Community prevention efforts to reduce the spread of AIDS associated with intravenous drug abuse.

1990 ◽  
Author(s):  
Robert J. Battjes ◽  
Carl G. Leukefeld ◽  
Zili Amsel
Keyword(s):  
Drug Abuse ◽  
Intravenous Drug ◽  
Intravenous Drug Abuse ◽  
Community Prevention

scholarly journals Surgical treatment of infective endocarditis in intravenous drug abusers

2021 ◽  
Vol 16 (1) ◽  
Author(s):  
Alina Zubarevich ◽  
Marcin Szczechowicz ◽  
Anja Osswald ◽  
Jerry Easo ◽  
Arian Arjomandi Rad ◽  
...  
Keyword(s):  
Surgical Treatment ◽  
Drug Abuse ◽  
Infective Endocarditis ◽  
Mortality Rates ◽  
Blood Cultures ◽  
Intravenous Drug ◽  
Intravenous Drug Abuse ◽  
Enterococcus Species ◽  
Function Impairment

Abstract Background Despite current progress in antibiotic therapy and medical management, infective endocarditis remains a serious condition presenting with high mortality rates. It also is a life-threatening complication in patients with a history of chronic intravenous drug abuse. In this study, we analyzed our institutional experience on the surgical therapy of infective endocarditis in patients with active intravenous drug abuse. The aim of the study is to identify the predictive factors of mortality and morbidity in this subgroup of patients. Methods Between 2007 and 2020, a total of 24 patients (7 female, mean age 38.5 ± 8.7) presenting with active intravenous drug abuse underwent a surgical treatment for the infective endocarditis at out center. The primary endpoint was survival at 30th day after the surgery. The secondary composite endpoint included freedom from death, recurrent endocarditis, re-do surgery, and postoperative stroke during the follow-up period. Mean follow-up was 4.2 ± 4.3 years. Results Staphylococcus species was the most common pathogen detected in the preoperative blood cultures. Infection caused by Enterococcus species as well as liver function impairment were identified as mortality predictor factors. Logistic EuroSCORE and EusoSCORE-II were also predictive factors for mortality in univariate analysis. Survival at 1 and 3 years was 78 and 72% respectively. Thirty-day survival was 88%. 30-day freedom from combined endpoint was 83% and after 1 and 3 years, 69 and 58% of the patients respectively were free from combined endpoint. Five patients (20.8%) were readmitted with recurrent infective endocarditis. Conclusion In patients presenting with active intravenous drug abuse, treatment of infective endocarditis should be performed as aggressively as possible and should be followed by antibiotic therapy to avoid high mortality rates and recurrent endocarditis. Early intervention is advisable in patients with an infective endocarditis and enterococcus species in the preoperative blood cultures, liver function deterioration as well as cardiac function impairment. Attention should be also payed to addiction treatment, due to the elevated relapse rate in patients who actively inject drugs. However, larger prospective studies are necessary to support our results. As septic shock is the most frequent cause of death, new treatment options, e.g. blood purification should be evaluated.

Intravenous drug abuse and Type 1 diabetes: financial and healthcare implications

2004 ◽  
Vol 21 (12) ◽  
pp. 1269-1273 ◽  
Author(s):  
S. A. Saunders ◽  
J. Democratis ◽  
J. Martin ◽  
I. A. Macfarlane
Keyword(s):  
Type 1 Diabetes ◽  
Drug Abuse ◽  
Intravenous Drug ◽  
Intravenous Drug Abuse

Widespread pulmonary granulomatosis following long time intravenous drug abuse—A case report

2010 ◽  
Vol 197 (1-3) ◽  
pp. e27-e30 ◽  
Author(s):  
R.B. Dettmeyer ◽  
M.A. Verhoff ◽  
B. Brückel ◽  
D. Walter
Keyword(s):  
Case Report ◽  
Drug Abuse ◽  
Intravenous Drug ◽  
Intravenous Drug Abuse ◽  
Long Time

Intravenous drug abuse is an indication for antepartum screening for RH alloimmunization

1999 ◽  
Vol 263 (1-2) ◽  
pp. 73-75 ◽  
Author(s):  
J. A. S. Dimer ◽  
Matthias David ◽  
Joachim W. Dudenhausen
Keyword(s):  
Drug Abuse ◽  
Intravenous Drug ◽  
Intravenous Drug Abuse
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