Risk and resilience in high-risk samples: How to promote positive outcomes for young children

2010 ◽  
Author(s):  
Margo Candelaria ◽  
Kathy Katz ◽  
Anna Quigg ◽  
Sarah Oberlander ◽  
Margo Candelaria
Keyword(s):  
High Risk ◽  
Young Children ◽  
Positive Outcomes ◽  
Risk And Resilience

Poster #S151 NEUROCOGNITIVE PROFILES IN 7-YEAR-OLD OFFSPRING OF PARENTS WITH SCHIZOPHRENIA OR BIPOLAR DISORDER. PART OF THE HIGH RISK AND RESILIENCE STUDY – VIA 7

2014 ◽  
Vol 153 ◽  
pp. S143-S144
Author(s):  
Nicoline Hemager ◽  
Jens Richardt Møllegaard Jepsen ◽  
Anne Amalie Elgaard Thorup ◽  
Camilla Austa Jerlang Christiani ◽  
Aja Neergaard Greve ◽  
...  
Keyword(s):  
Bipolar Disorder ◽  
High Risk ◽  
Risk And Resilience ◽  
Neurocognitive Profiles

scholarly journals Early Development of Locomotor Patterns and Motor Control in Very Young Children at High Risk of Cerebral Palsy, a Longitudinal Case Series

2021 ◽  
Vol 15 ◽  
Author(s):  
Annike Bekius ◽  
Margit M. Bach ◽  
Laura A. van de Pol ◽  
Jaap Harlaar ◽  
Andreas Daffertshofer ◽  
...  
Keyword(s):  
Cerebral Palsy ◽  
High Risk ◽  
Young Children ◽  
Early Development ◽  
Muscle Activation ◽  
Brain Lesions ◽  
Very Young Children ◽  
Gait Parameters ◽  
Locomotor Patterns ◽  
Over Time

The first years of life might be critical for encouraging independent walking in children with cerebral palsy (CP). We sought to identify mechanisms that may underlie the impaired development of walking in three young children with early brain lesions, at high risk of CP, via comprehensive instrumented longitudinal assessments of locomotor patterns and muscle activation during walking. We followed three children (P1–P3) with early brain lesions, at high risk of CP, during five consecutive gait analysis sessions covering a period of 1 to 2 years, starting before the onset of independent walking, and including the session during the first independent steps. In the course of the study, P1 did not develop CP, P2 was diagnosed with unilateral and P3 with bilateral CP. We monitored the early development of locomotor patterns over time via spatiotemporal gait parameters, intersegmental coordination (estimated via principal component analysis), electromyography activity, and muscle synergies (determined from 11 bilateral muscles via nonnegative matrix factorization). P1 and P2 started to walk independently at the corrected age of 14 and 22 months, respectively. In both of them, spatiotemporal gait parameters, intersegmental coordination, muscle activation patterns, and muscle synergy structure changed from supported to independent walking, although to a lesser extent when unilateral CP was diagnosed (P2), especially for the most affected leg. The child with bilateral CP (P3) did not develop independent walking, and all the parameters did not change over time. Our exploratory longitudinal study revealed differences in maturation of locomotor patterns between children with divergent developmental trajectories. We succeeded in identifying mechanisms that may underlie impaired walking development in very young children at high risk of CP. When verified in larger sample sizes, our approach may be considered a means to improve prognosis and to pinpoint possible targets for early intervention.

scholarly journals Resistance to temptation in toddlers at genetic risk for autism spectrum disorder

Autism ◽  
2018 ◽  
Vol 23 (4) ◽  
pp. 1018-1027
Author(s):  
Susan B Campbell ◽  
Jessie B Northrup ◽  
Amy B Tavares
Keyword(s):  
Autism Spectrum Disorder ◽  
High Risk ◽  
Young Children ◽  
Self Regulation ◽  
Children With Autism ◽  
Autism Spectrum ◽  
Low Risk ◽  
Spectrum Disorder ◽  
Typically Developing ◽  
High Risk Children

Children with autism spectrum disorder often demonstrate difficulties with self-regulation, although studies of this construct in young children with autism spectrum disorder are limited. In this study, developmental changes were examined using a measure of self-regulation appropriate for young children, resistance to temptation. At 22, 28, and 34 months, toddlers with an older sibling with autism spectrum disorder (high risk) and toddlers with typically developing older siblings (low risk) were presented with an appealing toy and instructed not to touch it. Observers coded whether or not children touched the toy and the strategies they used to resist touching it. At 36 months, children were assessed for autism spectrum disorder, yielding three groups: high risk children with autism spectrum disorder, high risk children without autism spectrum disorder, and low risk children. At 22 months, most children, regardless of group, touched the forbidden toy; at 28 and 34 months, many high risk children without autism spectrum disorder and low risk children resisted the temptation to touch the toy, whereas most of the children with autism spectrum disorder did not. Differences in delay strategies were also evident. Some, but not all group differences, were accounted for by differences in language ability. Results highlight one early index of impulse control that differentiates children with emerging autism spectrum disorder from age-mates prior to the third birthday.

Bacteremia: Occult or Nonoccult?

PEDIATRICS ◽  
1988 ◽  
Vol 81 (2) ◽  
pp. 332-332
Author(s):  
LORRY G. RUBIN
Keyword(s):  
High Risk ◽  
Young Children ◽  
Antibiotic Therapy ◽  
Small Proportion ◽  
Antigen Detection ◽  
Bacterial Antigen ◽  
Ambulatory Visit ◽  
Focus Of Infection

In Reply.— In our study we sought to evaluate the efficacy of bacterial antigen detection in highly febrile young children with occult or "unsuspected" bacteremia, ie, patients whose presentations did not necessarily mandate IV antibiotic therapy, but in whom parenteral a antibiotic therapy would be indicated if bacteremia could be reliably diagnosed at the initial ambulatory visit. The patients referred to by Dr Mauro, those with no focus of infection, constitute a small proportion of occult bacteremic patients (although a group at relatively high risk for bacteremia).

scholarly journals Impact of Social Distancing and Travel Restrictions on Non–Coronavirus Disease 2019 (Non–COVID-19) Respiratory Hospital Admissions in Young Children in Rural Alaska

2020 ◽  
Author(s):  
Leisha D Nolen ◽  
Sara Seeman ◽  
Dana Bruden ◽  
Joe Klejka ◽  
Chris Desnoyers ◽  
...  
Keyword(s):  
High Risk ◽  
Young Children ◽  
Hospital Admissions ◽  
High Risk Population ◽  
Respiratory Illnesses ◽  
Social Distancing ◽  
The Past ◽  
Secondary Benefits ◽  
Rural Alaska ◽  
Travel Restrictions

Abstract Hospitalizations due to non-coronavirus disease 2019 (non-COVID-19) respiratory illnesses decreased dramatically after social distancing was implemented in a high-risk population in rural Alaska; an unprecedented decline compared to the past 10 respiratory seasons. This demonstrates the potential secondary benefits of implementing social distancing and travel restrictions on respiratory illnesses.

scholarly journals Young children with medulloblastoma: important open questions and the high-risk dilemma

2020 ◽  
Vol 22 (12) ◽  
pp. 1723-1724
Author(s):  
Martin Mynarek ◽  
Stefan Rutkowski
Keyword(s):  
High Risk ◽  
Young Children ◽  
Open Questions
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