Monitoring birth defect rates in a cohort of perinatally HIV-exposed infants

2005 ◽  
Author(s):  
Glenn Copeland ◽  
Nilsa Mack ◽  
Yolande Moore ◽  
Eve Mokotoff
Keyword(s):  
Birth Defect ◽  
Hiv Exposed Infants ◽  
Hiv Exposed

scholarly journals Efficacy of Mobile phone use on adherence to Nevirapine prophylaxis and retention in care among the HIV-exposed infants in prevention of mother to child transmission of HIV: a randomized controlled trial

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Lilian M. N. Kebaya ◽  
Dalton Wamalwa ◽  
Nyambura Kariuki ◽  
Bashir Admani ◽  
Philip Ayieko ◽  
...  
Keyword(s):  
Mobile Phone ◽  
Infant Feeding ◽  
Retention In Care ◽  
Control Group ◽  
Hiv Exposed Infants ◽  
Randomized Controlled ◽  
Phone Calls ◽  
Hiv Exposed ◽  
To Receive

Abstract Background HIV is a major contributor to infant mortality. A significant gap remains between the uptake of infant and maternal antiretroviral regimens and only a minority of HIV-exposed infants receives prophylaxis and safe infant feeding. Losses to follow-up of HIV-exposed infants are associated with shortcomings of facility-based PMTCT models with weak community support of linkages. Use of mobile phones offers an opportunity for improving care and promoting retention assessed by timely attendance of scheduled appointments for the mother-baby pairs and achievement of an HIV-free generation. The objective of this study was to compare self-reported adherence to infant Nevirapine (NVP) prophylaxis and retention in care assessed by timely attendance of scheduled appointments over 10 weeks in HIV exposed infants randomized to 2-weekly mobile phone calls (intervention) versus no phone calls (control). Methods In this open label randomized controlled study, one hundred and fifty HIV infected women drawn from 3 health facilities in Western Kenya and their infants were randomly assigned to receive either phone-based reminders on PMTCT messages or standard health care messages (no calls) within 24 h of delivery. Women in the intervention arm continued to receive fortnightly phone calls. At 6- and 10-weeks following randomization we collected data on infant adherence to Nevirapine, mode of infant feeding, early HIV testing and retention in care in both study arms. All analyses were intention to treat. Results At 6 weeks follow-up, 90.7% (n = 68) of participants receiving phone calls reported adherence to infant NVP prophylaxis, compared with 72% (n = 54) of participants in the control group (p = 0.005). Participants in the intervention arm were also significantly more likely to remain in care than participants in the control group [78.7% (n = 59) vs. 58.7% (n = 44), p = 0.009 at 6 weeks and 69.3% (n = 52) vs. 37.3% (n = 28), p < 0.001 at 10 weeks]. Conclusions These results suggest that phone calls are potentially an important tool to improve adherence to infant NVP prophylaxis and retention in care for HIV-exposed infants. Trial registration PACTR202007654729602. Registered 6 June 2018 - Retrospectively registered, https://pactr.samrc.ac.za/TrialDisplay.aspx?TrialID=3449

scholarly journals Toll-Like Receptor (TLR) 9 polymorphism is associated with increased Epstein-Barr virus and Cytomegalovirus acquisition in HIV-exposed infants

AIDS ◽  
2017 ◽  
pp. 1 ◽  
Author(s):  
Kristin Beima-Sofie ◽  
Dalton Wamalwa ◽  
Elizabeth Maleche-Obimbo ◽  
Jairam R. Lingappa ◽  
Romel Mackelprang ◽  
...  
Keyword(s):  
Epstein Barr Virus ◽  
Toll Like Receptor ◽  
Hiv Exposed Infants ◽  
Barr Virus ◽  
Epstein Barr ◽  
Hiv Exposed

Delayed seroreversion of specifical antibody against HIV in HIV‐exposed infants: A retrospective cohort study

HIV Medicine ◽  
2020 ◽  
Vol 21 (11) ◽  
pp. 718-721
Author(s):  
A Liu ◽  
L Zhang ◽  
X Zhang ◽  
HW Zhang ◽  
YM Tian ◽  
...  
Keyword(s):  
Cohort Study ◽  
Retrospective Cohort Study ◽  
Retrospective Cohort ◽  
Hiv Exposed Infants ◽  
Hiv Exposed

scholarly journals The Pharmacogenetics of NAT2 Enzyme Maturation in Perinatally HIV Exposed Infants Receiving Isoniazid

2012 ◽  
Vol 52 (4) ◽  
pp. 511-519 ◽  
Author(s):  
Rui Zhu ◽  
Jennifer J. Kiser ◽  
Heiner I. Seifart ◽  
Cedric J. Werely ◽  
Charles D. Mitchell ◽  
...  
Keyword(s):  
Hiv Exposed Infants ◽  
Enzyme Maturation ◽  
Hiv Exposed

scholarly journals Difficulties with interpreting cytokines/chemokines values in disease states

2016 ◽  
Vol 22 (1) ◽  
pp. 2
Author(s):  
Prakash Jeena
Keyword(s):  
Hiv Exposed Infants ◽  
Interesting Article ◽  
Disease States ◽  
Hiv Exposed

This edition of the journal features an interesting article on cytokine/chemokine profiles in HIV exposed infants with hypoxic pneumonia.

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