Plasma cytokines and sleep quality in Parkinson's Disease

2014 ◽  
Author(s):  
Raymond Chong ◽  
Chandramohan Wakade ◽  
Eric Bradley
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Sleep Quality ◽  
Plasma Cytokines

Plasma Cytokines and Sleep Quality in Parkinson's Disease

2014 ◽  
Author(s):  
Raymond Chong ◽  
Chandramohan Wakade ◽  
Eric Bradley
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Sleep Quality ◽  
Plasma Cytokines

scholarly journals Sleep quality assessment in Parkinson's disease patients: Preliminary result

2018 ◽  
Vol 61 ◽  
pp. e257
Author(s):  
W. Haj Hamad ◽  
M. Sghir ◽  
R. Machraoui ◽  
I. Ksibi ◽  
S. Younes ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Sleep Quality ◽  
Quality Assessment

scholarly journals Sleep Quality and Levodopa Intestinal Gel Infusion in Parkinson’s Disease: A Pilot Study

2018 ◽  
Vol 2018 ◽  
pp. 1-6
Author(s):  
Oriol De Fabregues ◽  
Alex Ferré ◽  
Odile Romero ◽  
Manuel Quintana ◽  
José Álvarez-Sabin
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Pilot Study ◽  
Sleep Quality ◽  
Rem Sleep ◽  
Rating Scale ◽  
Sleep Problems ◽  
Periodic Leg Movements ◽  
Before And After ◽  
Hamilton Anxiety Rating Scale

Background. Sleep problems in patients with advanced Parkinson’s disease (PD) have a deleterious impact on quality of life. Objective. To assess the effect of levodopa-carbidopa intestinal gel (LCIG) infusion on sleep quality in advanced PD patients. Methods. Seven patients participated in a prospective pilot study. Before and after 6 months of LCIG infusion, an overnight polysomnography was performed and the Epworth Sleepiness Scale, fatigue scale, Pittsburgh Sleep Quality Index, Beck Depression Inventory, and the Hamilton Anxiety Rating Scale were administered. Results. PSG showed low sleep efficiency. REM sleep without atony was found in 5 patients. After 6 months of LCIG infusion, the percentage of REM sleep decreased as well as the number of arousals especially due to reduction of spontaneous arousals and periodic leg movements during REM sleep, but differences were not statistically significant. Also, scores of all study questionnaires showed a tendency to improve. Conclusion. The results show a trend toward an improvement of sleep quality after 6 months of LCIG infusion, although differences as compared to pretreatment values were not statistically significant. The sleep architecture was not modified by LCIG. Further studies with larger study samples are needed to confirm these preliminary findings.

Analysis of nocturnal hypokinesia and sleep quality in Parkinson’s disease

2018 ◽  
Vol 54 ◽  
pp. 96-101 ◽  
Author(s):  
Fei Xue ◽  
Fu-Yu Wang ◽  
Cheng-Jie Mao ◽  
Si-Ping Guo ◽  
Jing Chen ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Sleep Quality

Widespread Pressure Pain Hyperalgesia Is Not Related to Pain in Patients with Parkinson’s Disease

Pain Medicine ◽  
2019 ◽  
Vol 21 (2) ◽  
pp. 232-238
Author(s):  
María R Ferreira-Sánchez ◽  
Marcos Moreno-Verdú ◽  
Roberto Cano-de-la-Cuerda ◽  
César Fernández-de-las-Peñas ◽  
Javier Güeita-Rodríguez ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Sleep Quality ◽  
Pain Sensitivity ◽  
Pain Processing ◽  
Health Related Quality ◽  
Pressure Pain ◽  
Related Quality ◽  
Health Related

Abstract Objective Pain is one of the most frequent nonmotor impairments in Parkinson’s disease (PD) and is hypothesized to be associated with altered nociceptive pain processing. Our aims were to investigate differences in widespread pressure pain sensitivity between PD patients with and without pain and healthy controls and to assess the relationship of health-related quality of life and sleep quality with pressure pain sensitivity. Methods Nineteen PD patients with pain (12 men, age = 68 ± 9 years), 19 PD patients without pain (11 men, age = 69 ± 8 years), and 19 matched controls participated. Pressure pain thresholds (PPTs) were assessed bilaterally over the cervical spine, the second metacarpal, and the tibialis anterior by an assessor blinded to the subject’s condition. Patients were assessed in a dopamine-medicated (ON) state. Pain intensity (numerical pain rating scale, 0–10), health-related quality of life (39-item Parkinson’s Disease Questionnaire), and sleep quality (Pittsburgh Sleep Quality Index) were also assessed. Results No significant differences existed between PD patients, with or without pain, and healthy controls on PPTs over the cervical spine, the second metacarpal, or the tibialis anterior muscle (all P > 0.3). PPTs were lower in females than in males in all groups (P < 0.01). In PD patients with pain, worse quality of sleep was associated with higher widespread pressure pain sensitivity (–0.607 < r < –0.535, P < 0.05). No other significant association was observed. Conclusions This study revealed no differences in widespread pressure hyperalgesia between PD patients with or without pain (ON state) and controls. Although dopamine may modulate pain responses, other mechanisms seems to also be implicated in altered nociceptive pain processing in patients with PD.

Prolonged-release melatonin in Parkinson's disease patients with a poor sleep quality: A randomized trial

2020 ◽  
Vol 75 ◽  
pp. 50-54 ◽  
Author(s):  
Jong Hyeon Ahn ◽  
Minkyeong Kim ◽  
Suyeon Park ◽  
Wooyoung Jang ◽  
Jinse Park ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Sleep Quality ◽  
Randomized Trial ◽  
Poor Sleep ◽  
Prolonged Release ◽  
Poor Sleep Quality
Sign in / Sign up

Export Citation Format

Share Document