Confidence Interval Pictures Can Give Better Inference Than Significance Testing

2006 ◽  
Author(s):  
Geoff Cumming ◽  
Melissa Coulson ◽  
Michelle Healey ◽  
Fiona Fidler
Keyword(s):  
Confidence Interval ◽  
Significance Testing

Confidence Intervals

2009 ◽  
Vol 217 (1) ◽  
pp. 15-26 ◽  
Author(s):  
Geoff Cumming ◽  
Fiona Fidler
Keyword(s):  
Confidence Interval ◽  
Confidence Intervals ◽  
Null Hypothesis ◽  
Prediction Intervals ◽  
Effect Sizes ◽  
Significance Testing ◽  
Null Hypothesis Significance Testing ◽  
P Values ◽  
Standardized Effect Sizes ◽  
Mainstream Science

Most questions across science call for quantitative answers, ideally, a single best estimate plus information about the precision of that estimate. A confidence interval (CI) expresses both efficiently. Early experimental psychologists sought quantitative answers, but for the last half century psychology has been dominated by the nonquantitative, dichotomous thinking of null hypothesis significance testing (NHST). The authors argue that psychology should rejoin mainstream science by asking better questions – those that demand quantitative answers – and using CIs to answer them. They explain CIs and a range of ways to think about them and use them to interpret data, especially by considering CIs as prediction intervals, which provide information about replication. They explain how to calculate CIs on means, proportions, correlations, and standardized effect sizes, and illustrate symmetric and asymmetric CIs. They also argue that information provided by CIs is more useful than that provided by p values, or by values of Killeen’s prep, the probability of replication.

Reconnecting data analysis and research design: Who needs a confidence interval?

1998 ◽  
Vol 21 (2) ◽  
pp. 203-204 ◽  
Author(s):  
Andrew F. Hayes
Keyword(s):  
Data Analysis ◽  
Confidence Interval ◽  
Confidence Intervals ◽  
Research Design ◽  
Research Evaluation ◽  
Evaluation Process ◽  
Significance Testing ◽  
Significance Tests ◽  
Research Findings

Chow illustrates the important role played by significance testing in the evaluation of research findings. Statistics and the goals of research should be treated as both interrelated and separate parts of the research evaluation process – a message that will benefit all who read Chow's book. The arguments are especially pertinent to the debate over the relative merits of confidence intervals and significance tests.

Development of apical pits in chloride cells of the gills of Pimephales promelas after chronic exposure to acid water

1983 ◽  
Vol 41 ◽  
pp. 462-463
Author(s):  
Richard L. Leino ◽  
Jon G. Anderson ◽  
J. Howard McCormick
Keyword(s):  
Confidence Interval ◽  
Chronic Exposure ◽  
Lake Superior ◽  
Pimephales Promelas ◽  
Chloride Cells ◽  
Fathead Minnows ◽  
Secondary Lamellae ◽  
Untreated Water ◽  
Water Ph ◽  
Flow Through

Groups of 12 fathead minnows were exposed for 129 days to Lake Superior water acidified (pH 5.0, 5.5, 6.0 or 6.5) with reagent grade H2SO4 by means of a multichannel toxicant system for flow-through bioassays. Untreated water (pH 7.5) had the following properties: hardness 45.3 ± 0.3 (95% confidence interval) mg/1 as CaCO3; alkalinity 42.6 ± 0.2 mg/1; Cl- 0.03 meq/1; Na+ 0.05 meq/1; K+ 0.01 meq/1; Ca2+ 0.68 meq/1; Mg2+ 0.26 meq/1; dissolved O2 5.8 ± 0.3 mg/1; free CO2 3.2 ± 0.4 mg/1; T= 24.3 ± 0.1°C. The 1st, 2nd and 3rd gills were subsequently processed for LM (methacrylate), TEM and SEM respectively.Three changes involving chloride cells were correlated with increasing acidity: 1) the appearance of apical pits (figs. 2,5 as compared to figs. 1, 3,4) in chloride cells (about 22% of the chloride cells had pits at pH 5.0); 2) increases in their numbers and 3) increases in the % of these cells in the epithelium of the secondary lamellae.

Efficacy of Vitamin D on Chronic Heart Failure Among Adults

2020 ◽  
Vol 90 (1-2) ◽  
pp. 49-58 ◽  
Author(s):  
Wang Chunbin ◽  
Wang Han ◽  
Cai Lin
Keyword(s):  
Heart Failure ◽  
Vitamin D ◽  
Chronic Heart Failure ◽  
Left Ventricular Ejection Fraction ◽  
Confidence Interval ◽  
Left Ventricular ◽  
Left Ventricular Ejection ◽  
Controlled Trials ◽  
Ventricular Ejection Fraction ◽  
Randomized Controlled

Abstract. Vitamin D deficiency commonly occurs in chronic heart failure. Whether additional vitamin D supplementation can be beneficial to adults with chronic heart failure remains unclear. We conducted a meta-analysis to derive a more precise estimation. PubMed, Embase, and Cochrane databases were searched on September 8, 2016. Seven randomized controlled trials that investigated the effects of vitamin D on cardiovascular outcomes in adults with chronic heart failure, and comprised 592 patients, were included in the analysis. Compared to placebo, vitamin D, at doses ranging from 2,000 IU/day to 50,000 IU/week, could not improve left ventricular ejection fraction (Weighted mean difference, WMD = 3.31, 95% confidence interval, CL = −0.93 to 7.55, P < 0.001, I2 = 92.1%); it also exerts no beneficial effects on the 6 minute walk distance (WMD = 18.84, 95% CL = −24.85 to 62.52, P = 0.276, I2 = 22.4%) and natriuretic peptide (Standardized mean difference, SMD = −0.39, 95% confidence interval CL = −0.48 to 0.69, P < 0.001, I2 = 92.4%). However, a dose-response analysis from two studies demonstrated an improved left ventricular ejection fraction with vitamin D at a dose of 4,000 IU/day (WMD = 6.58, 95% confidence interval CL = −4.04 to 9.13, P = 0.134, I2 = 55.4%). The results showed that high dose vitamin D treatment could potentially benefit adults with chronic heart failure, but more randomized controlled trials are required to confirm this result.

Sign in / Sign up

Export Citation Format

Share Document