UCS Intensity-Dependent Attenuation of Infantile Amnesia in Pre-Weanling Rats

1999 ◽  
Author(s):  
Robert W. Flint ◽  
Michael D. Bunsey ◽  
David C. Riccio
Keyword(s):  
Weanling Rats ◽  
Infantile Amnesia

scholarly journals Plasma and Urinary Amino Acid-Derived Catabolites as Potential Biomarkers of Protein and Amino Acid Deficiency in Rats

Nutrients ◽  
2021 ◽  
Vol 13 (5) ◽  
pp. 1567
Author(s):  
Joanna Moro ◽  
Nadezda Khodorova ◽  
Daniel Tomé ◽  
Claire Gaudichon ◽  
Catherine Tardivel ◽  
...  
Keyword(s):  
Amino Acid ◽  
Dietary Intakes ◽  
Analysis Model ◽  
Factorial Method ◽  
New Methods ◽  
Food And Agriculture ◽  
Food And Agriculture Organization ◽  
Weanling Rats ◽  
Urinary Amino ◽  
One Way Anova

Objective: Dietary intakes must cover protein and essential amino acid (EAA) requirements. For this purpose, different methods have been developed such as the nitrogen balance method, factorial method, or AA tracer studies. However, these methods are either invasive or imprecise, and the Food and Agriculture Organization of the United Nations (FAO, 2013) recommends new methods and, in particular, metabolomics. The aim of this study is to determine total protein/EAA requirement in the plasma and urine of growing rats. Methods: 36 weanling rats were fed with diets containing 3, 5, 8, 12, 15, and 20% protein for 3 weeks. During experimentation, urine was collected using metabolic cages, and blood from the portal vein and vena was taken at the end of the experiment. Metabolomics analyses were performed using LC-MS, and the data were analyzed with a multivariate analysis model, partial least Squares (PLS) regression, and independent component-discriminant analysis (ICDA). Each discriminant metabolite identified by PLS or ICDA was tested by one-way ANOVA to evaluate the effect of diet. Results: PLS and ICDA allowed us to identify discriminating metabolites between different diet groups. Protein deficiency led to an increase in the AA catabolism enzyme systems inducing the production of breakdown metabolites in the plasma and urine. Conclusion: These results indicate that metabolites are specific for the state of EAA deficiency and sufficiency. Some types of biomarkers such as AA degradation metabolites appear to be specific candidates for protein/EAA requirement.

Brain resistance to protein loss on restricted protein intake in weanling rats

1979 ◽  
Vol 4 (6) ◽  
pp. 747-756 ◽  
Author(s):  
Richard Ross Rebert ◽  
Robert B. Chronister ◽  
Herbert E. Longenecker ◽  
L.Preston Mercer
Keyword(s):  
Protein Intake ◽  
Protein Loss ◽  
Weanling Rats

THE ROLE OF THE MOTHER IN 131I METABOLISM OF SUCKING AND WEANLING RATS

1965 ◽  
Vol 43 (3) ◽  
pp. 431-436 ◽  
Author(s):  
M. Samel ◽  
A. Caputa
Keyword(s):  
Urinary Bladder ◽  
In Utero ◽  
The State ◽  
Newborn Rats ◽  
Weanling Rats ◽  
Immature Rats ◽  
Other Substances ◽  
Old Rats

In newborn rats the mother provokes the emptying of the urinary bladder by stimulating the perineum with her tongue. The possibility that mothers may thereby ingest the urine of their young has been studied by means of 131I on nine litters of rats aged 10 to 29 days. The results indicate that a considerable quantity of 131I administered intraperitoneally to 10- and 18-day-old rats, which were then reunited with their mothers for 4 hours, reappears in the organism of uninjected nurslings after passing through the organism of the mother. The amount of 131I transferred from injected rats into the bodies of isolated uninjected rats of the same litter decreased during the period of weaning. The observed recirculation of 131I between immature rats and their mothers in both directions may represent a saving mechanism which might include several other substances and would compensate for their loss via the milk, and suggests a new aspect of maternal–neonatal interrelationship which appears as a continuation of the state existing in utero.

Protein quality assessment by the use of weanling rats. 1.—Some factors affecting growth measurements

1968 ◽  
Vol 19 (6) ◽  
pp. 308-315
Author(s):  
D. L. Frape ◽  
R. W. Hocken ◽  
J. Wilkinson ◽  
J. C. Dickins ◽  
L. G. Chubb
Keyword(s):  
Quality Assessment ◽  
Protein Quality ◽  
Factors Affecting ◽  
Weanling Rats

Hypothalamic obesity: Comparison of radio-frequency and electrolytic lesions in weanling rats

1989 ◽  
Vol 45 (1) ◽  
pp. 127-132 ◽  
Author(s):  
Bruce M. King ◽  
Penny M. Daigrepont ◽  
Robert E. Michel ◽  
Cari A. Zansler ◽  
Jamal I. Ahmed ◽  
...  
Keyword(s):  
Radio Frequency ◽  
Hypothalamic Obesity ◽  
Weanling Rats ◽  
Electrolytic Lesions

Toxicity of selenium to post-weanling rats

1966 ◽  
Vol 9 (3) ◽  
pp. 477-484 ◽  
Author(s):  
A.W. Halverson ◽  
I.S. Palmer ◽  
P.L. Guss
Keyword(s):  
Weanling Rats

scholarly journals The effect of amino-acid-supplemented wheat gluten on cholesterol metabolism in the rat

1985 ◽  
Vol 53 (1) ◽  
pp. 25-30 ◽  
Author(s):  
M. Bassat ◽  
S. Mokady
Keyword(s):  
Amino Acid ◽  
Cholesterol Metabolism ◽  
Cholesterol Biosynthesis ◽  
Wheat Gluten ◽  
Blood Cholesterol ◽  
Amino Acid Supplementation ◽  
Faecal Excretion ◽  
Weanling Rats ◽  
Low Levels

1. The effect of lysine- and threonine-supplemented wheat gluten on cholesterol metabolism was studied using male weanling rats. Animals were fed on cholesterol-free diets containing 100 or 200 g gluten/kg with or without amino acid supplementation, and compared with animals given 50, 100 and 200 g casein/kg diets, for 3 weeks.2. A hypocholesterolaemic effect observed with the wheat gluten-fed rats, compared with the animals given 100 and 200 g casein/kg diets, was accompanied by increased turnover of cholesterol as expressed by enhanced cholesterol biosynthesis and increased faecal excretion of cholesterol and bile acids. This effect was not abolished by lysine and threonine supplementation.3. Low levels of blood cholesterol were also observed in the rats fed on the 50 g casein/kg diet. However, a different mechanism, related to impairment of cholesterol transport from the liver, was most likely responsible for the hypocholesterolaemia found in these protein-malnourished animals.4. The effect on cholesterol metabolism produced by dietary wheat gluten was independent of the low quality of the protein and of its specific deficiency in lysine and threonine.

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