Physical Studies of Nucleic Acid: Evidence on the Structure of Deoxyribonucleic Acid from Measurements with Polarized Infra-Red Radiation

Nature ◽  
1951 ◽  
Vol 167 (4254) ◽  
pp. 761-762 ◽  
Author(s):  
MARY J. FRASER ◽  
ROBERT D. B. FRASER
Keyword(s):  
Nucleic Acid ◽  
Deoxyribonucleic Acid ◽  
Infra Red ◽  
Red Radiation

Peptide synthesis in bone marrow: insulin and thyroxin effects

1962 ◽  
Vol 203 (4) ◽  
pp. 693-696 ◽  
Author(s):  
Thomas F. Necheles
Keyword(s):  
Bone Marrow ◽  
Nucleic Acid ◽  
Peptide Synthesis ◽  
Ribonucleic Acid ◽  
Deoxyribonucleic Acid ◽  
Optimum Concentration ◽  
The Other ◽  
Anabolic Effect ◽  
Oxygen Buffer

Myeloid marrow was rapidly removed from femurs of fasting young rabbits, sectioned, and incubated in Krebs-bicarbonate-CO2-oxygen buffer with appropriate C14-labeled precursors. All manipulations were designed to preserve the architecture of the tissue. After 1 hr the protein or nucleic acid-adenine was isolated and purified. Insulin, 0.01 U/ml added in vitro, stimulated histidine-2(ring)-C14 incorporation into protein by 26 ± 1.4%; alkali-treated insulin was inactive. Thyroxin elicited a 49.4 ± 2.1% stimulation at an optimum concentration of 10–7 m. Triiodothyronine, but not diiodothyronine, also had a significant effect. Insulin increased incorporation of carbon from adenosine-8-C14 into adenine of ribonucleic acid and deoxyribonucleic acid. Thyroxin, on the other hand, was without consistent effect on this process. Thyroxin stimulated significantly the incorporation of C14 of glycine-2-C14 into adenine. The possibility that part of the anabolic effect of thyroxin on bone marrow may arise from a stimulus to incorporation of precursors into purines is suggested.

scholarly journals A Strong Infra-Red Radiation from Molecular Nitrogen in the Night Sky

1944 ◽  
Vol 66 (7-8) ◽  
pp. 225-226 ◽  
Author(s):  
Joel Stebbins ◽  
A. E. Whitford ◽  
P. Swings
Keyword(s):  
Molecular Nitrogen ◽  
Infra Red ◽  
Night Sky ◽  
Red Radiation
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