Placing the patient front and center: The patient-centered 'health home' promises to revitalize primary care and provide integrated, cost-effective treatment. How can psychologists get in the door?

2010 ◽  
Author(s):  
Tori DeAngelis
Keyword(s):  
Primary Care ◽  
Effective Treatment ◽  
Cost Effective ◽  
Patient Centered ◽  
Cost Effective Treatment ◽  
Integrated Cost ◽  
Health Home

scholarly journals Cost-effectiveness of antibiotic treatment of uncomplicated urinary tract infection in women: a comparison of four antibiotics

BJGP Open ◽  
2017 ◽  
Vol 1 (3) ◽  
pp. bjgpopen17X101097
Author(s):  
Susannah Sadler ◽  
Michael Holmes ◽  
Shijie Ren ◽  
Stephen Holden ◽  
Swati Jha ◽  
...  
Keyword(s):  
Primary Care ◽  
Urinary Tract ◽  
Cost Effectiveness ◽  
Effective Treatment ◽  
Cost Effective ◽  
Uncomplicated Urinary Tract Infection ◽  
Adult Women ◽  
Effective Treatment Option ◽  
Cost Effective Treatment ◽  
Tract Infections

BackgroundUrinary tract infections (UTIs) are one of the most common reasons for women to attend primary care. There are four different antibiotics currently recommended in England for treatment of uncomplicated UTI but little evidence on their comparative cost-effectiveness.AimTo assess the relative cost-effectiveness of the four antibiotics currently recommended in England for treatment of uncomplicated UTI in adult women.Design & settingA cost-effectiveness model in adult women with signs and symptoms of uncomplicated UTI in primary care in England treated with fosfomycin, nitrofurantoin, pivmecillinam, or trimethoprim.MethodA decision tree economic model of the treatment pathway encompassed up to two rounds of treatment, accounting for different resistance levels. End points included recovery, persistence, pyelonephritis, and/or hospitalisation. Prescription, primary and secondary care treatment, and diagnostic testing costs were aggregated. Cost-effectiveness was assessed as cost per UTI resolved.ResultsTrimethoprim 200 mg twice daily (for 3 or 7 days) was estimated to be the most cost-effective treatment (£70 per UTI resolved) when resistance was <30%. However, if resistance to trimethoprim was ≥30%, fosfomycin 3 g once became more cost-effective; at resistance levels of ≥35% for trimethoprim, both fosfomycin 3 g once and nitrofurantoin 100 mg twice daily for 7 days were shown to be more cost-effective.ConclusionKnowing local resistance levels is key to effective and cost-effective empirical prescribing. Recent estimates of trimethoprim resistance rates are close to 50%, in which case a single 3 g dose of fosfomycin is likely to be the most cost-effective treatment option.

Cost-effective treatment of swine wastes through recovery of energy and nutrients

2017 ◽  
Vol 69 ◽  
pp. 508-517 ◽  
Author(s):  
Adib Amini ◽  
Veronica Aponte-Morales ◽  
Meng Wang ◽  
Merrill Dilbeck ◽  
Ori Lahav ◽  
...  
Keyword(s):  
Effective Treatment ◽  
Cost Effective ◽  
Cost Effective Treatment

scholarly journals Identification of Critical Genes and lncRNAs in Osteolysis after Total Hip Arthroplasty and Osteoarthritis by RNA Sequencing

2021 ◽  
Vol 2021 ◽  
pp. 1-13
Author(s):  
Guang Yang ◽  
Kai Tang ◽  
Li Qiao ◽  
Yixin Li ◽  
Shui Sun
Keyword(s):  
Total Hip Arthroplasty ◽  
Effective Treatment ◽  
Rna Sequencing ◽  
Hip Arthroplasty ◽  
Specific Interaction ◽  
Cost Effective ◽  
Common Complication ◽  
Total Hip ◽  
Cost Effective Treatment ◽  
Coexpression Networks

Total hip arthroplasty (THA) is a cost-effective treatment for osteoarthritis (OA), and osteolysis is a common complication of THA. This study was aimed at exploring the relevant molecular biomarkers for osteolysis after THA. We performed RNA sequence to identify and characterize expressed mRNAs and lncRNAs in OA and osteolysis. Differentially expressed mRNAs (DEmRNAs) and lncRNAs (DElncRNAs) in OA and osteolysis were acquired, as well as shared DEmRNAs/DElncRNAs in OA and osteolysis and osteolysis-specific DEmRNAs/DElncRNAs. Then, shared and osteolysis-specific DElncRNA-DEmRNA coexpression networks were constructed to further investigate the function of DElncRNAs and DEmRNAs in OA and osteolysis. In total, 343 DEmRNAs and 25 DElncRNAs in OA, 908 DEmRNAs and 107 DElncRNAs in osteolysis, and 406 DEmRNAs and 46 DElncRNAs between OA and osteolysis were acquired. A total of 136 shared DEmRNAs and 9 shared DElncRNAs in OA and osteolysis and 736 osteolysis-specific DEmRNAs and 103 osteolysis-specific DElncRNAs were acquired. Then, 128 shared DElncRNA-DEmRNA coexpression pairs and 522 osteolysis-specific DElncRNA-DEmRNA coexpression pairs were identified. The present study highlighted the roles of four interaction pairs, including two shared lncRNA-mRNA interaction pairs in OA and osteolysis (AC111000.4 and AC016831.6), which may function in the immune process of OA and osteolysis by regulating CD8A and CD8B, respectively, and two osteolysis-specific interaction pairs (AC090607.4-FOXO3 and TAL1-ABALON), which may play an important role in osteoclastogenesis.

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