Brain development during childhood and adolescence: a longitudinal MRI study

10.1038/13158 ◽  
1999 ◽  
Vol 2 (10) ◽  
pp. 861-863 ◽  
Author(s):  
Jay N. Giedd ◽  
Jonathan Blumenthal ◽  
Neal O. Jeffries ◽  
F. X. Castellanos ◽  
Hong Liu ◽  
...  
2015 ◽  
Vol 47 (Part_A) ◽  
pp. 52-52
Author(s):  
Budhachandra Khundrakpam ◽  
John Lewis ◽  
Yasser Iturria Medina ◽  
Francois Chouinard‐Decorte ◽  
Alan Evans

Author(s):  
Jay N. Gbedd ◽  
Jonathan Blumenthal ◽  
Neal O. Jeffries ◽  
Jagath C. Rajapakse ◽  
A.Catherine Vaituzis ◽  
...  

NeuroImage ◽  
2016 ◽  
Vol 124 ◽  
pp. 1125-1130 ◽  
Author(s):  
Lindsay Walker ◽  
Lin-Ching Chang ◽  
Amritha Nayak ◽  
M. Okan Irfanoglu ◽  
Kelly N. Botteron ◽  
...  

2001 ◽  
Vol 35 (3) ◽  
pp. 272-281 ◽  
Author(s):  
Judith L. Rapoport ◽  
Xavier F. Castellanos ◽  
Nitin Gogate ◽  
Kristin Janson ◽  
Shawn Kohler ◽  
...  

Objective: The availability of non-invasive brain imaging permits the study of normal and abnormal brain development in childhood and adolescence. This paper summarizes current knowledge of brain abnormalities of two conditions, attention deficit hyperactivity disorder (ADHD) and childhood onset schizophrenia (COS), and illustrates how such findings are bringing clinical and preclinical perspectives closer together. Method: A selected review is presented of the pattern and temporal characteristics of anatomic brain magnetic resonance imaging (MRI) studies in ADHD and COS. These results are discussed in terms of candidate mechanisms suggested by studies in developmental neuroscience. Results: There are consistent, diagnostically specific patterns of brain abnormality for ADHD and COS. Attention deficit hyperactivity disorder is characterized by a slightly smaller (4%) total brain volume (both white and grey matter), less-consistent abnormalities of the basal ganglia and a striking (15%) decrease in posterior inferior cerebellar vermal volume. These changes do not progress with age. In contrast, patients with COS have smaller brain volume due to a 10% decrease in cortical grey volume. Moreover, in COS there is a progressive loss of regional grey volume particularly in frontal and temporal regions during adolescence. Conclusions: In ADHD, the developmental pattern suggests an early non-progressive ‘lesion’ involving neurotrophic factors controlling overall brain growth and selected dopamine circuits. In contrast, in COS, which shows progressive grey matter loss, various candidate processes influencing later synaptic and dendritic pruning are suggested by human post-mortem and developmental animal studies.


2011 ◽  
Vol 26 (9) ◽  
pp. 1691-1697 ◽  
Author(s):  
H. Diana Rosas ◽  
Martin Reuter ◽  
Gheorghe Doros ◽  
Stephanie Y. Lee ◽  
Tyler Triggs ◽  
...  

Author(s):  
Bryce L. Geeraert ◽  
Jess E. Reynolds ◽  
Catherine Lebel

Diffusion magnetic resonance imaging (dMRI) is a versatile tool which can be applied to investigate brain microstructure. This chapter outlines brain development trajectories from infancy to adulthood as described by dMRI. The chapter focuses on white matter development, as dMRI is particularly well suited to describing white matter tissue properties. The chapter also discusses sources of individual variation which are simultaneously fascinating and confounding to research efforts. Next, the chapter discusses links between white matter development and cognition, with specific examples drawn from reading research. Additional techniques which may complement future diffusion-based research are introduced in the chapter’s final section.


2017 ◽  
Vol 46 (7) ◽  
pp. 2308-2314 ◽  
Author(s):  
Xinfeng Yu ◽  
Linglin Yang ◽  
Ruirui Song ◽  
Yerfan Jiaerken ◽  
Jun Yang ◽  
...  

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