Conversation Equal to Games in Improving Memory Function

2009 ◽  
Keyword(s):  
2010 ◽  
Vol 34 (8) ◽  
pp. S18-S18
Author(s):  
Wei Jiang ◽  
Enyi Wen ◽  
Min Gong ◽  
Yang Bi ◽  
Xiaojuan Zhang ◽  
...  

Author(s):  
Sunmin Park ◽  
Sunna Kang ◽  
Da Sol Kim

Abstract. Folate and vitamin B12(V-B12) deficiencies are associated with metabolic diseases that may impair memory function. We hypothesized that folate and V-B12 may differently alter mild cognitive impairment, glucose metabolism, and inflammation by modulating the gut microbiome in rats with Alzheimer’s disease (AD)-like dementia. The hypothesis was examined in hippocampal amyloid-β infused rats, and its mechanism was explored. Rats that received an amyloid-β(25–35) infusion into the CA1 region of the hippocampus were fed either control(2.5 mg folate plus 25 μg V-B12/kg diet; AD-CON, n = 10), no folate(0 folate plus 25 μg V-B12/kg diet; AD-FA, n = 10), no V-B12(2.5 mg folate plus 0 μg V-B12/kg diet; AD-V-B12, n = 10), or no folate plus no V-B12(0 mg folate plus 0 μg V-B12/kg diet; AD-FAB12, n = 10) in high-fat diets for 8 weeks. AD-FA and AD-VB12 exacerbated bone mineral loss in the lumbar spine and femur whereas AD-FA lowered lean body mass in the hip compared to AD-CON(P < 0.05). Only AD-FAB12 exacerbated memory impairment by 1.3 and 1.4 folds, respectively, as measured by passive avoidance and water maze tests, compared to AD-CON(P < 0.01). Hippocampal insulin signaling and neuroinflammation were attenuated in AD-CON compared to Non-AD-CON. AD-FAB12 impaired the signaling (pAkt→pGSK-3β) and serum TNF-α and IL-1β levels the most among all groups. AD-CON decreased glucose tolerance by increasing insulin resistance compared to Non-AD-CON. AD-VB12 and AD-FAB12 increased insulin resistance by 1.2 and 1.3 folds, respectively, compared to the AD-CON. AD-CON and Non-AD-CON had a separate communities of gut microbiota. The relative counts of Bacteroidia were lower and those of Clostridia were higher in AD-CON than Non-AD-CON. AD-FA, but not V-B12, separated the gut microbiome community compared to AD-CON and AD-VB12(P = 0.009). In conclusion, folate and B-12 deficiencies impaired memory function by impairing hippocampal insulin signaling and gut microbiota in AD rats.


GeroPsych ◽  
2014 ◽  
Vol 27 (4) ◽  
pp. 161-169 ◽  
Author(s):  
Nienke A. Hofrichter ◽  
Sandra Dick ◽  
Thomas G. Riemer ◽  
Carsten Schleussner ◽  
Monique Goerke ◽  
...  

Hippocampal dysfunction and deficits in episodic memory have been reported for both Alzheimer’s disease (AD) and major depressive disorder (MDD). Primacy performance has been associated with hippocampus-dependent episodic memory, while recency may reflect working memory performance. In this study, serial position profiles were examined in a total of 73 patients with MDD, AD, both AD and MDD, and healthy controls (HC) by means of CERAD-NP word list memory. Primacy performance was most impaired in AD with comorbid MDD, followed by AD, MDD, and HC. Recency performance, on the other hand, was comparable across groups. These findings indicate that primacy in AD is impaired in the presence of comorbid MDD, suggesting additive performance decrements in this specific episodic memory function.


2014 ◽  
Author(s):  
Mitchell Metzger ◽  
Morgan Myers ◽  
Emily Embrescia ◽  
David F. Vanata

2013 ◽  
Author(s):  
Gurinder S. Bains ◽  
Lee Berk ◽  
Noha Daher ◽  
Pooja Deshpande ◽  
Everett Lohman ◽  
...  

2019 ◽  
Author(s):  
Steve M. J. Janssen

People tend to recall more specific personal events from adolescence and early adulthood than from other lifetime periods, a finding known as the reminiscence bump. Several explanations have suggested that events from the reminiscence bump are especially emotional, important, or positive, but studies using cue words have not found support for these claims. An alternative account postulates that cognitive abilities function optimally in adolescence and early adulthood, which may cause more memories to be stored in those lifetime periods. Although other studies have previously discussed the cognitive abilities account as a possible explanation for the reminiscence bump, it was only recently shown that cognitive abilities are indeed related to autobiographical memory performance. When this recent finding is combined with previous findings that cognitive abilities as well as autobiographical memory function optimally in adolescence and early adulthood, they suggest that the cognitive abilities account is a promising explanation for the reminiscence bump in the temporal distribution of word-cued memories. However, because the account does not aim to explain the reminiscence bump in the distribution of highly significant events, it should be regarded as complementary to the existing accounts.


Author(s):  
Admink Admink

In the article, the author analyzes the modern model of the phenomenon of a monument of history and culture. The author notes that, as carriers of social information, monuments are considered the most popular phenomena that implement the «memory» function in them. If we pay attention to the equivalents of the word «memory» in other languages, then there is no need for further argumentation for this view. Taking into account that the expression “monument of history and culture” itself has a special paradigm of analysis, there is an initial need to analyze the concept of «memory». The author analyzing the correlation of the concept of «abide» with the concepts of «monument», «monument» reveals the general aspects of this phenomenon. The purpose of the article is to attribute the monument of history and culture to the category of cultural heritage. The initial goal of the science of the study of monuments, which began its formation in the late 80s of the last century in post-Soviet countries, especially in Moscow and Leningrad, was initiated by scientists P. Boyarsky, A. Kulemzin, A. Dyachkov, etc., namely the theoretical the study of the scientific essence of this phenomenon. The author noted that since the second half of the last century, historical and cultural monuments have become the object of research in many sciences, such as philosophy, sociology, history, the study of art and culture, pedagogy, philology, natural science, etc. Key words: abide, historical and cultural monument, cultural heritage, memory. Аналізується сучасна модель феномена пам’ятка історії і культури. Автор зазначає, що як носії соціальної інформації пам’ятки вважаються найбільш популярними явищами, які реалізують у них функцію «пам’яті». Якщо звернути увагу на еквіваленти слова «пам’ять» в інших мовах, то немає необхідності в подальшій аргументації для цього погляду. Беручи до уваги, що саме слово «пам’ятка історії і культури» має особливу парадигму аналізу, існує необхідність аналізу поняття «пам’яті». Автор аналізуючи співвідношення поняття «Абиде» з поняттями «пам’ятник», «монумент» виявляє загальні аспекти цього явище. Мета статті – відносити пам’ятку історії і культури до категорію культурної спадщини. Початкова мета науки про вивчення пам’яток почала своє становлення наприкінці 80-х роках минулого століття в пострадянських країнах, особливо в Москві та Ленінграді з ініціативи вчених П. Боярського, А. Кулезмін, А. Дьячков та ін.. Автор зауважив, що починаючи з другої половини минулого століття пам’ятки історії і культури стали об’єктом досліджень багатьох наук, зокрема таких як філософія, соціологія, історія мистецтва та культури, педагогіка, філологія, природознавство. Ключові слова: Абиде, пам’ятка історії та культури, культурна спадщина, пам’ять.


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