Alcohol Abuse in Clients With Mental Retardation

2000 ◽  
Author(s):  
N. B. McGillicuddy ◽  
H. T. Blane
2010 ◽  
Vol 2010 ◽  
pp. 1-5
Author(s):  
Michele Fornaro ◽  
Giovanni Ciampa ◽  
Nicola Mosti ◽  
Alessandra Del Carlo ◽  
Giuseppe Ceraudo ◽  
...  

Mental Retardation (MR) is a developmental disability characterized by impairments in adaptive daily life skills and difficulties in social and interpersonal functioning. Since multiple causes may contribute to MR, associated clinical pictures may vary accordingly. Nevertheless, when psychiatric disorders as Treatment Resistant Depression (TRD) and/or alcohol abuse co-exist, their proper detection and management is often troublesome, essentially due to a limited vocabulary MR people could use to describe their symptoms, feelings and concerns, and the lack of reliable screening tools. Furthermore, MR people are among the most medicated subjects, with (over) prescription of antidepressants and/or typical antipsychotics being the rule rather than exception. Thus, treatment resistance or even worsening of depression, constitute frequent occurrences. This report describes the case of a person with MR who failed to respond to repetitive trials of antidepressant monotherapies, finally recovering using aripiprazole to fluvoxamine augmentation upon consideration of a putative bipolar diathesis for “agitated” TRD. Although further controlled investigations are needed to assess a putative bipolar diathesis in some cases of MR associated to TRD, prudence is advised in the long-term prescription of antidepressant monotherapies in such conditions.


Author(s):  
Line Buhl ◽  
David Muirhead

There are four lysosomal diseases of which the neuronal ceroid lipofuscinosis is the rarest. The clinical presentation and their characteric abnormal ultrastructure subdivide them into four types. These are known as the Infantile form (Santavuori-Haltia), Late infantile form (Jansky-Bielschowsky), Juvenile form (Batten-Spielmeyer-Voght) and the Adult form (Kuph's).An 8 year old Omani girl presented wth myclonic jerks since the age of 4 years, with progressive encephalopathy, mental retardation, ataxia and loss of vision. An ophthalmoscopy was performed followed by rectal suction biopsies (fig. 1). A previous sibling had died of an undiagnosed neurological disorder with a similar clinical picture.


Addiction ◽  
1997 ◽  
Vol 92 (12) ◽  
pp. 1705-1716 ◽  
Author(s):  
Sandra K. Burge ◽  
Nancy Amodei ◽  
Bernice Elkin ◽  
Selina Catala ◽  
Sylvia Rodriguez Andrew ◽  
...  

2005 ◽  
Vol 38 (12) ◽  
pp. 16-17
Author(s):  
ALICIA AULT
Keyword(s):  

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