Inactivation of Naturally Occurring Variants of Tobacco Mosaic Virus with Nitrous Acid

Nature ◽  
1962 ◽  
Vol 195 (4845) ◽  
pp. 1029-1030 ◽  
Author(s):  
IRVING RAPPAPORT ◽  
S. G. WILDMAN
Nature ◽  
1959 ◽  
Vol 184 (4688) ◽  
pp. BA27-BA29 ◽  
Author(s):  
F. C. BAWDEN

1965 ◽  
Vol 20 (12) ◽  
pp. 1213-1223 ◽  
Author(s):  
H. G. Wittmann

The amino acid sequence of U 2, a naturally occurring strain of tobacco mosaic virus, has been determined. In this communication the experimental details are given for the elucidation of the amino acid sequence within three tryptic peptides with 85 amino acids.


1960 ◽  
Vol 15 (5) ◽  
pp. 298-304 ◽  
Author(s):  
Heinz Schuster

The reaction of nitrous acid with deoxyribonucleic acid (DNA) isolated from different sources was investigated. Contrary to the results found with ribonucleic acid from tobacco mosaic virus, in which all the aminobases are deaminated with about the same velocity, in native DNA the aminobases react with very different reaction velocities. In this case adenine and cytosine react much slower than does the guanine, also the ratios of velocities of the bases vary with the H-ion concentration of the solution. These results confirm the existence of hydrogen bonds involving only the aminogroups of adenine and cytosine in native DNA, whereas in denaturated DNA the aminogroups of all the bases are exposed to nitrous acid deamination.


1965 ◽  
Vol 20 (12) ◽  
pp. 1235-1249 ◽  
Author(s):  
B. Wittmann-Liebold ◽  
J. Jauregui-Adell ◽  
H. G. WlTtmann

The protein structure of temperature-sensitive mutants of tobacco mosaic virus isolated after treatment with nitrous acid has been determined. The results obtained for 15 mutants, presented in this and the preceding paper, are discussed with relation to the spatial structure of the virus rod.


Science ◽  
1951 ◽  
Vol 114 (2966) ◽  
pp. 463-465 ◽  
Author(s):  
S. J. Singer ◽  
J. G. Bald ◽  
S. G Wildman ◽  
R. D. Owen

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