Depression, Illness Severity, and Health Care Utilization in Cystic Fibrosis

2012 ◽  
Author(s):  
Carolyn J. Snell ◽  
Georgina Garcia
Keyword(s):  
Health Care ◽  
Cystic Fibrosis ◽  
Health Care Utilization ◽  
Illness Severity ◽  
Care Utilization

Sexual and Reproductive Health Care Utilization and Preferences of Young Women With Cystic Fibrosis

2017 ◽  
Vol 60 (2) ◽  
pp. S35-S36
Author(s):  
Traci M. Kazmerski ◽  
Sonya Borrero ◽  
Gregory Sawicki ◽  
Kelley A. Jones ◽  
Kaleab Z. Abebe ◽  
...  
Keyword(s):  
Health Care ◽  
Cystic Fibrosis ◽  
Reproductive Health ◽  
Health Care Utilization ◽  
Young Women ◽  
Sexual And Reproductive Health ◽  
Care Utilization ◽  
Reproductive Health Care

scholarly journals Practitioner Due Diligence: Real-World Lumacaftor/Ivacaftor Use

2020 ◽  
Vol 25 (5) ◽  
pp. 431-436
Author(s):  
Emily M. Stephan ◽  
Christopher J. Nemastil ◽  
Ann Salvator ◽  
Susan Gemma ◽  
Clarissa J. Dilaveris ◽  
...  
Keyword(s):  
Health Care ◽  
Body Mass Index ◽  
Cystic Fibrosis ◽  
Health Care Utilization ◽  
Body Mass ◽  
Real World ◽  
Forced Expiratory Volume ◽  
Emergency Department Visits ◽  
Care Utilization ◽  
The Impact

OBJECTIVE Previous trials evaluated the efficacy of lumacaftor/ivacaftor in Phe508del homozygotes. These trials are limited by manufacturer sponsorship and were conducted under strict protocol. Additionally, this therapy is costly and does not allow for reduction in daily cystic fibrosis therapies. This study assessed the efficacy of lumacaftor/ivacaftor therapy and its effect on health care utilization in a real-world setting. METHODS Retrospective chart review comparing the first 12 months of therapy to the 24 months prior was conducted to evaluate the impact of lumacaftor/ivacaftor on pulmonary function following a streamlined process for therapy introduction. The impact on body mass index and healthcare utilization were also evaluated. The following measurements were assessed: percent predicted forced expiratory volume in 1 second, body mass index and z-scores, number of admissions, length of stay, number of emergency department visits. RESULTS Mean ppFEV1 was improved for the first 12 months on lumacaftor/ivacaftor treatment when compared with the 24 months prior: 78.8 (95% CI: 72.6, 84.9) vs 76.2 (95% CI: 70.1, 82.3) (p = 0.03). Body mass index significantly improved (patients ≥20 years), but improvement in BMI z-score (patients <20 years) was not significant. Number of admissions and LOS were significantly decreased, but ED visits were not. CONCLUSIONS Lumacaftor/ivacaftor is effective for improving ppFEV1 and BMI and for reducing health care utilization. However, this small reduction does not overcome the financial cost of treatment. Long-term outcomes and use must be studied to determine the overall effect of this therapy on cystic fibrosis interventions and their costs.

scholarly journals Sexual and reproductive health care utilization and preferences reported by young women with cystic fibrosis

2018 ◽  
Vol 17 (1) ◽  
pp. 64-70 ◽  
Author(s):  
Traci M. Kazmerski ◽  
Gregory S. Sawicki ◽  
Elizabeth Miller ◽  
Kelley A. Jones ◽  
Kaleab Z. Abebe ◽  
...  
Keyword(s):  
Health Care ◽  
Cystic Fibrosis ◽  
Reproductive Health ◽  
Health Care Utilization ◽  
Young Women ◽  
Sexual And Reproductive Health ◽  
Care Utilization ◽  
Reproductive Health Care
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