Behavioral epigenetics: genomic imprinting affects cognition

2011 ◽  
Author(s):  
Valter Tucci
Keyword(s):  
Genomic Imprinting

The Inclusive Fitness Dynamics of Genomic Imprinting

Selection ◽  
2002 ◽  
Vol 2 (1-2) ◽  
pp. 103-118 ◽  
Author(s):  
J. M. Greenwood-Lee ◽  
P. D. Taylor ◽  
D. Haig
Keyword(s):  
Genomic Imprinting ◽  
Inclusive Fitness

Methylated DNA Sequences in Genomic Imprinting

2000 ◽  
Vol 10 (3-4) ◽  
pp. 18 ◽  
Author(s):  
Jeffrey R. Mann ◽  
Piroska E. Szabo ◽  
Michael R. Reed ◽  
Judith Singer-Sam
Keyword(s):  
Genomic Imprinting ◽  
Dna Sequences ◽  
Methylated Dna

From Genomic Imprinting to Developmental Physiology: Identifying Stepping Stones

2004 ◽  
Vol 2 (3) ◽  
pp. 233-242 ◽  
Author(s):  
Bernard Dan ◽  
Stewart Boyd ◽  
Guy Cheron
Keyword(s):  
Genomic Imprinting ◽  
Stepping Stones ◽  
Developmental Physiology

scholarly journals The Evolution of Genomic Imprinting

Genetics ◽  
1996 ◽  
Vol 144 (3) ◽  
pp. 1283-1295 ◽  
Author(s):  
Atsushi Mochizuki ◽  
Yasuhiko Takeda ◽  
Yoh Iwasa
Keyword(s):  
Growth Factor ◽  
Genomic Imprinting ◽  
Parental Origin ◽  
Coding Region ◽  
Placental Development ◽  
Genetic Conflict ◽  
Multiple Partners ◽  
Zygotic Gene ◽  
Mammalian Genes ◽  
Maternal Resources

Abstract In some mammalian genes, the paternally and maternally derived alleles are expressed differently: this phenomenon is called genomic imprinting. Here we study the evolution of imprinting using multivariate quantitative genetic models to examine the feasibility of the genetic conflict hypothesis. This hypothesis explains the observed imprinting patterns as an evolutionary outcome of the conflict between the paternal and maternal alleles. We consider the expression of a zygotic gene, which codes for an embryonic growth factor affecting the amount of maternal resources obtained through the placenta. We assume that the gene produces the growth factor in two different amounts depending on its parental origin. We show that genomic imprinting evolves easily if females have some probability of multiple partners. This is in conflict with the observation that not all genes controlling placental development are imprinted and that imprinting in some genes is not conserved between mice and humans. We show however that deleterious mutations in the coding region of the gene create selection against imprinting.

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