Biological and medical aspects of ionizing radiation; spinal reflex activity and local X-irradiation.

1956 ◽  
Author(s):  
Eugene B. Konecci ◽  
M. B. Danford
Keyword(s):  
Ionizing Radiation ◽  
Spinal Reflex ◽  
Reflex Activity ◽  
X Irradiation

No evidence for contribution of nitric oxide to spinal reflex activity in the rat spinal cord in vitro

1995 ◽  
Vol 188 (2) ◽  
pp. 121-124 ◽  
Author(s):  
S.W.N. Thompson ◽  
R. Babbedge ◽  
T. Levers ◽  
A. Dray ◽  
L. Urban
Keyword(s):  
Nitric Oxide ◽  
Spinal Cord ◽  
Spinal Reflex ◽  
Reflex Activity ◽  
Rat Spinal Cord

Effects of thiosemicarbazide on spinal reflex activity

Neurology ◽  
1960 ◽  
Vol 10 (3) ◽  
pp. 267-267 ◽  
Author(s):  
E. Eidelberg ◽  
N. A. Buchwald
Keyword(s):  
Spinal Reflex ◽  
Reflex Activity

Orexin-A modulates glutamatergic NMDA-dependent spinal reflex potentiation via inhibition of NR2B subunit

2008 ◽  
Vol 295 (1) ◽  
pp. E117-E129 ◽  
Author(s):  
Hsien-Yu Peng ◽  
Hung-Ming Chang ◽  
Sarah Y. Chang ◽  
Kwong-Chung Tung ◽  
Shin-Da Lee ◽  
...  
Keyword(s):  
Afferent Input ◽  
Spinal Reflex ◽  
Reflex Activity ◽  
Nr2b Subunit ◽  
Orexin A ◽  
Hypothalamic Area ◽  
Available N ◽  
Test Stimulation ◽  
Neural Transmission ◽  
Novel Target

Glucose-sensitive neurons in the lateral hypothalamic area produce orexin-A (OxA) as well as orexin-B (OxB) and send their axons to the spinal dorsal horn, which predominantly expresses orexin receptor-1 (OX-1), showing a higher sensitivity to OxA. The purpose of the present study was to assess the effects of OxA on the induction of a novel form of activity-dependent reflex potentiation, spinal reflex potentiation (SRP), in the pelvic-urethral reflex activity. External urethra sphincter electromyogram in response to pelvic afferent nerve test stimulation (TS; 1/30 Hz) or repetitive stimulation (RS; 1 Hz) was recorded in anesthetized rats. TS evoked a baseline reflex activity, whereas RS produced SRP, which was abolished by intrathecal OxA (30 nM, 10 μl). Intrathecal SB-408124 (10 μM, 10 μl), an OX-1 antagonist, reversed the abolition on SRP caused by OxA. Although there is, so far, no NR2A- and NR2B-specific agonist available, N-methyl-d-aspartate (NMDA) reversed the abolition on the RS-induced SRP caused by the co-administration of OxA and Co-101244 (30 nM, 10 μl; an NMDA NR2B subunit antagonist), but it did not reverse the abolition by the co-administration of OxA and PPPA (300 nM, 10 μl; an NMDA NR2A subunit antagonist). In conclusion, the activation of descending orexinergic fibers may inhibit the repetitive afferent input-induced central sensitization of pelvic-urethral reflex activity and urethra hyperactivity, indicating that spinal orexinergic neural transmission may be a novel target for the treatment of patients with neuropathetic or postinflammatory pain of pelvic origin.

Spinal Reflex Activity

2011 ◽  
Vol 26 (2) ◽  
pp. 188-196 ◽  
Author(s):  
Michèle Hubli ◽  
Volker Dietz ◽  
Marc Bolliger
Keyword(s):  
Spinal Reflex ◽  
Reflex Activity

scholarly journals Effects of catecholamines on spinal reflex activity

1976 ◽  
Vol 26 ◽  
pp. 98
Author(s):  
Teruhiko Matsumiya ◽  
Yasuo Watanabe ◽  
Tetsuo Oka
Keyword(s):  
Spinal Reflex ◽  
Reflex Activity
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