Experimental studies in affective processes: I. Some effects of cognitive structure and active participation on certain autonomic reactions during and following experimentally induced stress.

1943 ◽  
Vol 33 (4) ◽  
pp. 257-284 ◽  
Author(s):  
E. A. Haggard
Keyword(s):  
Experimental Studies ◽  
Cognitive Structure ◽  
Active Participation ◽  
Induced Stress ◽  
Affective Processes ◽  
Experimentally Induced

scholarly journals Retinas of the Diurnal RodentArvicanthis ansorgeiAre Highly Resistant to Experimentally Induced Stress and Degeneration

2011 ◽  
Vol 52 (12) ◽  
pp. 8686 ◽  
Author(s):  
Domitille L. Boudard ◽  
Niyazi Acar ◽  
Lionel Bretillon ◽  
David Hicks
Keyword(s):  
Induced Stress ◽  
Experimentally Induced

scholarly journals 0275 Exposure to Experimentally Induced Sleep Disturbance Affects the Inflammatory Resolution Pathways in Healthy Humans

SLEEP ◽  
2020 ◽  
Vol 43 (Supplement_1) ◽  
pp. A104-A105
Author(s):  
L C Engert ◽  
M Dubourdeau ◽  
J M Mullington ◽  
M Haack
Keyword(s):  
Sleep Disturbance ◽  
Sleep Disturbances ◽  
Sleep Onset ◽  
Experimental Studies ◽  
Low Grade ◽  
Omega 3 ◽  
Science Center ◽  
Healthy Humans ◽  
Recovery Sleep ◽  
Experimentally Induced

Abstract Introduction Sleep disturbances are assumed to impair health through induction of low-grade systemic inflammation. Experimental studies have shown that such inflammatory upregulation does not normalize even after a couple of nights of recovery sleep. We hypothesized that sleep disturbances do not only affect inflammatory pathways, but also the recently detected inflammatory resolution pathways, which actively terminate inflammation. Mediators of inflammatory resolution mainly derive from omega-3 fatty acids converted to specialized pro-resolving mediators (SPMs), such as resolvins. We investigated SPMs in healthy humans exposed to a novel model of experimental insomnia. Methods Twenty-four individuals (age 18–42 years, 12 women) participated in a study consisting of two 19-day in-hospital protocols (insomnia/control). After three nights of baseline sleep (8h/night, 23:00-07:00), participants in the experimental insomnia condition were exposed to three cycles of three nights of disturbed sleep (delayed sleep-onset, hourly sleep disruption, advanced sleep-offset) followed by one night of 8h-recovery sleep. The protocol ended with three additional nights of recovery sleep. In the control condition, participants had an uninterrupted sleep opportunity (8h/night) across the 19-day protocol. Blood samples were taken at 11:00 at baseline, during experimental insomnia exposure, and after recovery sleep. Several SPMs were measured in plasma using liquid chromatography-tandem mass spectrometry (LC-MS/MS). Data were analyzed using linear mixed models. Results Exposure to experimental insomnia affected several SPMs compared to control sleep, including a decrease of resolvin D4 and E2 concentrations, which was still evident after the third recovery night (p<.05). Conclusion This is the first investigation on the effects of experimentally induced sleep disturbance on inflammatory resolution pathways. The results support that SPMs, particularly resolvin D4 and E2, are decreased by sleep disturbances, and do not normalize after a couple of nights of recovery sleep. Targeting these pathways by pharmacologically increasing SPMs may help to limit inflammatory consequences of sleep disturbances. Support NIH/NINDS R01-NS091177; NIH/National Center for Research Resources UL1-RR02758 and M01-RR01032 to the Harvard Clinical and Translational Science Center.

scholarly journals The effects of experimentally induced stress on false recognition

Memory ◽  
2002 ◽  
Vol 10 (1) ◽  
pp. 1-6 ◽  
Author(s):  
Jessica D. Payne ◽  
Lynn Nadel ◽  
John J.B. Allen ◽  
Kevin G.F. Thomas ◽  
W. Jake Jacobs
Keyword(s):  
False Recognition ◽  
Induced Stress ◽  
Experimentally Induced

Mood and Emotion in Major Depression

2005 ◽  
Vol 14 (3) ◽  
pp. 167-170 ◽  
Author(s):  
Jonathan Rottenberg
Keyword(s):  
Major Depression ◽  
Emotional Reactivity ◽  
Experimental Studies ◽  
Emotional Reactions ◽  
Affective Processes ◽  
Emotion Theory ◽  
Mood Variation

Nothing is more familiar to people than their moods and emotions. Oddly, however, it is not clear how these two kinds of affective processes are related. Intuitively, it makes sense that emotional reactions are stronger when they are congruent with a preexisting mood, an idea reinforced by contemporary emotion theory. Yet empirically, it is uncertain whether moods actually facilitate emotional reactivity to mood-congruent stimuli. One approach to the question of how moods affect emotions is to study mood-disturbed individuals. This review describes recent experimental studies of emotional reactivity conducted with individuals suffering from major depression. Counter to intuitions, major depression is associated with reduced emotional reactivity to sad contexts. A novel account of emotions in depression is advanced to assimilate these findings. Implications for the study of depression and normal mood variation are considered.

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