scholarly journals Effect of Whole-body X-irradiation on 14C-Leucine Incorporation into Proteins of Cell Nuclei of Regenerating Rat Liver

Nature ◽  
1965 ◽  
Vol 205 (4971) ◽  
pp. 615-615 ◽  
Author(s):  
NEDA ŠESTAN
Keyword(s):  
Rat Liver ◽  
Whole Body ◽  
Leucine Incorporation ◽  
Cell Nuclei ◽  
Regenerating Rat Liver ◽  
X Irradiation

scholarly journals Pituitary Effect on Synthesis of Deoxyribonucleic Acid in Regenerating Rat Liver following Whole-body X-irradiation

Nature ◽  
1961 ◽  
Vol 192 (4809) ◽  
pp. 1309-1309 ◽  
Author(s):  
D. M. GOULD ◽  
K. W. FLOYD ◽  
R. W. WHITEHEAD ◽  
J. L. SANDERS
Keyword(s):  
Rat Liver ◽  
Deoxyribonucleic Acid ◽  
Whole Body ◽  
Regenerating Rat Liver ◽  
X Irradiation

Stimulation of cholesterol biosynthesis from acetate in rat liver and adrenals by whole body X-irradiation

1959 ◽  
Vol 196 (6) ◽  
pp. 1231-1237 ◽  
Author(s):  
R. Gordon Gould ◽  
Virginia L. Bell ◽  
Edith H. Lilly
Keyword(s):  
Rat Liver ◽  
Adrenal Glands ◽  
Cholesterol Biosynthesis ◽  
Whole Body ◽  
Hepatic Cholesterol ◽  
Reliable Measure ◽  
Proximate Cause ◽  
Synthetic Rate ◽  
X Irradiation ◽  
Stimulation Of

Whole body x-irradiation resulted in an increased cholesterol biosynthesis in rat liver and adrenal glands, as measured by the rate of incorporation of either acetate-1-C14 or H3OH in intact animals. The effect was significant 24 hours postirradiation but was much larger at 48 hours, and was proportional to dosage over the range 300–2400 r. In liver the increase in rate was about 100%/100 r. Intestine showed no effect and carcass only a slight increase. Mice showed a small increase in hepatic cholesterol biosynthesis but rabbits and guinea pigs no significant change. Rats injected with both acetate-1-C14 and H3OH gave reasonably constant ratios of C14 and H3 in liver and carcass cholesterol in control and irradiated animals, supporting the hypothesis that the use of acetate-1-C14 in whole animals under standard conditions is a reliable measure of cholesterol biosynthetic rate. The proximate cause of the increased rate of cholesterol synthesis is postulated to be the decreased concentration; in liver a decrease of 0.12 mg/gm was correlated with a doubling of the synthetic rate.

scholarly journals Effects of Whole-body X-irradiation on the Incorporation of 3H-orotic acid into Nuclear RNA Fractions of Rat Liver

1969 ◽  
Vol 10 (1) ◽  
pp. 17-24
Author(s):  
Saburo OMATA ◽  
Shogo ICHII ◽  
Nagasumi YAGO ◽  
Shigeru KOBAYASHI
Keyword(s):  
Rat Liver ◽  
Orotic Acid ◽  
Whole Body ◽  
Nuclear Rna ◽  
X Irradiation

scholarly journals Effect of Whole-body X-irradiation on the Microsomal Drug-metabolizing Enzyme System in Rat Liver

1969 ◽  
Vol 10 (1) ◽  
pp. 1-7 ◽  
Author(s):  
Shogo ICHII ◽  
Nagasumi YAGO ◽  
Shigeru KOBAYASHI ◽  
Saburo OMATA
Keyword(s):  
Rat Liver ◽  
Enzyme System ◽  
Whole Body ◽  
Drug Metabolizing Enzyme ◽  
X Irradiation ◽  
Metabolizing Enzyme
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