scholarly journals Bulimic symptom onset in young girls: A longitudinal trajectory analysis.

2015 ◽  
Vol 124 (4) ◽  
pp. 1003-1013 ◽  
Author(s):  
Carolyn M. Pearson ◽  
Gregory T. Smith
Keyword(s):  
Symptom Onset ◽  
Trajectory Analysis ◽  
Young Girls ◽  
Bulimic Symptom

Effect of motor symptom onset asymmetry on facial expressivity

2008 ◽  
Author(s):  
Anne N. Nisenzon ◽  
Utaka Springer ◽  
Ann Mikos ◽  
Michael S. Okun ◽  
Hubert Fernandez ◽  
...  
Keyword(s):  
Symptom Onset ◽  
Motor Symptom ◽  
Facial Expressivity

No Country For Young Girls?

2008 ◽  
Author(s):  
Nupur Basu ◽  
Keyword(s):  
Young Girls

A Fused Thiophene-S,S-Dioxide-Based Super-Photostable Fluorescent Marker for Lipid Droplets

2020 ◽  
Author(s):  
Masayasu Taki ◽  
Keiji Kajiwara ◽  
Eriko Yamaguchi ◽  
Yoshikatsu Sato ◽  
Shigehiro Yamaguchi
Keyword(s):  
Small Molecules ◽  
Lipid Droplets ◽  
Trajectory Analysis ◽  
Super Resolution ◽  
Fluorescent Marker ◽  
Selective Staining ◽  
Fluorescent Markers ◽  
Biological Studies ◽  
Particle Level

Lipid droplets (LDs) are essential organelle in most eukaryotes, and tracking intracellular LDs dynamics using synthetic small molecules is crucial for biological studies. However, only a limited number of fluorescent markers that satisfy all requirements, such as the selective staining of LDs, high photostability, and sufficient biocompatibility, have been developed. Herein, we report a series of donor-p-acceptor dyes based on the thiophene-containing fused polycyclic scaffold [1]benzothieno[3,2-<i>b</i>][1]benzothiophene (BTBT), in which either or both thiophene rings are oxidized into thiophene-<i>S</i>,<i>S</i>-dioxide to form an electron-accepting building block. Among these dyes, LAQ1 satisfied all the aforementioned requirements, and allowed us capturing ultra-small LDs on the endoplasmic reticulum (ER) membrane by stimulation emission depletion (STED) microscopy with a super-resolution below the diffraction limit of light. Moreover, the extremely high photostability of LAQ1 enabled recording the lipolysis of LDs and the concomitant lipogenesis as well as long-term trajectory analysis of micro LDs at the single particle level in living cells.

Understanding quality of life and treatment history of patients with Bertolotti syndrome compared with lumbosacral radiculopathy

2019 ◽  
Vol 31 (2) ◽  
pp. 222-228 ◽  
Author(s):  
Joshua L. Golubovsky ◽  
Arbaz Momin ◽  
Nicolas R. Thompson ◽  
Michael P. Steinmetz
Keyword(s):  
Quality Of Life ◽  
Mental Health ◽  
Propensity Score ◽  
Disc Herniation ◽  
Symptom Onset ◽  
Patient Reported Outcomes ◽  
Lumbosacral Radiculopathy ◽  
Patient Reported ◽  
Age And Sex

OBJECTIVEBertolotti syndrome is a rare spinal condition that causes low-back pain due to a lumbosacral transitional vertebra (LSTV), which is a pseudoarticulation between the fifth lumbar transverse process and the sacral ala. Bertolotti syndrome patients are rarely studied, particularly with regard to their quality of life. This study aimed to examine the quality of life and prior treatments in patients with Bertolotti syndrome at first presentation to the authors’ center in comparison with those with lumbosacral radiculopathy.METHODSThis study was a retrospective cohort analysis of patients with Bertolotti syndrome and lumbosacral radiculopathy due to disc herniation seen at the authors’ institution’s spine center from 2005 through 2018. Diagnoses were confirmed with provider notes and imaging. Variables collected included demographics, diagnostic history, prior treatment, patient-reported quality of life metrics, and whether or not they underwent surgery at the authors’ institution. Propensity score matching by age and sex was used to match lumbosacral radiculopathy patients to Bertolotti syndrome patients. Group comparisons were made using t-tests, Fisher’s exact test, Mann-Whitney U-tests, Cox proportional hazards models, and linear regression models where variables found to be different at the univariate level were included as covariates.RESULTSThe final cohort included 22 patients with Bertolotti syndrome who had patient-reported outcomes data available and 46 propensity score–matched patients who had confirmed radiculopathy due to disc herniation. The authors found that Bertolotti syndrome patients had significantly more prior epidural steroid injections (ESIs) and a longer time from symptom onset to their first visit. Univariate analysis showed that Bertolotti syndrome patients had significantly worse Patient-Reported Outcomes Measurement Information System (PROMIS) mental health T-scores. Adjustment for prior ESIs and time from symptom onset revealed that Bertolotti syndrome patients also had significantly worse PROMIS physical health T-scores. Time to surgery and other quality of life metrics did not differ between groups.CONCLUSIONSPatients with Bertolotti syndrome undergo significantly longer workup and more ESIs and have worse physical and mental health scores than age- and sex-matched patients with lumbosacral radiculopathy. However, both groups of patients had mild depression and clinically meaningful reduction in their quality of life according to all instruments. This study shows that Bertolotti syndrome patients have a condition that affects them potentially more significantly than those with lumbosacral radiculopathy, and increased attention should be paid to these patients to improve their workup, diagnosis, and treatment.

Union Formation and Onset of Sex among Young Girls in Kachia Local Government Area of Kaduna State

2010 ◽  
Vol 8 (1) ◽  
Author(s):  
John Gambo LAAH
Keyword(s):  
Local Government ◽  
Young Women ◽  
Sexual Debut ◽  
State Level ◽  
Local Government Area ◽  
Group Discussions ◽  
Chi Square ◽  
Young Girls ◽  
Significant Relationships ◽  
Women’S Sexual Health

Analysis of marriage intentions and sexual experiences of young women are necessary in drawing up state-level and countrywide policies that address young women’s sexual health needs. This paper draws on results of a study utilizing structured questionnaires and Focus Group Discussions (FGDs) to examine marriage and sexual debut among young girls in Kachia Local Government Area of Kaduna State. A total of 862 questionnaires were administered among young women within the age of 11 and 25 years. The information from the questionnaire was analysed using the Chi-square (X2) test to assess bivariate association between ever had sex and age at first sex and some socio-demographic characteristics of young girls. The study hypothesised that ever had sex, age at first sexual encounter and age at marriage do not differ by some sociodemographic characteristics of women. The results of the analysis revealed that the majority (70%) of the respondents have ever had sex and that 9.6% have ever married. The X2 test revealed that there are significant relationships between ever had sex and age of respondents (X2, df=4, p=0.001)), marital status (X2, df=4, p=0.001) and level of education (X2, df=6, p=0.001). There was, however, no statistical differences between ever had sex and religion and residence. The paper recommended a multifaceted programme to address the needs of young girls in Kachia LGA.

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