The specific hunger for sodium chloride in normal and adrenalectomized white rats.

1949 ◽  
Vol 42 (4) ◽  
pp. 242-253 ◽  
Author(s):  
John K. Bare
Keyword(s):  
Sodium Chloride ◽  
White Rats ◽  
Specific Hunger

Effects of Sodium Chloride and Sucrose on Caries Activity in Rats

1971 ◽  
Vol 50 (4) ◽  
pp. 850-853 ◽  
Author(s):  
E.J. Esposito
Keyword(s):  
Drinking Water ◽  
Sodium Chloride ◽  
Caries Activity ◽  
White Rats

Studies of caries activity in caries-susceptible white rats fed sucrose diets and drinking water that contained sodium chloride suggest that sodium chloride may alter the cariogenicity of sucrose.

scholarly journals FINDINGS ON THE CORRECTIVE EFFECT OF MINERAL DILUTED SODIUM CHLORIDE WATER FROM WELL NO. 1 OF OCHAKOV CITY UNDER THE CONDITIONS OF METABOLIC SYNDROME SIMULATION

2021 ◽  
Vol 9 (3) ◽  
Author(s):  
Olena I. Bakholdina ◽  
Oleksiy Ya. Oleshko ◽  
Serhiy H. Gushcha ◽  
Natalya O. Yaroshenko
Keyword(s):  
Metabolic Syndrome ◽  
Sodium Chloride ◽  
Immune Complexes ◽  
The Body ◽  
Circulating Immune Complexes ◽  
Average Weight ◽  
White Rats ◽  
Corrective Effect ◽  
Chloride Water ◽  
Group 2

In the experiment, the effect of low-mineralized mineral diluted sodium chloride water with internal use on the body of animals with experimental metabolic syndrome (MS) was studied. 60 female white rats were divided into three groups of 20 animals each. Group 1 consisted of intact animals; group 2 consisted of animals with MS; group 3 consisted of animals with MS model, which received diluted mineral water (DMW). Objective: to investigate the effect of diluted mineral sodium chloride water from well No. 1 of Ochakov on the state of the organism of rats with the MS model. It was found that the development of the MS model in rats of group 2 was accompanied by a violation of lipid-carbohydrate metabolism (a significant increase in the content of glucose, cholesterol, triglycerides), impaired function of the urinary system, and a significant increase in the body weight of the animals. Signs of the development of endogenous intoxication were revealed – a significant increase in the level of circulating immune complexes and an increase in the level of molecules of average weight. The suppression of detoxification processes was established, as evidenced by a significant increase in the content of creatinine and urea (p < 0.05); that is, there is a cascade of pathological changes from various body systems, which proves that MS is a multiple organ pathology. In rats of the 3rd group, the use of DMW led to a limitation of the development of pathological processes: it was established that the indicators of carbohydrate and lipid metabolism were restored – the level of glucose, cholesterol, and triglyceride significantly decreased compared with the group of rats with uncorrected pathology. Weight gain was also significantly lower. The positive effect on the urine of the educational and excretory function of the kidneys, the restoration of the content of creatinine, urea, the level of average weight molecules, circulating immune complexes, and the activation of phagocytosis processes were determined, which contributed to a decrease in the intoxication load by increasing the detoxification capabilities of the body. The discovered effects indicate the presence of corrects the actions of the DMW in the conditions of experimental MS, which makes it possible to recommend further clinical trials.

OBSERVATIONS UPON THE WITHDRAWAL OF SODIUM CHLORIDE FROM THE DIET IN HYPERTENSIVE AND NORMOTENSIVE INDIVIDUALS

1955 ◽  
Vol 20 (2) ◽  
pp. 173-180 ◽  
Author(s):  
Reata Renwick ◽  
J. S. Robson ◽  
C. P. Stewart
Keyword(s):  
Sodium Chloride

ABOLITION OF MAGNESIUM-INDUCED HYPOCALCAEMIA BY ACUTE THYRO-PARATHYROIDECTOMY IN THE CAT

1970 ◽  
Vol 64 (1) ◽  
pp. 150-158 ◽  
Author(s):  
S. Pors Nielsen
Keyword(s):  
Sodium Chloride ◽  
Flow Rate ◽  
Magnesium Chloride ◽  
Calcium Concentration ◽  
Plasma Calcium ◽  
Magnesium Concentration ◽  
Isotonic Sodium Chloride ◽  
Plasma Calcium Concentration ◽  
High Concentrations ◽  
Plasma Magnesium

ABSTRACT Intravenous infusion of isotonic magnesium chloride into young cats with a resultant mean plasma magnesium concentration of 7.7 meq./100 g protein was followed by a significant lowering of the plasma calcium concentration in 90 minutes. The rate of decrease of plasma calcium is consistent with the hypothesis that calcitonin is released by magnesium in high concentrations. There was no decrease in the plasma calcium concentration in cats of the same weight thyroparathyroidectomized 60 min before an identical magnesium chloride infusion or an infusion of isotonic sodium chloride at the same flow rate. The hypercalciuric effect of magnesium could not account for the hypocalcaemic effect of magnesium. Plasma magnesium concentration during magnesium infusion into cats with an intact thyroid-parathyroid gland complex was slightly, but not significantly higher than in acutely thyroparathyroidectomized cats.

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