BDNF association study with obsessive–compulsive disorder, its clinical characteristics, and response to fluvoxamine-treatment in Iranian patients.

2020 ◽  
Vol 28 (2) ◽  
pp. 216-224 ◽  
Author(s):  
Setareh Abdolhosseinzadeh ◽  
Niyousha Alizadeh ◽  
Jamal Shams ◽  
Sareh Asadi ◽  
Abolhassan Ahmadiani
Keyword(s):  
Association Study ◽  
Obsessive Compulsive Disorder ◽  
Clinical Characteristics ◽  
Obsessive Compulsive ◽  
Compulsive Disorder ◽  
Iranian Patients

Clinical relevance of comorbidity in obsessive compulsive disorder: The Netherlands OCD Association study

2013 ◽  
Vol 150 (3) ◽  
pp. 847-854 ◽  
Author(s):  
Mieke Klein Hofmeijer-Sevink ◽  
Patricia van Oppen ◽  
Harold J. van Megen ◽  
Neeltje M. Batelaan ◽  
Danielle C. Cath ◽  
...  
Keyword(s):  
The Netherlands ◽  
Association Study ◽  
Obsessive Compulsive Disorder ◽  
Clinical Relevance ◽  
Obsessive Compulsive ◽  
Compulsive Disorder

Correlational research on facial and clinical characteristics of adolescents with obsessive-compulsive disorder

2021 ◽  
Author(s):  
Yanrong Wang ◽  
Shaohua Chang ◽  
Xiaomin Ma ◽  
Jiying Li ◽  
Ruixia Zhang ◽  
...  
Keyword(s):  
Obsessive Compulsive Disorder ◽  
Clinical Characteristics ◽  
Healthy Controls ◽  
Obsessive Compulsive ◽  
Lower Lip ◽  
Compulsive Disorder ◽  
Correlational Research ◽  
Nasolabial Angle ◽  
The Difference ◽  
The Relationship

Abstract We examined the relationship between facial morphological features and clinical characteristics of adolescents with obsessive-compulsive disorder (OCD). The enrolled study sample comprised 40 adolescents diagnosed with OCD using the Obsessive Compulsive Inventory Child Version (OCI-CV) and 38 healthy controls (HCs). Facial photos, 21 facial diameters, and nine facial angles were collected using image software. In males, lower lip red height was significantly lower in OCD patients than in HCs (P < 0.05); no significant differences were observed in other facial indicators (all P > 0.05). In females, the nasolabial angle was smaller in OCD patients than in HCs (P < 0.05); no significant differences were observed in other facial indicators (all P > 0.05). The difference in lower lip red height between the OCD group and HC group was positively correlated with mental neutralization symptoms (r = 0.401, P < 0.05). Our findings highlight the relationship between facial and clinical characteristics in OCD patients.

scholarly journals Impacts of Stressful Life Events and Traumatic Experiences on Onset of Obsessive-Compulsive Disorder

2020 ◽  
Vol 11 ◽  
Author(s):  
Keitaro Murayama ◽  
Tomohiro Nakao ◽  
Aikana Ohno ◽  
Sae Tsuruta ◽  
Hirofumi Tomiyama ◽  
...  
Keyword(s):  
Obsessive Compulsive Disorder ◽  
Life Events ◽  
Clinical Characteristics ◽  
Stressful Life Events ◽  
Stressful Life ◽  
Traumatic Experiences ◽  
Obsessive Compulsive ◽  
Compulsive Disorder ◽  
Contamination Fear ◽  
Original Meaning

Not a few patients with obsessive-compulsive disorder (OCD) have experienced events that affected the onset. The onset of OCD is not limited to the original meaning of trauma; rather, traumatic experiences such as unexpected exposure to contaminants or various stressful life events often cause the onset of OCD. It would be useful to understand the experiences surrounding the onset, including stressful life events and traumatic experiences, for comprehension of the pathophysiology of OCD. In the present study, we investigated the onset conditions of 281 patients with OCD and compared clinical characteristics among groups with or without stressful life events including traumatic experiences. As a result, 172 (61.2%) participants had experienced various stressful life events, and 98 (34%) participants had had traumatic experiences before the onset. Furthermore, the participants who had had stressful life events showed more contamination/fear symptoms compared with those without such life events. Meanwhile, the patients who had had specific traumatic experiences showed a tendency toward hoarding obsessions. To comprehend the pathophysiology of OCD, it is important to understand the stressful life events that precede its onset.

scholarly journals Obsessive–compulsive disorder: subclassification based on co-morbidity

2008 ◽  
Vol 39 (9) ◽  
pp. 1491-1501 ◽  
Author(s):  
G. Nestadt ◽  
C. Z. Di ◽  
M. A. Riddle ◽  
M. A. Grados ◽  
B. D. Greenberg ◽  
...  
Keyword(s):  
Anxiety Disorder ◽  
Obsessive Compulsive Disorder ◽  
Clinical Characteristics ◽  
Latent Class ◽  
Age At Onset ◽  
Separation Anxiety Disorder ◽  
Obsessive Compulsive ◽  
Compulsive Disorder ◽  
Co Morbidity ◽  
The Relationship

BackgroundObsessive–compulsive disorder (OCD) is probably an etiologically heterogeneous condition. Many patients manifest other psychiatric syndromes. This study investigated the relationship between OCD and co-morbid conditions to identify subtypes.MethodSeven hundred and six individuals with OCD were assessed in the OCD Collaborative Genetics Study (OCGS). Multi-level latent class analysis was conducted based on the presence of eight co-morbid psychiatric conditions [generalized anxiety disorder (GAD), major depression, panic disorder (PD), separation anxiety disorder (SAD), tics, mania, somatization disorders (Som) and grooming disorders (GrD)]. The relationship of the derived classes to specific clinical characteristics was investigated.ResultsTwo and three classes of OCD syndromes emerge from the analyses. The two-class solution describes lesser and greater co-morbidity classes and the more descriptive three-class solution is characterized by: (1) an OCD simplex class, in which major depressive disorder (MDD) is the most frequent additional disorder; (2) an OCD co-morbid tic-related class, in which tics are prominent and affective syndromes are considerably rarer; and (3) an OCD co-morbid affective-related class in which PD and affective syndromes are highly represented. The OCD co-morbid tic-related class is predominantly male and characterized by high conscientiousness. The OCD co-morbid affective-related class is predominantly female, has a young age at onset, obsessive–compulsive personality disorder (OCPD) features, high scores on the ‘taboo’ factor of OCD symptoms, and low conscientiousness.ConclusionsOCD can be classified into three classes based on co-morbidity. Membership within a class is differentially associated with other clinical characteristics. These classes, if replicated, should have important implications for research and clinical endeavors.

Postpartum obsessive-compulsive disorder: prevalence and clinical characteristics

2009 ◽  
Vol 50 (6) ◽  
pp. 503-509 ◽  
Author(s):  
Carla Fonseca Zambaldi ◽  
Amaury Cantilino ◽  
Ana Carla Montenegro ◽  
Juliana Alencar Paes ◽  
Thiago Lucena César de Albuquerque ◽  
...  
Keyword(s):  
Obsessive Compulsive Disorder ◽  
Clinical Characteristics ◽  
Obsessive Compulsive ◽  
Compulsive Disorder

Association study between obsessive–compulsive disorder and serotonergic candidate genes

2008 ◽  
Vol 32 (3) ◽  
pp. 765-770 ◽  
Author(s):  
Pilar A. Saiz ◽  
Maria P. Garcia-Portilla ◽  
Celso Arango ◽  
Blanca Morales ◽  
Maria-Teresa Bascaran ◽  
...  
Keyword(s):  
Association Study ◽  
Candidate Genes ◽  
Obsessive Compulsive Disorder ◽  
Obsessive Compulsive ◽  
Compulsive Disorder
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