Drive specificity and learning: the acquisition of a spatial response to food under conditions of water deprivation and food satiation.

1950 ◽  
Vol 40 (2) ◽  
pp. 161-168 ◽  
Author(s):  
Edward L. Walker ◽  
Margaret C. Knotter ◽  
Russell L. Devalois
1976 ◽  
Vol 15 (05) ◽  
pp. 246-247
Author(s):  
S. C. Jain ◽  
G. C. Bhola ◽  
A. Nagaratnam ◽  
M. M. Gupta

SummaryIn the Marinelli chair, a geometry widely used in whole body counting, the lower part of the leg is seen quite inefficiently by the detector. The present paper describes an attempt to modify the standard chair geometry to minimise this limitation. The subject sits crossed-legged in the “Buddha Posture” in the standard chair. Studies with humanoid phantoms and a volunteer sitting in the Buddha posture show that this modification brings marked improvement over the Marinelli chair both from the point of view of sensitivity and uniformity of spatial response.


2015 ◽  
Author(s):  
Phillip Yeoh ◽  
Pierre Bouloux ◽  
Shern Chew ◽  
Bernard Khoo ◽  
Paul Carroll ◽  
...  

1958 ◽  
Vol 4 ◽  
pp. 63 ◽  
Author(s):  
FRANCES L. CLAYTON
Keyword(s):  

2021 ◽  
Vol 7 (22) ◽  
pp. eabf8719
Author(s):  
Yong Han ◽  
Guobin Xia ◽  
Yanlin He ◽  
Yang He ◽  
Monica Farias ◽  
...  

The neural circuitry mechanism that underlies dopaminergic (DA) control of innate feeding behavior is largely uncharacterized. Here, we identified a subpopulation of DA neurons situated in the caudal ventral tegmental area (cVTA) directly innervating DRD1-expressing neurons within the lateral parabrachial nucleus (LPBN). This neural circuit potently suppresses food intake via enhanced satiation response. Notably, this cohort of DAcVTA neurons is activated immediately before the cessation of each feeding bout. Acute inhibition of these DA neurons before bout termination substantially suppresses satiety and prolongs the consummatory feeding. Activation of postsynaptic DRD1LPBN neurons inhibits feeding, whereas genetic deletion of Drd1 within the LPBN causes robust increase in food intake and subsequent weight gain. Furthermore, the DRD1LPBN signaling manifests the central mechanism in methylphenidate-induced hypophagia. In conclusion, our study illuminates a hindbrain DAergic circuit that controls feeding through dynamic regulation in satiety response and meal structure.


Author(s):  
Natalia Mikosch ◽  
Markus Berger ◽  
Elena Huber ◽  
Matthias Finkbeiner

Abstract Purpose The water footprint (WF) method is widely applied to quantify water use along the life cycle of products and organizations and to evaluate the resulting impacts on human health. This study analyzes the cause-effect chains for the human health damage related to the water use on a local scale in the Province Punjab of Pakistan, evaluates their consistency with existing WF models, and provides recommendations for future model development. Method Locally occurring cause-effect chains are analyzed based on site observations in Punjab and a literature review. Then, existing WF models are compared to the findings in the study area including their comprehensiveness (covered cause-effect chains), relevance (contribution of the modeled cause-effect chain to the total health damage), and representativeness (correspondence with the local cause-effect chain). Finally, recommendations for the development of new characterization models describing the local cause-effect chains are provided. Results and discussion The cause-effect chains for the agricultural water deprivation include malnutrition due to reduced food availability and income loss as well as diseases resulting from the use of wastewater for irrigation, out of which only the first one is addressed by existing WF models. The cause-effect chain for the infectious diseases due to domestic water deprivation is associated primarily with the absence of water supply systems, while the linkage to the water consumption of a product system was not identified. The cause-effect chains related to the water pollution include the exposure via agricultural products, fish, and drinking water, all of which are reflected in existing impact assessment models. Including the groundwater compartment may increase the relevance of the model for the study area. Conclusions Most cause-effect chains identified on the local scale are consistent with existing WF models. Modeling currently missing cause-effect chains for the impacts related to the income loss and wastewater usage for irrigation can enhance the assessment of the human health damage in water footprinting.


2007 ◽  
Vol 20 (1) ◽  
pp. 17-28 ◽  
Author(s):  
James P. Hogan ◽  
J. Carol Petherick ◽  
Clive J. C. Phillips

Sheep and cattle are frequently subjected to feed and water deprivation (FWD) for about 12 h before, and then during, transport to reduce digesta load in the gastrointestinal tract. This FWD is marked by weight loss as urine and faeces mainly in the first 24 h but continuing at a reduced rate subsequently. The weight of rumen contents falls although water loss is to some extent masked by saliva inflow. FWD is associated with some stress, particularly when transportation is added. This is indicated by increased levels of plasma cortisol that may be partly responsible for an observed increase in the output of water and N in urine and faeces. Loss of body water induces dehydration that may induce feelings of thirst by effects on the hypothalamus structures through the renin–angiotensin–aldosterone system. There are suggestions that elevated cortisol levels depress angiotensin activity and prevent sensations of thirst in dehydrated animals, but further research in this area is needed. Dehydration coupled with the discharge of Na in urine challenges the maintenance of homeostasis. In FWD, Na excretion in urine is reduced and, with the reduction in digesta load, Na is gradually returned from the digestive tract to the extracellular fluid space. Control of enteropathogenic bacteria by normal rumen microbes is weakened by FWD and resulting infections may threaten animal health and meat safety. Recovery time is required after transport to restore full feed intake and to ensure that adequate glycogen is present in muscle pre-slaughter to maintain meat quality.


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