Rhythmic timing in aging adults: On the role of cognitive functioning and structural brain integrity.

2020 ◽  
Vol 35 (8) ◽  
pp. 1184-1200
Author(s):  
Annett Schirmer ◽  
Rafael Romero-Garcia ◽  
Man Hey Chiu ◽  
Nicolas Escoffier ◽  
Trevor B. Penney ◽  
...  
Keyword(s):  
Cognitive Functioning ◽  
Aging Adults ◽  
Structural Brain

scholarly journals The Role of Mobility as a Protective Factor of Cognitive Functioning in Aging Adults

2013 ◽  
Vol 6 (1) ◽  
pp. 63-69 ◽  
Author(s):  
Emily Zhao ◽  
Michael J. Tranovich ◽  
Vonda J. Wright
Keyword(s):  
Cognitive Functioning ◽  
Protective Factor ◽  
Aging Adults

scholarly journals Sex Moderates the Relationship that Number of Professional Fights has with Cognition and Brain Volumes

2020 ◽  
Author(s):  
Lauren L. Bennett ◽  
Steve Stephen ◽  
Charles Bernick ◽  
Guogen Shan ◽  
Sarah J. Banks
Keyword(s):  
Cognitive Functioning ◽  
Cognitive Performance ◽  
Demographic Data ◽  
Moderating Effect ◽  
Analysis Of Covariance ◽  
Brain Volumes ◽  
Regional Brain ◽  
The Relationship ◽  
Structural Brain

ABSTRACTObjectiveIncidence of concussions and report of symptoms are greater amongst women across sports. While structural brain changes and cognitive declines are associated with repetitive head impact (RHI), the role of sex is not well understood. This study aimed to determine if there is a moderating effect of sex on the relationship number of professional fights has with cognitive functioning and regional brain volumes in a cohort of boxers, mixed martial artists, and martial artists.Methods55 women were matched with 55 men based on age, years of education, ethnicity, and fighting style. Cognition was assessed via CNS Vital Signs computerized cognitive battery and supplemental measures. Structural brain scans, demographic data, and number of professional fights (NoPF) were also considered. Matched pairs were compared via analysis of covariance, accounting for total brain volume. Within-subject moderation models were utilized to assess the moderating effect of sex on the relationship between NoPF and brain volumes and cognitive performance.ResultsMen were observed to have poorer performance on measures of psychomotor speed when compared to women. On a series of analyses assessing the role of sex as a moderator of the relationship between NoPF and regional brain volumes/cognitive performance, a significant moderation effect was observed across multiple measures of cognitive functioning, such that men had poorer performance. Differences in numerous regional brain volumes were also observed, such that the relationship between NoPF and brain volumes was steeper amongst men.ConclusionSex was observed to be an important moderator in the relationship between NoPF, aspects of cognitive functioning, and volumes of numerous brain regions, suggesting that sex differences in neuroanatomic and cognitive response to RHI deserve further attention.

scholarly journals Twin-To-Twin Transfusion Syndrome Donor and Recipient and Their Subsequent Cognitive Functioning in Late Childhood as Juvenile Athletes—A Case Study

2021 ◽  
Vol 18 (5) ◽  
pp. 2545
Author(s):  
Ilona Bidzan-Bluma
Keyword(s):  
Cognitive Functioning ◽  
Motor Skills ◽  
Cognitive Functions ◽  
Late Childhood ◽  
Semantic Fluency ◽  
Motor Functioning ◽  
Gross Motor Skills ◽  
History Of

Objective: It is estimated that twin-to-twin transfusion syndrome (TTTS) occurs in 10–15% of monochorionic twin pregnancies. One of the fetuses takes on the role of donor and the other of recipient. The treatment administered involves serial amnioreduction and laser photocoagulation of the communicating blood vessels. After TTTS, children may have deficiencies in psychomotor functioning, in particular in cognitive functions, expressive language, and motor skills. Few scientific reports indicate that twins after TTTS do not demonstrate significant differences in tests which measure intellectual functioning. Methods: The cognitive functioning of twins in the late childhood period was compared using the following tools: an analysis of their medical history, an interview with their parents, and neuropsychological tests allowing the evaluation of their whole profile of cognitive functions. Case Study: Cognitive functioning in the late childhood period was analyzed in a pair of 11-year-old male twins (juvenile athletes), a donor and a recipient, who had developed TTTS syndrome in the prenatal period. Results: Comparison of the cognitive functioning profile of the donor and recipient revealed that children with a history of TTTS develop normally in terms of cognitive and motor functioning in late childhood. A comparative analysis of the donor and recipient was more favorable for the recipient, who had a higher level of general intelligence, visual–motor memory, and semantic fluency. Conclusions: The fact that both the donor and the recipient chose to pursue athletics suggests that gross motor skills are their strongest suit. Playing sports as a method of rehabilitation of cognitive function of children born prematurely after TTTS could contribute to the improvement of cognitive functioning.

scholarly journals The Role of Cognitive Functioning in Medication Adherence of Children and Adolescents with HIV Infection

2008 ◽  
Vol 34 (2) ◽  
pp. 164-175 ◽  
Author(s):  
K. Malee ◽  
P. L. Williams ◽  
G. Montepiedra ◽  
S. Nichols ◽  
P. A. Sirois ◽  
...  
Keyword(s):  
Medication Adherence ◽  
Hiv Infection ◽  
Cognitive Functioning ◽  
Children And Adolescents

scholarly journals Retromer subunit, VPS29, regulates synaptic transmission and is required for endolysosomal function in the aging brain

eLife ◽  
2020 ◽  
Vol 9 ◽  
Author(s):  
Hui Ye ◽  
Shamsideen A Ojelade ◽  
David Li-Kroeger ◽  
Zhongyuan Zuo ◽  
Liping Wang ◽  
...  
Keyword(s):  
Synaptic Transmission ◽  
Protein Complex ◽  
Adult Brain ◽  
Aging Brain ◽  
Gtpase Activating Protein ◽  
Ultrastructural Evidence ◽  
Aging Adults ◽  
And Function ◽  
Brain Homeostasis

Retromer, including Vps35, Vps26, and Vps29, is a protein complex responsible for recycling proteins within the endolysosomal pathway. Although implicated in both Parkinson’s and Alzheimer’s disease, our understanding of retromer function in the adult brain remains limited, in part because Vps35 and Vps26 are essential for development. In Drosophila, we find that Vps29 is dispensable for embryogenesis but required for retromer function in aging adults, including for synaptic transmission, survival, and locomotion. Unexpectedly, in Vps29 mutants, Vps35 and Vps26 proteins are normally expressed and associated, but retromer is mislocalized from neuropil to soma with the Rab7 GTPase. Further, Vps29 phenotypes are suppressed by reducing Rab7 or overexpressing the GTPase activating protein, TBC1D5. With aging, retromer insufficiency triggers progressive endolysosomal dysfunction, with ultrastructural evidence of impaired substrate clearance and lysosomal stress. Our results reveal the role of Vps29 in retromer localization and function, highlighting requirements for brain homeostasis in aging.

scholarly journals Subjective Cognitive Complaints and the Role of Executive Cognitive Functioning in the Working Population: A Case-Control Study

PLoS ONE ◽  
2013 ◽  
Vol 8 (12) ◽  
pp. e83351 ◽  
Author(s):  
Cecilia U. D. Stenfors ◽  
Petter Marklund ◽  
Linda L. Magnusson Hanson ◽  
Töres Theorell ◽  
Lars-Göran Nilsson
Keyword(s):  
Cognitive Functioning ◽  
Case Control Study ◽  
Case Control ◽  
Working Population ◽  
Cognitive Complaints ◽  
Executive Cognitive Functioning ◽  
Control Study ◽  
Subjective Cognitive Complaints
Sign in / Sign up

Export Citation Format

Share Document