Investigation of the Relationship Between Changes in Interpersonal Functioning Over the Course of Therapy and Treatment Outcome

2011 ◽  
Author(s):  
Kathryn Palmer ◽  
Katherine L. Thompson ◽  
Debora A. D'Iuso ◽  
Deborah Schwartzman ◽  
Keith S. Dobson ◽  
...  
2021 ◽  
pp. 1-7
Author(s):  
Alastair J. Flint ◽  
Kathleen S. Bingham ◽  
Nicholas H. Neufeld ◽  
George S. Alexopoulos ◽  
Benoit H. Mulsant ◽  
...  

Abstract Background Little is known about the relationship between psychomotor disturbance (PMD) and treatment outcome of psychotic depression. This study examined the association between PMD and subsequent remission and relapse of treated psychotic depression. Methods Two hundred and sixty-nine men and women aged 18–85 years with an episode of psychotic depression were treated with open-label sertraline plus olanzapine for up to 12 weeks. Participants who remained in remission or near-remission following an 8-week stabilization phase were eligible to participate in a 36-week randomized controlled trial (RCT) that compared the efficacy and tolerability of sertraline plus olanzapine (n = 64) with sertraline plus placebo (n = 62). PMD was measured with the psychiatrist-rated sign-based CORE at acute phase baseline and at RCT baseline. Spearman's correlations and logistic regression analyses were used to analyze the association between CORE total score at acute phase baseline and remission/near-remission and CORE total score at RCT baseline and relapse. Results Higher CORE total score at acute phase baseline was associated with lower frequency of remission/near-remission. Higher CORE total score at RCT baseline was associated with higher frequency of relapse, in the RCT sample as a whole, as well as in each of the two randomized groups. Conclusions PMD is associated with poorer outcome of psychotic depression treated with sertraline plus olanzapine. Future research needs to examine the neurobiology of PMD in psychotic depression in relation to treatment outcome.


2011 ◽  
Vol 19 (1) ◽  
pp. 53-63 ◽  
Author(s):  
Gwenn S. Smith ◽  
Clifford I. Workman ◽  
Elisse Kramer ◽  
Carol R. Hermann ◽  
Rachel Ginsberg ◽  
...  

2010 ◽  
Vol 25 (4) ◽  
pp. 504-517 ◽  
Author(s):  
Megan C. Kearns ◽  
Karen S. Calhoun

This study utilized a cross-sectional design in order to explore the relationship between interpersonal effectiveness, defined as level of assertiveness, social perception, and perceived self-efficacy, and repeated sexual victimization in adolescence and adulthood. In addition, we compared global versus situation-specific measures of interpersonal effectiveness. Results indicated that global measures of interpersonal effectiveness failed to differentiate victim groups, and there were also no group differences in social perception. However, on situation-specific measures, revictimized women were significantly lower than nonvictims on sexual assertiveness and sexual self-efficacy. These results support the hypothesis that interpersonal functioning is related to sexual revictimization and highlight the need to measure interpersonal functioning specifically in sexual situations as it relates to women’s sexual assault history.


2013 ◽  
Vol 27 (3) ◽  
pp. 696-704 ◽  
Author(s):  
Brian L. Odlaug ◽  
Randy Stinchfield ◽  
Ezra Golberstein ◽  
Jon E. Grant

Sign in / Sign up

Export Citation Format

Share Document