The Laboratory of the Government Chemist

Nature ◽  
1964 ◽  
Vol 202 (4934) ◽  
pp. 742-743
Author(s):  
QUINTIN HOGG
Keyword(s):  
The Government ◽  
Government Chemist

Chlorinated Hydrocarbon Pesticide Residues in Foodstuffs: Comparison of Methods

1974 ◽  
Vol 57 (1) ◽  
pp. 153-164
Author(s):  
Nigel A Smart ◽  
Alan R C Hill ◽  
Patricia A Roughan
Keyword(s):  
Pesticide Residues ◽  
Comparison Of Methods ◽  
Chlorinated Hydrocarbon ◽  
The Government ◽  
Government Chemist ◽  
A Current

Abstract The AOAC, de Faubert Maunder et al., and Wood methods have been examined for determining BHC, aldrin, heptachlor, DDT, and their major metabolites in milk, butter, cheese, and eggs. Also, the AOAC and the Laboratory of the Government Chemist (UK) methods have been investigated for these pesticides in apples, and both of the latter methods, together with a current EEC method, have been evaluated for measuring the pesticides in potatoes, carrots, and cabbages. Recoveries for these methods were determined by using samples with both added and incurred pesticide residues. There were no gross discrepancies in the results obtained by the different methods, although for certain foodstuffs and in certain situations some methods appeared preferable to others.

scholarly journals Work of the Government Chemist

Nature ◽  
1933 ◽  
Vol 131 (3303) ◽  
pp. 246-246
Keyword(s):  
The Government ◽  
Government Chemist

scholarly journals Almond or Mahaleb? Orthogonal Allergen Analysis During a Live Incident Investigation by ELISA, Molecular Biology, and Protein Mass Spectrometry

2018 ◽  
Vol 101 (1) ◽  
pp. 162-169 ◽  
Author(s):  
Michael J Walker ◽  
Malcolm Burns ◽  
Milena Quaglia ◽  
Gavin Nixon ◽  
Christopher J Hopley ◽  
...  
Keyword(s):  
United Kingdom ◽  
Screening Method ◽  
Peptide Identification ◽  
Cross Reactivity ◽  
Prunus Species ◽  
Protein Mass ◽  
The United Kingdom ◽  
Protein Mass Spectrometry ◽  
The Government ◽  
Government Chemist

Abstract It is now well known that an incident investigated in the United Kingdom in 2015 of cumin alleged to be contaminated with almond, a risk for people with almond allergy, was caused by the Prunus species, Prunus mahaleb. In the United Kingdom, the Government Chemist offers a route of technical appeal from official findings in the food control system. Findings of almond in two official samples, cumin and paprika, which had prompted action to exclude the consignments from the food chain, were so referred. Herein are described the approaches deployed to resolve the analytical issues during the investigation of the incidents. The cross-reactivity of ELISA to Prunus species was confirmed, and although this is useful in screening for the genus, orthogonal techniques are required to identify the species and confirm its presence. Two novel PCR assays were developed: one specific for P. mahaleb and the other a screening method capable of identifying common Prunus DNA. Peptides unique to almond and mahaleb were identified, permitting LC-tandem MS and criteria were developed for peptide identification to forensic standards. This work enables a staged approach to be taken to any future incident thought to involve Prunus species and provides a template for the investigation of similar incidents.

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