Effect of Sulphonamides on the Phagocytic Activity of the Reticulo-Endothelial System

Nature ◽  
1959 ◽  
Vol 184 (4694) ◽  
pp. 1241-1242 ◽  
Author(s):  
T. NICOL ◽  
I. A. SEWELL
Keyword(s):  
Phagocytic Activity ◽  
Reticulo Endothelial System

scholarly journals Effect of Antibiotics on the Phagocytic Activity of the Reticulo-Endothelial System

Nature ◽  
1958 ◽  
Vol 181 (4624) ◽  
pp. 1662-1662 ◽  
Author(s):  
I. A. SEWELL ◽  
T. NICOL
Keyword(s):  
Phagocytic Activity ◽  
Reticulo Endothelial System

scholarly journals Substances depressing the Phagocytic Activity of the Reticulo-Endothelial System

Nature ◽  
1958 ◽  
Vol 182 (4635) ◽  
pp. 606-606 ◽  
Author(s):  
T. NICOL ◽  
D. L. J. BILBEY
Keyword(s):  
Phagocytic Activity ◽  
Reticulo Endothelial System

THE REDUCTION IN PHAGOCYTIC ACTIVITY OF THE RETICULO-ENDOTHELIAL SYSTEM (RES) PRODUCED BY GENISTEIN

Abstracts ◽  
1977 ◽  
pp. 492
Author(s):  
Juan José Mandoki ◽  
Martha Medina ◽  
Amelia Maldonado ◽  
Cristina Lemini ◽  
Nicandro Mendoza
Keyword(s):  
Phagocytic Activity ◽  
Reticulo Endothelial System

Reticulo-Endothelial System in Relation to Drum Shock

1956 ◽  
Vol 187 (2) ◽  
pp. 263-268 ◽  
Author(s):  
J. M. McKenna ◽  
B. W. Zweifach
Keyword(s):  
Phagocytic Activity ◽  
Traumatic Shock ◽  
Time Dependent ◽  
Physiological Adaptation ◽  
Dramatic Effect ◽  
Subsequent Response ◽  
Colloidal Matter ◽  
Therapeutic Measures ◽  
Reticulo Endothelial System

The administration of colloidal matter, sufficient to blockade the phagocytic activity of the reticulo-endothelial system (RES) in the liver and spleen of rats, has a dramatic effect on the subsequent response to drum trauma. Standardized episodes of trauma in the Noble-Collip drum become more lethal and refractory to therapeutic measures. Resistance to trauma, induced by adaptation to doses of increasing severity, is likewise attenuated by blockade of the RES. The predisposing effects were both dose- and time-dependent. The administration of cortisone in large doses (10–20 mg), an amount shown also to depress RES activity, undermines the capacity of normal rats to withstand traumatic shock, but has no such effect on trauma-resistant animals. It is suggested that the physiological adaptation to trauma may involve an altered relation of the RES to corticosteroids.

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