Health care contact and suicide risk documentation prior to suicide death: Results from the Army Study to Assess Risk and Resilience in Servicemembers (Army STARRS).

Abstract Background Postpartum depression is considered to be one of the most common health threats during pregnancy and postpartum, affecting not only the woman herself but also the offspring and the whole family system. Evidence for a conclusive etiopathological model with distinct risk and resilience factors is still broadly lacking. Therefore, the aim of the present study is to investigate numerous health-related markers to obtain greater insight into which biopsychosocial profiles render women more vulnerable to PPD or facilitate a healthy transition from pregnancy to postpartum. Methods The observational, longitudinal study aims to include a total of 288 physically healthy women, aged 20–45 years. A multitude of relevant parameters, of an (epi-) genetic, endocrinological, physiological and psychological nature, will be assessed over a period of 5 months, following the participants from the 3rd trimester until three months postpartum. Discussion The ultimate goal of the present study is to ameliorate mental health care during pregnancy and postpartum, by gaining a better understanding of the underlying biopsychosocial mechanisms that women undergo during the transition from pregnancy to postpartum.

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Prediction of Sex-Specific Suicide Risk Using Machine Learning and Single-Payer Health Care Registry Data From Denmark

JAMA Psychiatry ◽

10.1001/jamapsychiatry.2019.2905 ◽

2020 ◽

Vol 77 (1) ◽

pp. 25 ◽

Cited By ~ 12

Author(s):

Jaimie L. Gradus ◽

Anthony J. Rosellini ◽

Erzsébet Horváth-Puhó ◽

Amy E. Street ◽

Isaac Galatzer-Levy ◽

...

Keyword(s):

Machine Learning ◽

Health Care ◽

Suicide Risk ◽

Registry Data ◽

Single Payer

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Risk and Resilience Factors in Combat Military Health Care Providers

War and Family Life ◽

10.1007/978-3-319-21488-7_10 ◽

2015 ◽

pp. 181-193

Author(s):

Susanne W. Gibbons ◽

Edward J. Hickling

Keyword(s):

Health Care ◽

Health Care Providers ◽

Risk And Resilience ◽

Care Providers ◽

Military Health ◽

Military Health Care ◽

Resilience Factors

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Validation of an Electronic Health Record–Based Suicide Risk Prediction Modeling Approach Across Multiple Health Care Systems

JAMA Network Open ◽

10.1001/jamanetworkopen.2020.1262 ◽

2020 ◽

Vol 3 (3) ◽

pp. e201262 ◽

Cited By ~ 5

Author(s):

Yuval Barak-Corren ◽

Victor M. Castro ◽

Matthew K. Nock ◽

Kenneth D. Mandl ◽

Emily M. Madsen ◽

...

Keyword(s):

Health Care ◽

Electronic Health Record ◽

Risk Prediction ◽

Suicide Risk ◽

Health Care Systems ◽

Health Record ◽

Prediction Modeling ◽

Modeling Approach ◽

Care Systems ◽

Multiple Health

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Épidémiologie descriptive du risque suicidaire dans le système médical français de médecine générale: Descriptive epidemiology of suicide risk in a French general medicine health care system

The Canadian Journal of Psychiatry ◽

10.1177/0706743720961741 ◽

2020 ◽

pp. 070674372096174

Author(s):

J.-L. Ducher ◽

P.-M. Llorca ◽

S. Callahan ◽

I. de Chazeron

Keyword(s):

Health Care ◽

Health Care System ◽

Suicide Risk ◽

General Medicine ◽

Descriptive Epidemiology ◽

Médecine Générale ◽

Soins Primaires ◽

Care System

Objectif: La prévention du suicide passe certainement par une meilleure connaissance du risque suicidaire en soins primaires. Un certain nombre de publications internationales se sont intéressées à évaluer celui-ci, mais le plus souvent, auprès de populations particulières de consultants : patients jeunes, âgés, anhédoniques, dépressifs, etc. Notre étude analyse la prévalence du risque suicidaire chez des patients consultant en médecine générale quel que soit leur motif de consultation, somatique ou psychiatrique, leur pathologie ou leur âge. Méthode: Cette étude transversale a été menée auprès de patients adultes (inclusion de 827 sujets) venus consulter un panel de praticiens généralistes français sélectionnés de manière aléatoire. Ils ont rempli un auto-questionnaire validé (aRSD) évaluant leur risque suicidaire sur les 15 jours précédents et renseigné certaines données personnelles et professionnelles. Résultats: Les 757 dossiers (483 femmes; 274 hommes), totalement utilisables, montrent que près d’un quart des consultants (24,3 %) présente un risque suicidaire positif au cours des 15 jours précédant leur consultation et 6,3 %, un risque sévère (aRSD ≥ 7) avec idées et envie de passer à l’acte. Lorsque le motif de consultation est psychiatrique, 64,6 % de ces consultants ont un score aRSD positif. Une fois sur deux, il s’agit même d’un risque sévère. Conclusions: Ces données montrent l’importance de la prévalence du risque suicidaire en médecine générale. Elles confirment le rôle majeur que peuvent jouer les praticiens de soins primaires dans les actions de prévention du risque suicidaire. Elles montrent également l’apport que pourrait représenter l’utilisation d’un auto-questionnaire évaluant rapidement l’intentionnalité suicidaire dans le dépistage de celle-ci.

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Suicide Risk Documented During Veterans' Last Veterans Affairs Health Care Contacts Prior to Suicide

Suicide and Life-Threatening Behavior ◽

10.1111/sltb.12226 ◽

2016 ◽

Vol 46 (3) ◽

pp. 363-374 ◽

Cited By ~ 6

Author(s):

Lauren M. Denneson ◽

Anne E. Kovas ◽

Peter C. Britton ◽

Mark S. Kaplan ◽

Bentson H. McFarland ◽

...

Keyword(s):

Health Care ◽

Suicide Risk ◽

Veterans Affairs

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A Model for the Management of Suicidal Behaviour in Primary Care

European Psychiatry ◽

10.1016/s0924-9338(09)70618-2 ◽

2009 ◽

Vol 24 (S1) ◽

pp. 1-1

Author(s):

V. Voros ◽

P. Osvath ◽

S. Fekete

Keyword(s):

Primary Care ◽

Health Care ◽

Suicidal Behaviour ◽

Suicide Risk ◽

Health Care Services ◽

Warning Signs ◽

Health Concern ◽

Care Services ◽

Suicidal Patients ◽

Primary Care Professionals

Introduction:Although suicide rates are decreasing in most European countries, suicide is still a major health concern. Despite of the fact, that the vast majority of suicidal patients contacted with health care services before the suicidal act, the doctor-patient meeting is a necessary, but sometimes not sufficient way enough to prevent suicide. Most patients, who commit or attempt suicide, are not regarded as being at high immediate risk at their final contact with health care services.Aims and methods:Based on reviewing the relevant literature and on our previous studies we developed a brief, practical, clinical guideline, which may aid general practitioners and primary care professionals to assess suicide risk and also to manage these patients.Results:We introduce a model for an integrated, regional suicide prevention strategy, which includes recognition, risk assessment and also intervention. The main steps of our model are to recognize warning signs, explore crisis situation and/or psychopathologic symptoms, assess protective and risk factors, estimate suicide risk, plan intervention strategies, and finally manage suicidal patients through the different levels of intervention.Conclusion:In the management of suicidal behaviour the complex stress-diathesis model has to be adjusted by considering biological markers (mental disorders, personality traits) and psycho-social factors (crisis, negative life events, interpersonal conflicts). Only after the assessment of these factors primary care professionals, as ‘gatekeepers’ can manage suicidal patients effectively by using adequate psychopharmacotherapeutic and psychotherapeutic facilities in the recognition, treatment and prevention of suicidal behaviour.

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Rare protein coding variants implicate genes involved in risk of suicide death

10.1101/2020.01.10.902304 ◽

2020 ◽

Author(s):

Emily DiBlasi ◽

Andrey A. Shabalin ◽

Eric T. Monson ◽

Brooks R. Keeshin ◽

Amanda V. Bakian ◽

...

Keyword(s):

Genetic Risk ◽

Suicide Risk ◽

Rare Variants ◽

Sequence Data ◽

Control Sample ◽

Nucleotide Polymorphisms ◽

Protein Coding ◽

Health Crisis ◽

Suicide Death ◽

Prediction And Prevention

ABSTRACTSuicide death is a worldwide health crisis, claiming close to 800,000 lives per year. Recent evidence suggests that prediction and prevention challenges may be aided by discoveries of genetic risk factors. Here we focus on the role of rare (MAF <1%), putatively functional single nucleotide polymorphisms (SNPs) in suicide death using the large genetic resources available in the Utah Suicide Genetic Risk Study (USGRS). We conducted a single-variant association analysis of 30,377 rare putatively functional SNPs present on the PsychArray genotyping array in 2,672 USGRS suicides of non-Finnish European (NFE) ancestry and 51,583 publicly available NFE controls from gnomAD, with additional follow-up analyses using an independent control sample of 21,324 NFE controls from the Psychiatric Genomics Consortium. SNPs underwent rigorous quality control, and among SNPs meeting significance thresholds, we considered only those that were validated in sequence data. We identified five novel, high-impact, rare SNPs with significant associations with suicide death (SNAPC1, rs75418419; TNKS1BP1, rs143883793; ADGRF5, rs149197213; PER1, rs145053802; and ESS2, rs62223875). Both PER1 and SNAPC1 have other supporting gene-level evidence of suicide risk, and an association with bipolar disorder has been reported for PER1 and with schizophrenia for PER1, TNKS1BP1, and ESS2. Three genes (PER1, TNKS1BP1, and ADGRF5), with additional genes implicated by GWAS studies on suicidal behavior, showed significant enrichment in immune system, homeostatic and signal transduction processes. Pain, depression, and accidental trauma were the most prevalent phenotypes in electronic medical record data for the categories assessed. These findings suggest an important role for rare variants in suicide risk and provide new insights into the genetic architecture of suicide death. Furthermore, we demonstrate the added utility of careful assessment of genotyping arrays in rare variant discovery.

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