Supplemental Material for Genetic Influences on the Interactionist Model of Socioeconomic Development: Incorporating Polygenic Scores for Educational Attainment Into Developmental Research Using the Family Transitions Project (FTP)

2021 ◽  
Keyword(s):  
Educational Attainment ◽  
Socioeconomic Development ◽  
Genetic Influences ◽  
Developmental Research ◽  
Family Transitions ◽  
Polygenic Scores ◽  
The Family

scholarly journals Comparison of Adopted and Nonadopted Individuals Reveals Gene–Environment Interplay for Education in the UK Biobank

2020 ◽  
Vol 31 (5) ◽  
pp. 582-591 ◽  
Author(s):  
Rosa Cheesman ◽  
Avina Hunjan ◽  
Jonathan R. I. Coleman ◽  
Yasmin Ahmadzadeh ◽  
Robert Plomin ◽  
...  
Keyword(s):  
Educational Attainment ◽  
Home Environment ◽  
Family Environment ◽  
Adoptive Parents ◽  
Genetic Influences ◽  
Uk Biobank ◽  
Gene Environment ◽  
Polygenic Scores ◽  
The Family ◽  
The Uk

Polygenic scores now explain approximately 10% of the variation in educational attainment. However, they capture not only genetic propensity but also information about the family environment. This is because of passive gene–environment correlation, whereby the correlation between offspring and parent genotypes results in an association between offspring genotypes and the rearing environment. We measured passive gene–environment correlation using information on 6,311 adoptees in the UK Biobank. Adoptees’ genotypes were less correlated with their rearing environments because they did not share genes with their adoptive parents. We found that polygenic scores were twice as predictive of years of education in nonadopted individuals compared with adoptees ( R2s = .074 vs. .037, p = 8.23 × 10−24). Individuals in the lowest decile of polygenic scores for education attained significantly more education if they were adopted, possibly because of educationally supportive adoptive environments. Overall, these results suggest that genetic influences on education are mediated via the home environment.

scholarly journals Polygenic Scores for Smoking and Educational Attainment have Independent Influences on Academic Success and Adjustment in Adolescence and Educational Attainment in Adulthood

2021 ◽  
Author(s):  
Brian M. Hicks ◽  
D. Angus Clark ◽  
Joseph D. Deak ◽  
Jonathan Schaefer ◽  
Mengzhen Liu ◽  
...  
Keyword(s):  
Academic Success ◽  
Educational Attainment ◽  
Academic Motivation ◽  
Academic Adjustment ◽  
Genetic Influences ◽  
Behavioral Disinhibition ◽  
Discipline Problems ◽  
Academic Variables ◽  
Polygenic Scores

Educational success is associated with greater quality of life and depends, in part, on heritable cognitive and non-cognitive traits. We used polygenic scores (PGS) for smoking—a measure of genetic influences on behavioral disinhibition—and educational attainment to examine different genetic influences on facets of academic adjustment in adolescence and educational attainment in adulthood. PGSs were calculated for participants of the Minnesota Twin Family Study (N = 3225) and included as predictors of grades, academic motivation, and discipline problems at ages 11, 14, and 17 years-old and educational attainment at age 29. Smoking and educational attainment PGSs had significant incremental associations with each academic variable. About half of the adjusted effects of the smoking and educational PGSs on educational attainment at age 29 were mediated by the academic variables in adolescence. Distinct genetic influences related to behavioral disinhibition and educational attainment contribute to academic adjustment in adolescence and educational attainment in adulthood.

Major Discrimination Experiences, Education, and Genes

2019 ◽  
Vol 32 (7-8) ◽  
pp. 753-763
Author(s):  
Aniruddha Das
Keyword(s):  
Educational Attainment ◽  
Life Course ◽  
Mediation Analysis ◽  
Healthy Aging ◽  
Genetic Influences ◽  
Health And Retirement Study ◽  
Direct Effects ◽  
Polygenic Scores ◽  
Retirement Study

Objectives: Rather than acting as a buffer, educational attainment has a known positive linkage with major experiences of lifetime discrimination. Recently established genetic roots of education, then, may also influence such reports. The current study examined these patterns. Methods: Data were from the 2010 wave of the Health and Retirement Study. Polygenic scores indexed one’s genetic propensity for more education. Mediation analysis was through counterfactual methods. Results: Among Whites as well as Blacks, genetic antecedents of education also elevated discrimination reports. Part of this influence was channeled through education. At least among Whites, direct effects were also found. Discussion: Major discrimination experiences seem partly rooted in genes. Mechanisms are tentatively suggested. Direct genetic influences, in particular, indicate potential confounding of previously estimated linkages between discrimination and health or life course factors. Given the range of these prior results, and their implications for healthy aging, investigation of these possibilities is needed.

scholarly journals Polygenic scores for smoking and educational attainment have independent influences on academic success and adjustment in adolescence and educational attainment in adulthood

PLoS ONE ◽  
2021 ◽  
Vol 16 (8) ◽  
pp. e0255348
Author(s):  
Brian M. Hicks ◽  
D. Angus Clark ◽  
Joseph D. Deak ◽  
Jonathan D. Schaefer ◽  
Mengzhen Liu ◽  
...  
Keyword(s):  
Academic Success ◽  
Educational Attainment ◽  
Academic Motivation ◽  
Academic Adjustment ◽  
Genetic Influences ◽  
Educational Success ◽  
Discipline Problems ◽  
Academic Variables ◽  
Polygenic Scores

Educational success is associated with greater quality of life and depends, in part, on heritable cognitive and non-cognitive traits. We used polygenic scores (PGS) for smoking and educational attainment to examine different genetic influences on facets of academic adjustment in adolescence and educational attainment in adulthood. PGSs were calculated for participants of the Minnesota Twin Family Study (N = 3225) and included as predictors of grades, academic motivation, and discipline problems at ages 11, 14, and 17 years-old, cigarettes per day from ages 14 to 24 years old, and educational attainment in adulthood (mean age 29.4 years). Smoking and educational attainment PGSs had significant incremental associations with each academic variable and cigarettes per day. About half of the adjusted effects of the smoking and education PGSs on educational attainment in adulthood were mediated by the academic variables in adolescence. Cigarettes per day from ages 14 to 24 years old did not account for the effect of the smoking PGS on educational attainment, suggesting the smoking PGS indexes genetic influences related to general behavioral disinhibition. In sum, distinct genetic influences measured by the smoking and educational attainment PGSs contribute to academic adjustment in adolescence and educational attainment in adulthood.

scholarly journals Educational Attainment and Personality Are Genetically Intertwined

2017 ◽  
Vol 28 (11) ◽  
pp. 1631-1639 ◽  
Author(s):  
René Mõttus ◽  
Anu Realo ◽  
Uku Vainik ◽  
Jüri Allik ◽  
Tõnu Esko
Keyword(s):  
Educational Attainment ◽  
Personality Traits ◽  
Personality Trait ◽  
Factor Model ◽  
Five Factor Model ◽  
Molecular Genetic ◽  
Maximum Amount ◽  
Biological Processes ◽  
Psychological Traits ◽  
Polygenic Scores

Heritable variance in psychological traits may reflect genetic and biological processes that are not necessarily specific to these particular traits but pertain to a broader range of phenotypes. We tested the possibility that the personality domains of the five-factor model and their 30 facets, as rated by people themselves and their knowledgeable informants, reflect polygenic influences that have been previously associated with educational attainment. In a sample of more than 3,000 adult Estonians, education polygenic scores (EPSs), which are interpretable as estimates of molecular-genetic propensity for education, were correlated with various personality traits, particularly from the neuroticism and openness domains. The correlations of personality traits with phenotypic educational attainment closely mirrored their correlations with EPS. Moreover, EPS predicted an aggregate personality trait tailored to capture the maximum amount of variance in educational attainment almost as strongly as it predicted the attainment itself. We discuss possible interpretations and implications of these findings.

Women in Iranian Kurdistan: Patriarchy and the Quest for Empowerment

2021 ◽  
pp. 089124322110292
Author(s):  
Sahar Shakiba ◽  
Omid Ghaderzadeh ◽  
Valentine M. Moghadam
Keyword(s):  
Collective Action ◽  
Educational Attainment ◽  
Legal Status ◽  
Male Control ◽  
Gender Regime ◽  
Kurdish Women ◽  
The Family ◽  
Private And Public ◽  
And Gender ◽  
The City

Informed by sociological standpoint, intersectional, and gender regime theories, we examine perceptions of a diverse sample of Iranian Kurdish women in the city of Sanandaj about their legal status and social positions. We find perceptions of injustice, oppression, male control, and lack of opportunity associated with both the family and broader society. Kurdish women are socially located in structures and institutions of both private and public patriarchy. At the same time, their growing educational attainment and knowledge of possibilities for change enable them not only to articulate grievances but also to aspire to, and sometimes engage in, collective action for women’s rights. By focusing on an under-studied region, this article contributes to the wider literature on Kurdish women, underscores the continued salience of intersectional and standpoint approaches, and expands gender regime theorizing beyond Western cases.

scholarly journals Cognitive and brain development is independently influenced by socioeconomic status and polygenic scores for educational attainment

2020 ◽  
Vol 117 (22) ◽  
pp. 12411-12418 ◽  
Author(s):  
Nicholas Judd ◽  
Bruno Sauce ◽  
John Wiedenhoeft ◽  
Jeshua Tromp ◽  
Bader Chaarani ◽  
...  
Keyword(s):  
Socioeconomic Status ◽  
Educational Attainment ◽  
Brain Development ◽  
Surface Area ◽  
Brain Structure ◽  
Parental Education ◽  
Cortical Surface ◽  
Cortical Surface Area ◽  
Regional Association ◽  
Polygenic Scores

Genetic factors and socioeconomic status (SES) inequalities play a large role in educational attainment, and both have been associated with variations in brain structure and cognition. However, genetics and SES are correlated, and no prior study has assessed their neural associations independently. Here we used a polygenic score for educational attainment (EduYears-PGS), as well as SES, in a longitudinal study of 551 adolescents to tease apart genetic and environmental associations with brain development and cognition. Subjects received a structural MRI scan at ages 14 and 19. At both time points, they performed three working memory (WM) tasks. SES and EduYears-PGS were correlated (r= 0.27) and had both common and independent associations with brain structure and cognition. Specifically, lower SES was related to less total cortical surface area and lower WM. EduYears-PGS was also related to total cortical surface area, but in addition had a regional association with surface area in the right parietal lobe, a region related to nonverbal cognitive functions, including mathematics, spatial cognition, and WM. SES, but not EduYears-PGS, was related to a change in total cortical surface area from age 14 to 19. This study demonstrates a regional association of EduYears-PGS and the independent prediction of SES with cognitive function and brain development. It suggests that the SES inequalities, in particular parental education, are related to global aspects of cortical development, and exert a persistent influence on brain development during adolescence.

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