scholarly journals Interactive effects of ovarian steroid hormones on alcohol use and binge drinking across the menstrual cycle.

2017 ◽  
Vol 126 (8) ◽  
pp. 1104-1113 ◽  
Author(s):  
Michelle M. Martel ◽  
Tory Eisenlohr-Moul ◽  
Bethan Roberts
Keyword(s):  
Menstrual Cycle ◽  
Alcohol Use ◽  
Binge Drinking ◽  
Steroid Hormones ◽  
Interactive Effects ◽  
Ovarian Steroid

scholarly journals Differences in Free Estradiol and Sex Hormone-Binding Globulin in Women with and without Premenstrual Dysphoric Disorder

2008 ◽  
Vol 93 (1) ◽  
pp. 96-102 ◽  
Author(s):  
Susan Thys-Jacobs ◽  
Don McMahon ◽  
John P. Bilezikian
Keyword(s):  
Menstrual Cycle ◽  
Steroid Hormones ◽  
Luteal Phase ◽  
Premenstrual Dysphoric Disorder ◽  
Sex Hormone Binding Globulin ◽  
Self Assessment ◽  
Ovarian Steroid ◽  
Cross Sectional ◽  
Symptom Screening ◽  
Hormonal Evaluation

Abstract Context: Over the years, different hypotheses involving the ovarian steroid hormones have been proposed to explain the luteal phase occurrence of severe premenstrual syndrome symptoms. Although it had been strongly suspected that differences in the concentrations of the ovarian steroids may underlie the mood and psychological imbalance of this disorder, the evidence for this hypothesis has been inconsistent and remains controversial. Objective: Our objective was to measure the ovarian steroid hormones across the menstrual cycle in women with and without luteal phase symptoms consistent with premenstrual dysphoric disorder (PMDD). Design: We measured estradiol (E2), progesterone, and SHBG in women with and without PMDD using a cross-sectional and prospective experimental design. Participating women underwent 2-month self-assessment symptom screening and 1-month hormonal evaluation. Results: Overall means for LH, progesterone, E2, peak E2, and free E2 were not different between groups. Across the menstrual cycle, overall percent free E2 was significantly lower and SHBG significantly greater in the PMDD group compared with controls (1.39 ± 0.26 vs. 1.50 ± 0.28, P = 0.03; 61.4 ± 25.1 vs. 52.4 ± 21.3 nmol/liter, P = 0.046, respectively). During the luteal phase, free E2 was significantly lower in the PMDD group compared with controls (PMDD 7.6 ± 7.0 vs. controls 8.9 ± 8.4 pmol/liter; P = 0.032). For both follicular and luteal phases, SHBG was significantly higher in the PMDD group (follicular phase 60.5 ± 31.7 vs. 51.4 ± 38.2 nmol/liter, P = 0.047; luteal phase 65.1 ± 32.3 vs. 55.1 ± 38.9 nmol/liter, P =0.03). In both groups, SHBG significantly increased from the follicular to luteal phase. Conclusion: Luteal phase concentrations of free E2, percent free E2, and SHBG differ significantly between women with and without PMDD.

scholarly journals Are Changes in Personality Traits and Alcohol Use Associated? A Cohort Study Among Young Swiss Men

2020 ◽  
Vol 11 ◽  
Author(s):  
Gerhard Gmel ◽  
Simon Marmet ◽  
Joseph Studer ◽  
Matthias Wicki
Keyword(s):  
Cohort Study ◽  
Alcohol Use ◽  
Personality Traits ◽  
Binge Drinking ◽  
Sensation Seeking ◽  
Change Score ◽  
Effect Sizes ◽  
Direction Of Effects ◽  
Latent Change Score ◽  
Second Wave

Objective: It is well known that certain personality traits are associated with alcohol use. Because less is known about it, we wished to investigate whether changes in alcohol use were longitudinally associated with changes in personality and in which direction the influence or causation might flow.Methods: Data came from the self-reported questionnaire answers of 5,125 young men at two time points during the Cohort study on Substance Use Risk Factors (C-SURF). Their average ages were 20.0 and 25.4 years old at the first and second wave assessments, respectively. Four personality traits were measured: (a) aggression–hostility; (b) sociability; (c) neuroticism–anxiety; and (d) sensation seeking. Alcohol use was measured by volume (drinks per week) and binge drinking (about 60+ grams per occasion). Cross-lagged panel models and two-wave latent change score models were used.Results: Aggression–hostility, sensation seeking, and sociability were significantly and positively cross-sectionally associated with both alcohol use variables. Drinking volume and these three personality traits bidirectionally predicted each other. Binge drinking was bidirectionally associated with sensation-seeking only, whereas aggression–hostility and sociability only predicted binge drinking, but not vice versa. Changes in alcohol use were significantly positively associated with changes in aggression–hostility, sensation seeking, and sociability. Associations reached small Cohen's effect sizes for sociability and sensation seeking, but not for aggression–hostility. Associations with neuroticism–anxiety were mostly not significant.Conclusion: The direction of effects confirmed findings from other studies, and the association between changes in personality and alcohol use support the idea that prevention programs should simultaneously target both.

CHANGES IN THE CONCENTRATION OF PITUITARY AND STEROID HORMONES IN THE FOLLICULAR FLUID OF HUMAN GRAAFIAN FOLLICLES THROUGHOUT THE MENSTRUAL CYCLE

1975 ◽  
Vol 64 (3) ◽  
pp. 555-571 ◽  
Author(s):  
K. P. McNATTY ◽  
W. M. HUNTER ◽  
A. S. McNEILLY ◽  
R. S. SAWERS
Keyword(s):  
Menstrual Cycle ◽  
Steroid Hormones ◽  
Follicular Fluid ◽  
Follicle Stimulating Hormone ◽  
Secretory Activity ◽  
Follicular Phase ◽  
Hormonal Changes ◽  
Peripheral Plasma ◽  
Before And After ◽  
Late Follicular Phase

SUMMARY The concentrations of FSH, LH, prolactin, oestradiol and progesterone were measured in peripheral plasma and follicular fluid of women throughout the menstrual cycle. With the exception of prolactin, concentrations of pituitary and steroid hormones in follicular fluid correlated with those in peripheral plasma. Follicle-stimulating hormone was present in a greater number of small follicles ( < 8 mm) during or just after the peaks of FSH in peripheral plasma. During the mid-follicular phase the concentration of both FSH and oestradiol in fluid from large follicles ( ≥ 8 mm) was high. During the late follicular phase the large follicles ( ≥ 8 mm) contained high amounts of progesterone in addition to oestradiol, low physiological levels of prolactin, and concentrations of LH and FSH about 30 and 60% respectively of those found in plasma. By contrast no large 'active' follicles ( ≥ 8 mm) were found during the luteal phase although many contained both LH and FSH. Luteinizing hormone was present in a proportion of small follicles ( < 8 mm) during the late follicular and early luteal but not at other stages of the menstrual cycle. It is suggested that a precise sequence of hormonal changes occur within the microenvironment of the developing Graafian follicle; the order in which they occur may be of considerable importance for the growth of that follicle and secretory activity of the granulosa cells both before and after ovulation.

Exercise training effects on premenstrual distress and ovarian steroid hormones

2006 ◽  
Vol 99 (1) ◽  
pp. 27-37 ◽  
Author(s):  
Jacqueline L. Stoddard ◽  
Clyde W. Dent ◽  
Lisa Shames ◽  
Leslie Bernstein
Keyword(s):  
Exercise Training ◽  
Steroid Hormones ◽  
Training Effects ◽  
Ovarian Steroid ◽  
Premenstrual Distress
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