Critical Temperature for Phase Separation of the Solid Solutions of Rare Gases

Nature ◽  
1956 ◽  
Vol 178 (4530) ◽  
pp. 431-432 ◽  
Author(s):  
G. D. HALSEY ◽  
MARK P. FREEMAN
Keyword(s):  
Phase Separation ◽  
Critical Temperature ◽  
Solid Solutions ◽  
Rare Gases

scholarly journals Taurine suppresses liquid-liquid phase separation of lysozyme protein

2021 ◽  
Author(s):  
Kanae Tsubotani ◽  
Sayuri Maeyama ◽  
Shigeru Murakami ◽  
Stephen W Schaffer ◽  
Takashi Ito
Keyword(s):  
Phase Separation ◽  
Polyethylene Glycol ◽  
Critical Temperature ◽  
Liquid Phase ◽  
Liquid Phase Separation ◽  
Compatible Osmolyte ◽  
Hen Egg ◽  
Liquid Liquid Phase Separation ◽  
In Cells

AbstractTaurine is a compatible osmolyte that infers stability to proteins. Recent studies have revealed that liquid-liquid phase separation (LLPS) of proteins underlie the formation of membraneless organelles in cells. In the present study, we evaluated the role of taurine on LLPS of hen egg lysozyme. We demonstrated that taurine decreases the turbidity of the polyethylene glycol-induced crowding solution of lysozyme. We also demonstrated that taurine attenuates LLPS-dependent cloudiness of lysozyme solution with 0.5 or 1M NaCl at a critical temperature. Moreover, we observed that taurine inhibits LLPS formation of a heteroprotein mix solution of lysozyme and ovalbumin. These data indicate that taurine can modulate the formation of LLPS of proteins.

scholarly journals Stabilizing membrane domains antagonizes n-alcohol anesthesia

2016 ◽  
Author(s):  
B.B. Machta ◽  
E. Grey ◽  
M. Nouri ◽  
N.L.C. McCarthy ◽  
E.M. Gray ◽  
...  
Keyword(s):  
Plasma Membrane ◽  
Phase Separation ◽  
Critical Temperature ◽  
Hydrostatic Pressure ◽  
General Anesthesia ◽  
Membrane Domains ◽  
Strongly Correlated ◽  
Membrane Heterogeneity ◽  
Anesthetic Potency ◽  
Better Than

AbstractDiverse molecules induce general anesthesia with potency strongly correlated both with their hydrophobicity and their effects on certain ion channels. We recently observed that several n-alcohol anesthetics inhibit heterogeneity in plasma membrane derived vesicles by lowering the critical temperature (Tc) for phase separation. Here we exploit conditions that stabilize membrane heterogeneity to further test the correlation between the anesthetic potency of n-alcohols and effects on Tc. First we show that hexadecanol acts oppositely to n-alcohol anesthetics on membrane mixing and antagonizes ethanol induced anesthesia in a tadpole behavioral assay. Second, we show that two previously described ‘intoxication reversers’ raise Tc and counter ethanol’s effects in vesicles, mimicking the findings of previous electrophysiological and behavioral measurements. Third, we find that hydrostatic pressure, long known to reverse anesthesia, also raises Tc in vesicles with a magnitude that counters the effect of butanol at relevant concentrations and pressures. Taken together,these results demonstrate that ΔTc predicts anesthetic potency for n-alcohols better than hydrophobicity in a range of contexts, supporting a mechanistic role for membrane heterogeneity in general anesthesia.

Size Effect in the Phase Separation of Cr–W Solid Solutions

2018 ◽  
Vol 54 (6) ◽  
pp. 546-549 ◽  
Author(s):  
A. V. Shishulin ◽  
V. B. Fedoseev
Keyword(s):  
Phase Separation ◽  
Size Effect ◽  
Solid Solutions

n-Paraffin solid solutions: modification of phase separation with carbon number

1996 ◽  
Vol 255 (4-6) ◽  
pp. 373-377 ◽  
Author(s):  
E.P. Gilbert ◽  
P.A. Reynolds ◽  
A.S. Brown ◽  
J.W. White
Keyword(s):  
Phase Separation ◽  
Solid Solutions ◽  
Carbon Number

Diffusion description of the kinetics of isotopic phase separation of 3He–4He solid solutions

2005 ◽  
Vol 31 (11) ◽  
pp. 951-956 ◽  
Author(s):  
V. N. Grigor’ev ◽  
I. A. Degtyarev ◽  
S. S. Sokolov
Keyword(s):  
Phase Separation ◽  
Solid Solutions ◽  
Kinetics Of

scholarly journals Viscoelastic Phase Patterning in Artificial Protein Hydrogels

2020 ◽  
Author(s):  
Peter Rapp ◽  
Bradley Silverman
Keyword(s):  
Surface Tension ◽  
Phase Separation ◽  
Critical Temperature ◽  
Pattern Formation ◽  
Polymeric Materials ◽  
Size And Shape ◽  
Dynamic Phase ◽  
The Creation ◽  
Dynamic Structures ◽  
Artificial Protein

Viscoelastic forces can affect the dynamics of pattern formation during phase separation in polymeric materials. We programmed an artificial protein hydrogel to undergo viscoelastic phase separation above a critical temperature. Highly dynamic phase patterns that coarsened under the influence of viscoelastic stresses spontaneously emerged in these gels. Local oxidative crosslinking promoted by mild photobleaching could be used to initiate phase separation locally, enabling the creation of non-equilibrium patterns that evolved under the influence of surface tension and viscoelastic stresses to yield dynamic structures of controlled size and shape.

scholarly journals Phase Separation in Garnet Solid Solutions and its Effect on Optical Properties

2013 ◽  
Vol 25 (44) ◽  
pp. 6448-6452 ◽  
Author(s):  
Shakiba Kaveh ◽  
Clément P. Tremblay ◽  
Nurhakimah Norhashim ◽  
Richard J. Curry ◽  
Anthony K. Cheetham
Keyword(s):  
Optical Properties ◽  
Phase Separation ◽  
Solid Solutions
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