Personal resource profiles of individuals with a history of interpersonal trauma and their impact on opioid misuse.

Author(s):  
Jessica Roberts Williams ◽  
Veronica Cole ◽  
Susan S. Girdler ◽  
Martha Grace Cromeens
2012 ◽  
Vol 10 (4) ◽  
pp. 304-311 ◽  
Author(s):  
A. Grattan ◽  
M. D. Sullivan ◽  
K. W. Saunders ◽  
C. I. Campbell ◽  
M. R. Von Korff

Dreaming ◽  
2020 ◽  
Vol 30 (2) ◽  
pp. 107-119 ◽  
Author(s):  
Anika Wiltgen Blanchard ◽  
Katrina Rufino ◽  
Elizabeth Hartwig Rea ◽  
Kieran Paddock ◽  
Michelle A. Patriquin

2018 ◽  
pp. 49-57
Author(s):  
Richard Miech ◽  
Lloyd Johnston ◽  
Patrick M. O’Malley ◽  
Katherine M. Keyes ◽  
Kennon Heard

BACKGROUND AND OBJECTIVE Legitimate opioid use is associated with an increased risk of long-term opioid use and possibly misuse in adults. The objective of this study was to estimate the risk of future opioid misuse among adolescents who have not yet graduated from high school. METHODS Prospective, panel data come from the Monitoring the Future study. The analysis uses a nationally representative sample of 6220 individuals surveyed in school in 12th grade and then followed up through age 23. Analyses are stratified by predicted future opioid misuse as measured in 12th grade on the basis of known risk factors. The main outcome is nonmedical use of a prescription opioid at ages 19 to 23. Predictors include use of a legitimate prescription by 12th grade, as well as baseline history of drug use and baseline attitudes toward illegal drug use. RESULTS Legitimate opioid use before high school graduation is independently associated with a 33% increase in the risk of future opioid misuse after high school. This association is concentrated among individuals who have little to no history of drug use and, as well, strong disapproval of illegal drug use at baseline. CONCLUSIONS Use of prescribed opioids before the 12th grade is independently associated with future opioid misuse among patients with little drug experience and who disapprove of illegal drug use. Clinic-based education and prevention efforts have substantial potential to reduce future opioid misuse among these individuals, who begin opioid use with strong attitudes against illegal drug use.


CJEM ◽  
2019 ◽  
Vol 21 (S1) ◽  
pp. S16-S17
Author(s):  
A. Cragg ◽  
S. Kitchen ◽  
J. Hau ◽  
S. Woo ◽  
C. Liu ◽  
...  

Introduction: Increasing opioid prescribing has been linked to an epidemic of opioid misuse. Our objective was to synthesize available evidence about patient-, prescriber-, medication-, and system-level risk factors for developing opioid misuse from prescribed opioids among patients presenting with pain unrelated to cancer. Our hypothesis was that we would identify risk factors predisposing patients to developing opioid misuse. Methods: We developed a systematic search strategy and applied it to nine electronic reference databases and six clinical trial registries. We hand searched related journals and conference proceedings, the reference lists of included studies, and the top 100 hits on Google. We included studies where a medical professional exposed adults or children to an opioid through a prescription. We excluded studies with over 50% cancer patients, palliative patients, and those with illicit opioid initiation. Two reviewers independently reviewed titles, abstracts, and full texts, and extracted data using standardized forms. We assessed study quality using risk of bias. We synthesized effect sizes of dichotomous risk factors on opioid misuse using inverse variance random-effects meta-analysis, and the inverse variance-weighted mean difference between opioid misusers and non-misusers for continuously measured factors. We conducted an a priori defined subgroup analysis among opioid-naïve patients. Results: Among 9,629 studies, 67 met our inclusion criteria. Among those who had been prescribed outpatient opioids, the following factors were associated with the development of misuse: a prior history of illicit drug use (OR: 4.21, 95% CI: 2.31-7.65), recent benzodiazepine use (OR: 2.57, 95% CI: 1.23-5.38), any mental health diagnosis (OR: 2.45, 95% CI: 1.91-3.15), any short acting (IR) opioid prescription (OR: 2.40, 95% CI: 1.15-5.02), younger age (OR: 2.19, 95%CI: 1.81-2.64), and male sex (OR: 1.23, 95% CI: 1.10-1.36). Among studies limiting their population to opioid-naïve patients, younger age was the most significant risk factor for opioid misuse (OR: 5.42, 95% CI:1.51-19.43). Conclusion: Of the risk factors examined, non-cancer pain patients with a prior history of substance use or mental health diagnoses were at highest risk for prescription opioid misuse. Younger opioid-naïve patients were at highest risk of misuse. Clinicians should consider these risk factors when managing acute pain in the emergency department.


2013 ◽  
Vol 127 (1-3) ◽  
pp. 193-199 ◽  
Author(s):  
Benjamin J. Morasco ◽  
Dennis C. Turk ◽  
Dennis M. Donovan ◽  
Steven K. Dobscha

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