scholarly journals Economic evaluation of an online single-session intervention for depression in Kenyan adolescents.

2021 ◽  
Vol 89 (8) ◽  
pp. 657-667 ◽  
Author(s):  
Akash R. Wasil ◽  
Corinne N. Kacmarek ◽  
Tom L. Osborn ◽  
Emma H. Palermo ◽  
Robert J. DeRubeis ◽  
...  
2021 ◽  
Author(s):  
Michael Mullarkey ◽  
Mallory Dobias ◽  
Jenna Sung ◽  
Isaac Ahuvia ◽  
Jason Shumake ◽  
...  

BACKGROUND Anxiety is rising across the United States during the COVID-19 pandemic, and social distancing mandates preclude in-person mental healthcare. Anxiety is not necessarily pathological; however, increased worrying about COVID-19 shows links to more severe anxiety pathology. Greater perceived control over anxiety has predicted decreased anxiety pathology, including adaptive responses to uncontrollable stressors. Evidence suggests that no-therapist, single-session interventions can strengthen perceived control over emotions like anxiety; similar programs, if designed for the COVID-19 context, could hold substantial public health value. OBJECTIVE Our registered report tested whether a no-therapist, single-session online intervention adapted for the COVID-19 context could: 1) decrease generalized anxiety and increase perceived control over anxiety, versus a placebo intervention and 2) achieve this without decreasing social-distancing intentions. METHODS We tested these questions using a between-subjects design in a weighted-probability sample of U.S. adults (N=500). RESULTS We found no support for therapeutic or iatrogenic effects; effects on generalized anxiety were d = -0.06 (P = 0.48, CI [-0.27, 0.15]), effects on perceived control were d = 0.04 (P = 0.48, CI [-0.08, 0.16]), and effects on social-distancing intentions were d = -0.02 (P = 0.83, CI [-0.23, 0.19]). CONCLUSIONS Strengths of this study included a large, nationally representative sample and adherence to open science practices. Implications for scalable interventions are discussed. CLINICALTRIAL NCT04459455


2020 ◽  
Vol 9 (4) ◽  
pp. 386
Author(s):  
M Kishor ◽  
PK Ashwini ◽  
Jayadev Betkerur ◽  
Veeranna Shastry

2020 ◽  
Author(s):  
Akash R Wasil ◽  
Corinne Kacmarek ◽  
Tom L Osborn ◽  
Emma Palermo ◽  
Robert DeRubeis ◽  
...  

Objective: To evaluate the costs and cost-effectiveness of Shamiri-Digital, an online single-session intervention (SSI) for depression among Kenyan adolescents. Method: Data were drawn from a randomized clinical trial with n=103 Kenyan high school students (64% female, Mage=15.5). All students were eligible to participate, regardless of baseline depression symptomatology. We estimated delivery costs in 2020 US dollars from multiple perspectives. To account for uncertainty, we performed sensitivity analyses with different cost assumptions and definitions of effectiveness. Using number needed to treat (NNT) estimates, we also evaluated the cost required to achieve a clinically meaningful reduction in depressive symptoms.Results: In the base-case (the most realistic cost estimate), it cost US $3.57 per student to deliver Shamiri-Digital. Depending on the definition of clinically meaningful improvement, 7.1 to 9.7 students needed to receive the intervention for one student to experience a clinically meaningful improvement, which translated to a cost of US $25.35 to US $34.62 per student. Under a worst-case scenario (i.e., assuming the highest treatment cost and the strictest effectiveness definition), the cost to achieve clinically meaningful improvement was US $92.05 per student.Conclusions: Shamiri-Digital is a low-cost intervention for reducing depression symptomatology, especially relative to traditional psychotherapies. The public health benefit of empirically supported SSIs could be especially important in low-income countries, where funding for mental health care is most limited. Future research can compare the cost-effectiveness of online SSIs to higher-cost treatments and estimate the robustness of Shamiri-Digital’s effects over a longer time horizon.


10.2196/20513 ◽  
2020 ◽  
Vol 7 (6) ◽  
pp. e20513 ◽  
Author(s):  
Jessica Lee Schleider ◽  
Mallory Dobias ◽  
Jenna Sung ◽  
Emma Mumper ◽  
Michael C Mullarkey

Background Many youths with mental health needs are unable to access care. Single-session interventions (SSIs) have helped reduce youth psychopathology across multiple trials, promising to broaden access to effective, low-intensity supports. Online, self-guided SSIs may be uniquely scalable, particularly if they are freely available for as-needed use. However, the acceptability of online SSI and their efficacy have remained unexamined outside of controlled trials, and their practical utility is poorly understood. Objective We evaluated the perceived acceptability and proximal effects of Project YES (Youth Empowerment & Support), an open-access platform offering three online SSIs for youth internalizing distress. Methods After selecting one of three SSIs to complete, participants (ages 11-17 years) reported pre- and post-SSI levels of clinically relevant outcomes that SSIs may target (eg, hopelessness, self-hate) and perceived SSI acceptability. User-pattern variables, demographics, and depressive symptoms were collected to characterize youths engaging with YES. Results From September 2019 through March 2020, 694 youths accessed YES, 539 began, and 187 completed a 30-minute, self-guided SSI. SSI completers reported clinically elevated depressive symptoms, on average, and were diverse on several dimensions (53.75% non-white; 78.10% female; 43.23% sexual minorities). Regardless of SSI selection, completers reported pre- to post-program reductions in hopelessness (dav=0.53; dz=0.71), self-hate (dav=0.32; dz=0.61), perceived control (dav=0.60; dz=0.72) and agency (dav=0.39; dz=0.50). Youths rated all SSIs as acceptable (eg, enjoyable, likely to help peers). Conclusions Results support the perceived acceptability and utility of open-access, free-of-charge SSIs for youth experiencing internalizing distress. Trial Registration Open Science Framework; osf.io/e52p3


2020 ◽  
Author(s):  
Jessica Lee Schleider ◽  
Mallory Dobias ◽  
Jenna Sung ◽  
Emma Mumper ◽  
Michael C Mullarkey

BACKGROUND Many youths with mental health needs are unable to access care. Single-session interventions (SSIs) have helped reduce youth psychopathology across multiple trials, promising to broaden access to effective, low-intensity supports. Online, self-guided SSIs may be uniquely scalable, particularly if they are freely available for as-needed use. However, the acceptability of online SSI and their efficacy have remained unexamined outside of controlled trials, and their practical utility is poorly understood. OBJECTIVE We evaluated the perceived acceptability and proximal effects of Project YES (Youth Empowerment &amp; Support), an open-access platform offering three online SSIs for youth internalizing distress. METHODS After selecting one of three SSIs to complete, participants (ages 11-17 years) reported pre- and post-SSI levels of clinically relevant outcomes that SSIs may target (eg, hopelessness, self-hate) and perceived SSI acceptability. User-pattern variables, demographics, and depressive symptoms were collected to characterize youths engaging with YES. RESULTS From September 2019 through March 2020, 694 youths accessed YES, 539 began, and 187 completed a 30-minute, self-guided SSI. SSI completers reported clinically elevated depressive symptoms, on average, and were diverse on several dimensions (53.75% non-white; 78.10% female; 43.23% sexual minorities). Regardless of SSI selection, completers reported pre- to post-program reductions in hopelessness (<i>d</i><sub>av</sub>=0.53; <i>d</i><sub>z</sub>=0.71), self-hate (<i>d</i><sub>av</sub>=0.32; <i>d</i><sub>z</sub>=0.61), perceived control (<i>d</i><sub>av</sub>=0.60; <i>d</i><sub>z</sub>=0.72) and agency (<i>d</i><sub>av</sub>=0.39; <i>d</i><sub>z</sub>=0.50). Youths rated all SSIs as acceptable (eg, enjoyable, likely to help peers). CONCLUSIONS Results support the perceived acceptability and utility of open-access, free-of-charge SSIs for youth experiencing internalizing distress. CLINICALTRIAL Open Science Framework; osf.io/e52p3


2020 ◽  
Author(s):  
Akash Wasil ◽  
Madison Taylor ◽  
Rose Franzen ◽  
Joshua Steinberg ◽  
Robert DeRubeis

The COVID-19 outbreak has simultaneously increased the need for mental health services and decreased their availability. Brief online self-help interventions that can be completed in a single session could be especially helpful in improving access to care during the crisis. However, little is known about the uptake, acceptability, and perceived utility of these interventions outside of clinical trials in which participants are compensated. Here, we describe the development, deployment, acceptability ratings, and pre-post effects of a single-session intervention, the Common Elements Toolbox (COMET), adapted for the COVID-19 crisis to support graduate and professional students. Participants (n = 263), who were not compensated, were randomly assigned to two of three modules: behavioral activation, cognitive restructuring, and gratitude. Over one week, 263 individuals began and 189 individuals (72%) completed the intervention. Participants reported that the intervention modules were acceptable (93% endorsing), helpful (88%), engaging (86%), applicable to their lives (87%), and could help them manage COVID-related challenges (88%). Participants reported pre- to post-program improvements in secondary control (i.e., the belief that one can control their reactions to objective events; dav=0.36, dz=0.50, p&lt;0.001) and in the perceived negative impact of the COVID-19 crisis on their quality of life (dav=0.22, dz=0.25, p&lt;0.001). On average, differences in their perceived ability to handle lifestyle changes resulting from the pandemic were positive, but small and at the level of a nonsignificant trend (dav=0.13, dz=0.14, p=0.066). Our results highlight the acceptability and utility of an online intervention for supporting individuals through the COVID-19 crisis.


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