], [10] and [110].


2006 ◽  
Vol 22 (03) ◽  
Author(s):  
Kamal S. Forootan ◽  
Ahmad Maghari ◽  
Lida Saraf
Keyword(s):  

1961 ◽  
Author(s):  
James J. Nickson ◽  
Arvin S. Glicksman
Keyword(s):  

Author(s):  
Lili Pan ◽  
Yu Ma ◽  
Xiaoai Wu ◽  
Huawei Cai ◽  
Feng Qin ◽  
...  

Abstract:: As a group of heterocyclic macrocycle organic natural compounds occurring universally in animal tissues and plants, porphyrins are composed of four modified pyrrole subunits. Porphyrin analogues/derivatives possess multiple biochemical properties because of their unique structures and have been extensively investigated in cancer treatment. Studies have shown that porphyrins and their derivatives have the ability to locate in tumor cells in a variety of human cancers, and these compounds not only exhibit potent therapeutic effects as photodynamic agents but also show promising properties in medicinal imaging, such as MRI, photoacoustic imaging, fluorescence imaging and PET/SPECT imaging. This paper reviews the recent reports of porphyrin derivatives as therapeutic agents used in tumor therapies, such as sonodynamic therapy, photodynamic therapy and radiotherapy, as well as imaging agents for multimodality tumor imaging. The limitations of porphyrin-based compounds in tumor treatments and future prospects are also summarized.


2011 ◽  
Vol 89 (6) ◽  
pp. 453-465 ◽  
Author(s):  
Daryl Codron ◽  
Jacqui Codron ◽  
Matt Sponheimer ◽  
Stefano M. Bernasconi ◽  
Marcus Clauss

The stable carbon isotope composition of animal tissues represents the weighted sum of the variety of food sources eaten. If sources differ in digestibility, tissues may overrepresent intake of more digestible items and faeces may overrepresent less digestible items. We tested this idea using whole blood and faeces of goats ( Capra hircus L., 1758) fed different food mixtures of C3 lucerne ( Medicago sativa L.) and C4 grass ( Themeda triandra Forssk.). Although blood and faecal δ13C values were broadly consistent with diet, results indicate mismatch between consumer and diet isotope compositions: both materials overrepresented the C3 (lucerne) component of diets. Lucerne had lower fibre digestibility than T. triandra, which explains the results for faeces, whereas underrepresentation of dietary C4 in blood is consistent with low protein content of the grass hay. A diet switch experiment revealed an important difference in 13C-incorporation rates across diets, which were slower for grass than lucerne diets, and in fact equilibrium states were not reached for all diets. Although more research is needed to link digestive kinetics with isotope incorporation, these results provide evidence for nonlinear relationships between consumers and their diets, invoking concerns about the conceptual value of “discrimination factors” as the prime currency for contemporary isotope ecology.


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