Effects of fetal X irradiation on maze-learning ability and motor coordination in albino rats.

1961 ◽  
Vol 54 (2) ◽  
pp. 127-129 ◽  
Author(s):  
Joseph C. Sharp
Keyword(s):  
Motor Coordination ◽  
Maze Learning ◽  
Learning Ability ◽  
Albino Rats ◽  
X Irradiation

scholarly journals Effect of Single and Fractionated X-Irradiation on Maze Learning Ability of Mice

1976 ◽  
Vol 17 (2) ◽  
pp. 82-91 ◽  
Author(s):  
T. AOYAMA ◽  
T. NORIMURA ◽  
T. NAKAMURA ◽  
I. YOSHIKAWA
Keyword(s):  
Maze Learning ◽  
Learning Ability ◽  
X Irradiation

BEHAVIORAL EFFECTS OF PRENATAL DRUG ADMINISTRATION IN THE WHITE RAT

PEDIATRICS ◽  
1961 ◽  
Vol 27 (2) ◽  
pp. 318-324
Author(s):  
Jack Werboff ◽  
Jacques S. Gottlieb ◽  
Joan Havlena ◽  
Thomas J. Word
Keyword(s):  
Open Field ◽  
Field Test ◽  
Open Field Test ◽  
Conditioned Avoidance ◽  
Maze Learning ◽  
Learning Ability ◽  
Albino Rats ◽  
Behavioral Measures ◽  
Conditioned Avoidance Behavior ◽  
Increased Activity

Pregnant albino rats received daily injections of reserpine, iproniazid, 5-HTP, BAS, or sterile water during the second trimester of pregnancy. Offspring of these animals were evaluated on a battery of behavioral measures. There were no uniform effects of the administration of drugs to pregnant mothers. These drugs did have generally adverse effects on maternal mortality and total resorption of the litter. Iproniazid appeared to be most toxic. Significant neonatal mortality occurred in all experimental groups, with 100% mortality of the offspring of mothers receiving iproniazid. Weight of the experimental offspring was less than that of the control offspring, with differences becoming more apparent as the animals grew older. No effect on motor maturation was observed. Activity on the small open field test yielded inconclusive results. However, activity on the inclined plane revealed that offspring of mothers that had been treated with 5-HTP and BAS were significantly faster than control offspring. Increased activity and increased emotionality was observed in the experimental offspring on the open field test. Greater susceptibility to seizures produced by audiogenic stimuli was also found in the experimental animals. In contrast, there were no defects in learning ability in the experimental offspring in either the maze learning or conditioned avoidance behavior situation.

Effects of Prenatal X-Irradiation on Activity, Emotionality, and Maze-Learning Ability in the Rat

1962 ◽  
Vol 16 (4) ◽  
pp. 441 ◽  
Author(s):  
Jack Werboff ◽  
Joan Havlena ◽  
Melvin R. Sikov
Keyword(s):  
Maze Learning ◽  
Learning Ability ◽  
X Irradiation

Effects of prenatal x-irradiation on motor performance in the rat

1961 ◽  
Vol 201 (4) ◽  
pp. 703-706 ◽  
Author(s):  
Jack Werboff ◽  
Irving Goodman ◽  
Joan Havlena ◽  
Melvin R. Sikov
Keyword(s):  
Motor Performance ◽  
Motor Impairment ◽  
Whole Body ◽  
Control Group ◽  
Albino Rats ◽  
Sprague Dawley ◽  
X Irradiation ◽  
Motor Strength ◽  
Low Levels ◽  
Almost All

Gravid albino rats of the Sprague-Dawley strain received either 25, 50, or 100 r whole-body X-radiation on either day 5, 10, 15, or 20 of gestation. Controls were sham-irradiated. Over 500 surviving offspring were evaluated on measures of motor maturation of the upright and righting responses, motor strength, and locomotor learning during the neonatal period. The results indicate that radiation exposure of 100 r on day 15 of gestation retards motor maturation of the upright and righting responses. Almost all of the radiation groups show a decrease in motor strength as compared to the control group with maximum deficits in the groups receiving 50 or 100 r on day 10 or 15 of gestation. On the locomotor learning measure, the results are not consistent, but the group receiving 100 r on day 15 of gestation is maximally affected. These deficits in motor performance are related to observable motor impairment. It is concluded that low levels of radiation received prenatally can have detrimental effects on the development of motor performances in the rat.

The effect of l-carnitine on T-maze learning ability in aged rats

2001 ◽  
Vol 32 (3) ◽  
pp. 245-253 ◽  
Author(s):  
Sandra Lohninger ◽  
Alois Strasser ◽  
Hermann Bubna-Littitz
Keyword(s):  
Maze Learning ◽  
Learning Ability ◽  
Aged Rats
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