The Link Between Anxiety and Neuropsychological Functioning With Depression As a Moderating Factor: A Project Frontier Study

2011 ◽  
Author(s):  
Cortney B. Mauer ◽  
Leigh Johnson ◽  
James R. Hall ◽  
Sid E. O'Bryant
Author(s):  
Vanessa Puetz ◽  
Thomas Günther ◽  
Berrak Kahraman-Lanzerath ◽  
Beate Herpertz-Dahlmann ◽  
Kerstin Konrad

Objectives: Although clear advances have been achieved in the study of early-onset schizophrenia (EOS), little is known to date about premorbid and prodromal neuropsychological functioning in EOS. Method: Here, we report on a case of an adolescent male with EOS who underwent neuropsychological testing before and after illness onset. Results: Marked cognitive deficits in the domains of attention, set-shifting, and verbal memory were present both pre-onset and during the course of schizophrenia, though only deficits in verbal memory persisted after illness-onset and antipsychotic treatment. Conclusion: The findings of this case study suggest that impairments in the verbal memory domain are particularly prominent symptoms of cognitive impairment in prodromal EOS and persist in the course of the disorder, which further demonstrates the difficult clinical situation of adequate schooling opportunities for adolescent patients with EOS.


2010 ◽  
Author(s):  
Kelly L. Konopacki ◽  
Jennifer L. Bruno ◽  
Amy M. Wisniewski ◽  
Shelli R. Kesler ◽  
David N. Rosenthal ◽  
...  

2010 ◽  
Author(s):  
Sarah E. Davis ◽  
Stephanie H. Bader ◽  
Tammy D. Barry

2002 ◽  
Vol 8 (7) ◽  
pp. 873-883 ◽  
Author(s):  
SUSAN F. TAPERT ◽  
ERIC GRANHOLM ◽  
NATHAN G. LEEDY ◽  
SANDRA A. BROWN

This study prospectively examined neuropsychological (NP) functioning associated with adolescent substance use and withdrawal. Participants were youths with histories of substance use disorders (n = 47) and demographically comparable youths with no such lifetime histories (n = 26). They were followed with NP testing and substance involvement interviews at 7 time points spanning 8 years, from ages 16 to 24, on average. After controlling for recent use, age, education, practice effects, and baseline NP functioning, substance use over the 8-year follow-up period significantly predicted performances on tests of memory and attention at Year 8. Additionally, withdrawal symptoms during the follow-up predicted visuospatial and attention scores at Year 8. Findings suggest that use and withdrawal may differentially impact neurocognitive functioning during youth, with heavy use leading to learning, retention, and attentional difficulties, and withdrawal leading to problems with visuospatial functioning. (JINS, 2002, 8, 873–883.)


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