Taxonomic Relation of Erythrocyte Count, Mean Corpuscular Volume, and Body-Weight in Mammals

Nature ◽  
1965 ◽  
Vol 205 (4970) ◽  
pp. 481-484 ◽  
Author(s):  
PAUL B. DUNAWAY ◽  
LOVELL L. LEWIS
Blood ◽  
1949 ◽  
Vol 4 (11) ◽  
pp. 1256-1263 ◽  
Author(s):  
F. DOUGLAS LAWRASON ◽  
D. C. ELTZHOLTZ ◽  
C. R. SIPE ◽  
P. K. SCHORK

Abstract 1. Six adult swine were given phenylhydrazine hydrochloride orally and intravenously. Hematologic observations, which included periodic bone marrow studies were made before, during, and after the administration of the drug. 2. Five swine responded to the drug in the usual manner with progressive anemia, reticulocytosis, and erythrocytic hyperplasia of the bone marrow. Three animals died between the thirty-ninth and fiftieth day of the experiment after receiving a total dose of 0.30 to 0.35 Gm. per kilogram of body weight. Two swine survived and recovered after receiving a similar dose. 3. One animal died on the fourteenth day of the experiment and exhibited a course which closely resembled that of benzol poisoning. Rapid and progressive granulocytopenia, anemia, and extreme universal hypoplasia of the bone marrow were observed. 4. A direct correlation between the mean corpuscular volume of the red cell and the per cent reticulocytes was found within the limits of 0 to 80 per cent reticulocytosis. With each increment of 10 per cent in the reticulocytes the mean corpuscular volume increased approximately 6.8 cubic microns.


1985 ◽  
Vol 63 (1) ◽  
pp. 58-62 ◽  
Author(s):  
Robert D. Brannon

Eighty-five grizzly bears (Ursus arctos) were captured during 1981 and 1982 in the Alaska Range and in the Arctic National Wildlife Refuge, located in the Brooks Range, Alaska. Blood samples from these bears were examined for erythrocyte count, leukocyte count, hemoglobin, hematocrit, and erythrocyte indices. Erythrocyte count, hemoglobin, hematocrit, and mean corpuscular volume were significantly higher in the first of two samples collected 1 h apart. This difference suggsts a response to stress during the capture by splenic contraction to provide an increased oxygen supply to oxygen depleted muscle tissues, followed by splenic relaxation and decreased blood pressure with expansion of blood plasma volume. Leukocyte count was significantly higher in the second sample. This difference was probably a result of neutrophilia caused by tissue damage from darting and the removal of muscle tissue samples. Alaska Range bears exhibited higher values for all characteristics except mean corpuscular volume and mean corpuscular hemoglobin, indicating that these bears were more stressed by their capture than bears in the Arctic National Wildlife Refuge.


2006 ◽  
Vol 75 (2) ◽  
pp. 203-207 ◽  
Author(s):  
L. Vetešník ◽  
K. Halačka ◽  
V. Lusková ◽  
S. Lusk

Haematological analysis was performed on 27 adult specimens of Carassius auratus irrespective of sex in 2003 and on 32 juveniles of distinguished sex in 2004. In this study we found that the ploidy level affected significantly (p < 0.01) the values of the erythrocyte count, mean corpuscular volume and mean corpuscular haemoglobin. Although we did not prove any significant effect of sex in juvenile diploids of C. auratus on the values of erythrocyte profile, the erythrocyte count, haematocrit value and haemoglobin content value were higher for males than for females. The erythrocyte count decreased significantly (p < 0.01) with increasing ploidy level. The index of haemoglobin content followed the same trend of a decreasing mean value with increasing ploidy level. Mean corpuscular volume and mean corpuscular haemoglobin increased with the increasing ploidy level (p < 0.01). Haematocrit value and mean corpuscular haemoglobin concentration did not significantly differ from the point of view of the ploidy level.


2019 ◽  
Author(s):  
Lloyd Sampa

BACKGROUND Anemia is a worldwide major problem known to affect people throughout the world. It has an adverse effect on both the social and economic development. The worldwide prevalence of anemia is 9% in developed nations. The global estimate indicates that 293.1 million of children under five years, approximately 43%, are anaemic worldwide and 28.5% of these children are found in sub Saharan Africa. In Zambia specifically Kasempa, no documented studies on prevalence have been done. Despite iron supplementation being given to pregnant women and the availability of blood transfusion. The burden of the disease remains high as determined by high mortality and morbidity. This study aims at determining the prevalence of anemia and the associated risk factors among under-five children at Mukinge Mission Hospital in Kasempa District. Knowledge of prevalence and the associated risk factors of anaemia will enhance early detection and timely management. OBJECTIVE 1.To determine the hemoglobin status of anaemia by its severity among anaemic under-five children admitted at Mukinge Mission Hospital. 2.To assess the association of anaemia with Malaria among under-five children admitted at Mukinge Mission Hospital. METHODS This was a retrospective study review of under-five children that were diagnosed and managed of Anemia at Mukinge Missions Hospital, over the period of period of 2015, 2017 and 2018. .Data of the variables of interest was extracted and analyzed using SPSS. RESULTS A sample population of 52 children was included in our study. The majority of the children were females 28 (53.8 %) and 24 (46.2 %) were Males. It was found that moderate and severe anaemia was 17.3% and 82.7 % respectively. Additionally, Majority of the anaemic children (75%) had Normocytic anaemia. The Pearson Chi square test revealed no statistical relationship between the variables; Malaria (p=0.58), Age (P=0.82), Gender (P=0.91). CONCLUSIONS According to our study, 39 (75%) had normal mean corpuscular volume which could suggest chronic diseases and sickle cell anemia. 11 (21.2%) had a low mean corpuscular volume indicating Microcytic anemia which could suggest diseases such as iron deficiency and thalassemia among many other causes. However, we were unable to determine the specific cause of anemia.


Biomolecules ◽  
2021 ◽  
Vol 11 (7) ◽  
pp. 1017
Author(s):  
Thomas Müller ◽  
Lutz Lohse ◽  
Andreas Blodau ◽  
Katja Frommholz

Background: Vitamin D has a steroid- and an anabolic-resembling chemical structure. Vitamin D is essential for many processes in the human body after hydroxylation. Aims of the Study: To investigate the impact of 25-hydroxy-vitamin D plasma concentrations on the blood parameters number of erythrocytes, hematocrit, mean corpuscular hemoglobin and mean corpuscular volume. Methods: Serial assessments were done in 290 patients with multiple sclerosis and repeated after a mean interval of 245 days. A recommendation for vitamin D supplementation was given in case of a concentration lower than 20 ng/mL combined with a prescription of a formulation containing vitamin D but not vitamin K. Results: There was a fall of vitamin D in 119 subjects and a rise in 164, while no change appeared in 7 participants. When vitamin D values went down between both assessments moments, the computed increase of mean corpuscular haemoglobin was significantly lower compared with the rise of mean corpuscular haemoglobin associated with a vitamin D elevation. When vitamin D declined, the computed fall of mean corpuscular volume fall was significantly lower compared with the decrease of mean corpuscular volume, when vitamin D rose. Positive correlations were found between differences of vitamin D and mean corpuscular haemoglobin, respectively mean corpuscular volume. Inverse relations appeared between disparities of vitamin D and erythrocytes, respectively haematocrit. Conclusions: The elevation of vitamin D plasma levels provides enhanced preconditions for a better tissue oxygenation on a cellular level.


Blood ◽  
1981 ◽  
Vol 57 (6) ◽  
pp. 1065-1067 ◽  
Author(s):  
JA Strauchen ◽  
W Alston ◽  
J Anderson ◽  
Z Gustafson ◽  
LF Fajardo

Abstract Because we recently observed two patients with severe diabetic hyperglycemia and spuriously elevated electronically determined hematocrit and mean corpuscular volume (MCV), we investigated the effect of hyperglycemia on two popular automated hematology systems, the Coulter S and Ortho ELT-8. Marked hyperglycemia (blood glucose 800-- 2000 mg/dl) caused consistent overestimation of the electronically determined MCV compared to that derived from a simultaneous spun microhematocrit. The resultant overestimation and underestimation, respectively, of the derived values for hematocrit and mean corpuscular hemoglobin concentration may be clinically misleading. The mechanism of MCV elevation in hyperglycemia appears to be swelling of hyperosmolar glucose “loaded” erythrocytes when diluted into “isotonic” counting medium. This effect is readily circumvented by determination of a spun microhematocrit.


2017 ◽  
Vol 37 (8) ◽  
pp. 1381-1385 ◽  
Author(s):  
Döndü Üsküdar Cansu ◽  
Hava Üsküdar Teke ◽  
Cengiz Korkmaz

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