Rodent behavior in the presence of barriers: III. Testing of chemical deterrents.

1952 ◽  
Vol 45 (1) ◽  
pp. 103-107 ◽  
Author(s):  
A. W. Bendig ◽  
L. M. Stolurow
2015 ◽  
Vol 38 (9) ◽  
pp. 535-549 ◽  
Author(s):  
João Filipe Oliveira ◽  
Vanessa Morais Sardinha ◽  
Sónia Guerra-Gomes ◽  
Alfonso Araque ◽  
Nuno Sousa
Keyword(s):  

PLoS ONE ◽  
2015 ◽  
Vol 10 (6) ◽  
pp. e0129844 ◽  
Author(s):  
Pau Sunyer ◽  
Ester Boixadera ◽  
Alberto Muñoz ◽  
Raúl Bonal ◽  
Josep Maria Espelta

2011 ◽  
Vol 8 (4) ◽  
pp. 347-352 ◽  
Author(s):  
Daniela Schulz ◽  
Sudeepti Southekal ◽  
Sachin S Junnarkar ◽  
Jean-François Pratte ◽  
Martin L Purschke ◽  
...  

2014 ◽  
Vol 4 (6) ◽  
pp. e399-e399 ◽  
Author(s):  
M Castelhano-Carlos ◽  
P S Costa ◽  
H Russig ◽  
N Sousa
Keyword(s):  

2018 ◽  
Author(s):  
Nicola Solari ◽  
Katalin Sviatkó ◽  
Tamás Laszlovszky ◽  
Panna Hegedüs ◽  
Balázs Hangya

AbstractUnderstanding how the brain controls behavior requires observing and manipulating neural activity in awake behaving animals. Neuronal firing is timed at millisecond precision. Therefore, to decipher temporal coding, it is necessary to monitor and control animal behavior at the same level of temporal accuracy. However, it is technically challenging to deliver sensory stimuli and reinforcers as well as to read the behavioral responses they elicit with millisecond precision. Presently available commercial systems often excel in specific aspects of behavior control, but they do not provide a customizable environment allowing flexible experimental design while maintaining high standards for temporal control necessary for interpreting neuronal activity. Moreover, delay measurements of stimulus and reinforcement delivery are largely unavailable. We combined microcontroller-based behavior control with a sound delivery system for playing complex acoustic stimuli, fast solenoid valves for precisely timed reinforcement delivery and a custom-built sound attenuated chamber using high-end industrial insulation materials. Together this setup provides a physical environment to train head-fixed animals, enables calibrated sound stimuli and precisely timed fluid and air puff presentation as reinforcers. We provide latency measurements for stimulus and reinforcement delivery and an algorithm to perform such measurements on other behavior control systems. Combined with electrophysiology and optogenetic manipulations, the millisecond timing accuracy will help interpret temporally precise neural signals and behavioral changes. Additionally, since software and hardware provided here can be readily customized to achieve a large variety of paradigms, these solutions enable an unusually flexible design of rodent behavioral experiments.


2021 ◽  
Author(s):  
David Kleinfeld ◽  
Martin Deschenes ◽  
Michaël Elbaz ◽  
Amalia Callado Perez ◽  
Conrad Foo ◽  
...  

Vibrissa sensory inputs play a central role in driving rodent behavior. These inputs transit through the sensory trigeminal nuclei, which give rise to the ascending lemniscal and paralemniscal pathways. While lemniscal projections are somatotopically mapped from brain stem to cortex, those of the paralemniscal pathway are more widely distributed. Yet the extent and topography of paralemniscal projections are unknown, along with the potential role of these projections in controlling behavior. Here we used viral tracers to map paralemniscal projections. We find that this pathway broadcasts vibrissa-based sensory signals to brain stem regions that are involved in the regulation of autonomic functions and to forebrain regions that are involved in the expression of emotional reactions. We further provide evidence that GABAergic cells of the Kölliker-Fuse nucleus gate trigeminal sensory input in the paralemniscal pathway via a mechanism of presynaptic or extrasynaptic inhibition.


2020 ◽  
Vol 332 ◽  
pp. 108536 ◽  
Author(s):  
Elsbeth A. van Dam ◽  
Lucas P.J.J. Noldus ◽  
Marcel A.J. van Gerven

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