Spatial vision: From the stimulus through the single nerve membrane to perception

Author(s):  
Leonard Matin ◽  
Wenxun Li
2020 ◽  
Vol 16 ◽  
pp. 174480692092785 ◽  
Author(s):  
Mayumi Sonekatsu ◽  
Hiroshi Yamada ◽  
Jianguo G Gu

An electrophysiological technique that can record nerve impulses from a single nerve fiber is indispensable for studying modality-specific sensory receptors such as low threshold mechanoreceptors, thermal receptors, and nociceptors. The teased-fiber single-unit recording technique has long been used to resolve impulses that are likely to be from a single nerve fiber. The teased-fiber single-unit recording technique involves tedious nerve separation procedures, causes nerve fiber impairment, and is not a true single-fiber recording method. In the present study, we describe a new and true single-fiber recording technique, the pressure-clamped single-fiber recording method. We have applied this recording technique to mouse whisker hair follicle preparations with attached whisker afferents as well as to skin-nerve preparations made from mouse hindpaw skin and saphenous nerves. This new approach can record impulses from rapidly adapting mechanoreceptors (RA), slowly adapting type 1 mechanoreceptors (SA1), and slowly adapting type 2 mechanoreceptors (SA2) in these tissue preparations. We have also applied the pressure-clamped single-fiber recordings to record impulses on Aβ-fibers, Aδ-fibers, and C-fibers. The pressure-clamped single-fiber recording technique provides a new tool for sensory physiology and pain research.


1972 ◽  
Vol 34 (2) ◽  
pp. 151-172 ◽  
Author(s):  
Richard A. Arndt ◽  
James D. Bond ◽  
L. David Roper

2014 ◽  
Vol 14 (9) ◽  
pp. 18-18 ◽  
Author(s):  
A. H. Weiss ◽  
T. Biron ◽  
I. Lieder ◽  
R. Y. Granot ◽  
M. Ahissar
Keyword(s):  

2004 ◽  
Vol 45 (3) ◽  
pp. 932 ◽  
Author(s):  
Trevor J. McGill ◽  
Robert M. Douglas ◽  
Raymond D. Lund ◽  
Glen T. Prusky
Keyword(s):  

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