Factors influencing sexual performance in male rhesus monkeys.

1977 ◽  
Vol 91 (4) ◽  
pp. 697-710 ◽  
Author(s):  
Charles H. Phoenix
Keyword(s):  
Rhesus Monkeys ◽  
Sexual Performance ◽  
Factors Influencing ◽  
Male Rhesus

OVARIAN HORMONES AND THE SEXUAL BEHAVIOUR OF THE MALE RHESUS MONKEY (MACACA MULATTA) UNDER LABORATORY CONDITIONS

1967 ◽  
Vol 39 (1) ◽  
pp. 81-98 ◽  
Author(s):  
R. P. MICHAEL ◽  
J. HERBERT ◽  
JUDY WELEGALLA
Keyword(s):  
Sexual Behaviour ◽  
Rhesus Monkeys ◽  
Secretory Activity ◽  
Sexual Performance ◽  
Subcutaneous Injections ◽  
Menstrual Cycles ◽  
Female Partners ◽  
Low Levels ◽  
Subsequent Addition ◽  
Male Rhesus

SUMMARY Male sexual behaviour was studied quantitatively by observing pairs of oppositely sexed, adult rhesus monkeys during regular hourly test sessions over 2 yr.; at all other times the animals were housed singly. Rhythmic fluctuations in the mounting behaviour of males occurred in relation to the menstrual cycles of female partners. Two patterns were seen: those with high and low levels of mounting, respectively, in follicular and luteal phases, and those with more isolated maxima near mid-cycle. Ejaculation times were shortest and mounting rates highest near ovulation. Bilateral ovariectomy of females abolished all rhythmic variations in the behaviour of the males, which also stopped ejaculating. Subcutaneous injections of oestradiol into ovariectomized females restored the sexual performance of males, an effect which was partly antagonized by the subsequent addition of progesterone. These findings indicate that sexual behaviour in a male primate is influenced, in some way, by the secretory activity of the female's ovaries.

scholarly journals Sexual Performance Index of Male Rhesus Monkeys

Nature ◽  
1967 ◽  
Vol 214 (5086) ◽  
pp. 425-425 ◽  
Author(s):  
RICHARD P. MICHAEL ◽  
G. SAAYMAN
Keyword(s):  
Performance Index ◽  
Rhesus Monkeys ◽  
Sexual Performance ◽  
Male Rhesus

Evaluation of hippocampus in rhesus monkeys after chronic (1-year) inhalation exposure to marijuana: I. Electron microscopy

1990 ◽  
Vol 48 (3) ◽  
pp. 398-399
Author(s):  
A.M. Andrews ◽  
S.W. Wilson ◽  
A.C. Scallet ◽  
S.F. Ali ◽  
J. Bailey ◽  
...  
Keyword(s):  
Synaptic Vesicles ◽  
Rhesus Monkeys ◽  
Low Dose ◽  
Inhalation Exposure ◽  
Synaptic Cleft ◽  
High Dose ◽  
Withdrawal Time ◽  
Treatment Groups ◽  
Ultrastructural Evidence ◽  
Male Rhesus

Exposure of rhesus monkeys (Macaca mulatta) to marijuana via inhalation or to intravenous delta-9-tetrahydrocannabinol (THC), reportedly caused ultrastructural evidence of increased synaptic width. Chronic marijuana smoke in a single rhesus monkey examined after a six month withdrawal time caused ultrastructure changes in the septal, hippocampal and amygdala regions; the synaptic cleft was widened, electron opaque material was found in the cleft and in the pre- and postsynaptic regions, with some clumping of the synaptic vesicles. The objective of our study was to assess neuropathological alterations produced by chronic inhalation of marijuana smoke.Nineteen male rhesus monkeys, 3-5 years of age and weighing 3-8 kg, were divided into four treatment groups: a) sham control, b) placebo smoke (7 days/ week) c) low dose marijuana (2 times/week with 5 days/week sham) and d) high dose marijuana (7 times/week). A smoke exposure consisted of smoke from one cigarette (2.6% THC) burned down to 10 mm butt length. Smoke was administered via smoke generator (ADL II, Arthur D. Little, Inc. Cambridge, MA) and nose-mouth only masks (local production) equipped with one-way valves.

Experimental delayed radiation necrosis of the brain

1979 ◽  
Vol 51 (5) ◽  
pp. 587-596 ◽  
Author(s):  
Albert N. Martins ◽  
Ralph E. Severance ◽  
James M. Henry ◽  
Thomas F. Doyle
Keyword(s):  
Rhesus Monkeys ◽  
Radiation Necrosis ◽  
Clinical Signs ◽  
Control Group ◽  
Content Type ◽  
Brain Irradiation ◽  
Primate Brain ◽  
High Doses ◽  
The Brain ◽  
Male Rhesus

✓ The authors have designed an experiment to detect a hitherto unrecognized interaction between high doses of the glucocorticoid, dexamethasone, and brain irradiation. Eighteen juvenile male rhesus monkeys received 1800 rads to the whole brain in 8.5 minutes. For 1½ days before and 10½ days after the irradiation, nine animals received approximately 2.9 mg/kg/day of dexamethasone intramuscularly in addition to irradiation, while the remaining nine animals served as the control group and received saline. All animals eventually developed a progressive neurological syndrome, and died of delayed radiation necrosis of the brain. The two groups were compared with regard to latency to onset of clinical signs, survival time, and number, distribution, and location of lesions of radionecrosis. Large doses of dexamethasone did not alter the susceptibility of the primate brain to delayed radiation necrosis. Detailed morphological study of the radionecrotic lesions supports the hypothesis that most, if not all, of the lesions develop as the consequence of injury to blood vessels.

Pituitary response to LRH and TRH stimulation and peripheral steroid hormones in conscious and anaesthetized adult male rhesus monkeys (Macaca mulatta)

1980 ◽  
Vol 93 (3) ◽  
pp. 287-293 ◽  
Author(s):  
E. Jean Wickings ◽  
E. Nieschlag
Keyword(s):  
Adult Male ◽  
Rhesus Monkeys ◽  
Serum Testosterone ◽  
Fold Increase ◽  
Serum Cortisol ◽  
Serum Levels ◽  
Biologically Active ◽  
Similar Response ◽  
Response Curves ◽  
Male Rhesus

Abstract. Adult male rhesus monkeys are aggressive animals and very difficult to handle. Hence experimental manipulations necessarily involve the use of restraint procedures, either chemical or physical, which may influence endocrine functions. Therefore, the effects of ketamine anaesthesia on basal hormone levels and on the pituitary response to LRH and TRH were investigated in 4 adult male rhesus monkeys. Values were compared to those obtained from the same animals restrained in primate chairs for approximately 48 h, a procedure to which they had been accustomed to over the preceding 6 months. Serum cortisol levels under anaesthesia were at all times lower than in conscious monkeys, but increased after 2 h to values twice as high as measured initially. Serum testosterone concentrations were not significantly different on the two occasions, but levels under anaesthesia were slightly higher initially than in the conscious monkeys, and decreased gradually over the 3 h test period. Initial prolactin levels were lower in the anaesthetized monkeys, and increased 2–3-fold after 90 min; values at 3 h were not significantly different from those in conscious monkeys. Intravenous TRH elicited a similar response in prolactin on both occasions, maximum values occurring after 15–30 min and returning to basal levels after 3 h. The maximum values attained and the area under the response curves were higher under anaesthesia. LRH stimulation resulted in a 15- and 30-fold increase in serum levels of biologically active LH, with and without anaesthesia, respectively. Basal levels were not significantly different on the two occasions. The area under the LH response curve was higher in 3 of the 4 monkeys without anaesthesia. The extent to which results in conscious monkeys are affected by stress is difficult to assess. Since neither handling technique allows for the collection of 'true' basal data, it is paramount to standardize and define the conditions under which experiments, and even routine blood sampling, are performed in male rhesus monkeys.

The effects of heroin on prolactin levels in male rhesus monkeys: use of cumulative-dosing procedures

2002 ◽  
Vol 27 (3) ◽  
pp. 319-336 ◽  
Author(s):  
Carrie A. Bowen ◽  
S. Stevens Negus ◽  
Maureen Kelly ◽  
Nancy K. Mello
Keyword(s):  
Rhesus Monkeys ◽  
Male Rhesus

Some effects of putative G-protein biased mu-opioid receptor agonists in male rhesus monkeys

2021 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Jeremy C. Cornelissen ◽  
Bruce E. Blough ◽  
Laura M. Bohn ◽  
S. Stevens Negus ◽  
Matthew L. Banks
Keyword(s):  
G Protein ◽  
Opioid Receptor ◽  
Rhesus Monkeys ◽  
Mu Opioid Receptor ◽  
Mu Opioid ◽  
Receptor Agonists ◽  
Opioid Receptor Agonists ◽  
Male Rhesus
Sign in / Sign up

Export Citation Format

Share Document