ALS Disability Severity Scale

2005 ◽  
Author(s):  
James Westaby ◽  
Andrea Versenyi ◽  
Robert C. Hausmann
Keyword(s):  
Severity Scale ◽  
Disability Severity

Joint assessment of dependent discrete disease state processes

2015 ◽  
Vol 26 (3) ◽  
pp. 1182-1198 ◽  
Author(s):  
David Engler ◽  
Tanuja Chitnis ◽  
Brian Healy
Keyword(s):  
Multiple Sclerosis ◽  
Ad Hoc ◽  
Simulated Data ◽  
Bayesian Variable Selection ◽  
Dependence Structure ◽  
Severity Scale ◽  
Disease States ◽  
Markovian Processes ◽  
Multiple Sclerosis Patients ◽  
Disability Severity

In multiple sclerosis, the primary clinical measure of disability level is an ordinal score, the expanded disability severity scale score. In relapsing-remitting multiple sclerosis, measures of relapse are additionally of interest. Multiple sclerosis patients are typically assessed with regard to both the expanded disability severity scale and relapse state at each follow-up visit. As both are discrete measures, the two can be viewed as jointly dependent Markov processes. One of the main goals of multiple sclerosis research is to accurately model, over time, both transitions between expanded disability severity scale states and change in relapse state. This objective requires a number of significant modeling decisions, including decisions about whether or not the combination of specific disease states is warranted and assessment of the dependence structure between the two disease processes. Historically, such decisions are often made in an ad hoc manner and are not formally justified. We propose novel use of Bayes factors and Bayesian variable selection in the assessment of jointly dependent Markovian processes in multiple sclerosis. Methods are assessed using both simulated data and data collected from the Partners Multiple Sclerosis Center in Boston, MA.

The measurement of ambulatory impairment in multiple sclerosis

Neurology ◽  
1997 ◽  
Vol 49 (5) ◽  
pp. 1419-1424 ◽  
Author(s):  
S. R. Schwid ◽  
A. D. Goodman ◽  
D. H. Mattson ◽  
C. Mihai ◽  
K. M. Donohoe ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Therapeutic Effects ◽  
Considerable Variability ◽  
Severity Scale ◽  
Precise Information ◽  
Maximal Distance ◽  
Ordinal Scales ◽  
Edss Score ◽  
Disability Severity ◽  
Continuous Measures

The objective of this study was to examine the relationships between continuous measures of ambulatory impairment in MS patients and their ordinal counterparts. Much of the disability caused by MS is due to ambulatory impairment. The Expanded Disability Severity Scale (EDSS) and the Ambulation Index (AI) are ordinal measures of MS severity based largely on the maximal distance subjects can walk (Dmax) and the time to walk 8 m (T8), respectively. At EDSS levels 6.0 to 7.0 and AI levels 3 to 6, scores are defined more by the use of ambulatory aids, rather than by Dmax or T8. We determined Dmax (up to 500 m), T8, the EDSS score, and the AI in 237 ambulatory MS patients. The maximal distance subjects could walk and T8 were strongly related to their ordinal counterparts (Spearman r = 0.65 and 0.91, respectively), but the continuous measures showed considerable variability within EDSS and AI levels that the ordinal scales did not reflect. Most of the variability occurred at EDSS levels 6.0 to 7.0 and AI levels 3 to 6. Because the use of an aid did not clearly predict Dmax or T8, many patients in these ranges had better ambulatory function based on the continuous measures than those with less disability according to the ordinal scales. We found that Dmax and T8 provide more precise information about ambulatory impairment in MS than do the EDSS and AI, allowing better discrimination of differences between patients and potentially greater sensitivity to detect therapeutic effects in clinical trials.

Cognitive strategies application of multiple sclerosis patients

2004 ◽  
Vol 10 (1) ◽  
pp. 67-73 ◽  
Author(s):  
Smadar Birnboim ◽  
Ariel Miller
Keyword(s):  
Multiple Sclerosis ◽  
Daily Living ◽  
Cognitive Rehabilitation ◽  
Cognitive Strategies ◽  
Cognitive Disorders ◽  
Cognitive Tests ◽  
Severity Scale ◽  
Life Tasks ◽  
Multiple Sclerosis Patients ◽  
Disability Severity

When performing a novel task, people need to generate and apply a working strategy. The applicatio n of an appro priate working strategy enables patients with cognitive impairment (C I) to perform tasks efficiently, which in turn makes it easier to meet the challenges of daily life tasks. We investigated the strategy application abilities (SAA) of multiple sclerosis (MS) patients and compared these results with data based on healthy subjects’ performance. Seventy-six patients performed a Strategy A pplication Test (SAT) along with other cognitive tests, and completed depression, fatigue, and activity of daily living (A DL) questionnaires. O ur results indicated that 76% of the MS patients included had impaired SAA, and that this impairment was not correlated with their depression, fatigue, Expanded Disability Severity Scale (EDSS), or A DL. These findings may have important implications for the understanding of the capability of MS patients to cope with nonroutine tasks, as well as for the potential of future implementation of cognitive rehabilitation in improving the SAA of patients with MS or other cognitive disorders.

Substance Dependence Severity Scale

2000 ◽  
Author(s):  
Gloria M. Miele ◽  
Kenneth M. Carpenter ◽  
Melissa Smith Cockerham ◽  
Kristin Dietz Trautman ◽  
Jack Blaine ◽  
...  
Keyword(s):  
Substance Dependence ◽  
Severity Scale

Panic Disorder Severity Scale-Self-Report--2-item Version

2019 ◽  
Author(s):  
Erik Forsell ◽  
Martin Kraepelien ◽  
Kerstin Blom ◽  
Nils Isacsson ◽  
Susanna Jernelöv ◽  
...  
Keyword(s):  
Panic Disorder ◽  
Self Report ◽  
Severity Scale

Idiopathic Hypersomnia Severity Scale

2019 ◽  
Author(s):  
Yves Dauvilliers ◽  
Elisa Evangelista ◽  
Lucie Barateau ◽  
Regis Lopez ◽  
Sofiène Chenini ◽  
...  
Keyword(s):  
Severity Scale ◽  
Idiopathic Hypersomnia

Developmental Disorders in Canada

2020 ◽  
Vol 1 (1) ◽  
Author(s):  
Sarah Palmeter
Keyword(s):  
Public Health ◽  
Developmental Disorders ◽  
Health Agency ◽  
The Public ◽  
Age Of Diagnosis ◽  
High Level ◽  
Project Objectives ◽  
Disability Severity ◽  
Occupational Function ◽  
Improve Health

In the completion of my practicum at the Public Health Agency of Canada (PHAC) this summer, I worked to develop a surveillance knowledge product to support the national surveillance of developmental disorders. This project used Statistics Canada’s 2017 Canadian Survey on Disability to investigate the burden of developmental disorders in Canada. Developmental disorders are conditions with onset in the developmental period. They are associated with developmental deficits and impairments of personal, social, academic, and occupational function. The project objectives are to estimate the prevalence of developmental disorders in Canadians 15 years of age or older, overall and by age and sex, as well as report on the age of diagnosis, disability severity, and disability co-occurrence in those with developmental disorders. The majority of the analysis has been completed and preliminary results completed, which cannot be released prior to PHAC publication. Although not highly prevalent, developmental disorders are associated with a high level of disability in young Canadians. Early detection and interventions have been shown to improve health and social outcomes among affected individuals. Understanding the burden of developmental disorders in Canada is essential to the development of public health policies and services.

scholarly journals The Wheel of Change Moves On: Assessing the Severity of Stalking Behavior

2021 ◽  
pp. 088626052110152
Author(s):  
Ewa B. Stefanska ◽  
Nicholas Longpré ◽  
Rekayla S. Harriman
Keyword(s):  
Social Issue ◽  
Item Response ◽  
Text Messages ◽  
Severity Scale ◽  
Communication Behaviors ◽  
Phone Calls ◽  
Ranking Order ◽  
Minimal Work ◽  
Work Done ◽  
The Continuum

Stalking is a significant social issue. The inconsistency as to what defines stalking has resulted in the creation of different methods to measure the crime. However, there has been minimal work done that assesses the severity of individual stalking behaviors. The aim of the present study was to assess the level of stalking behavior in terms of severity within a randomly selected sample of 924 cases from the database of the National Stalking Helpline. Item response theory analyses were used to assist in developing a scale that displays the ranking order of each stalking behavior. These analyses were also used to examine whether the stalking behavioral items created a single continuum of severity of stalking. Results indicated that 16 stalking behavioral items of the 28 items present in the National Stalking Helpline, best represented the severity of stalking. Unwanted communication behaviors such as text messages and phone calls were located at the lower end of the severity scale, whereas criminal damage and death threats were mapped on the higher end of the continuum. The findings also revealed that the 16 items categorized under 6 factors. The findings of the present study provide many implications for stalking agency professionals and criminal justice responses.

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