scholarly journals Anhedonia, depressed mood, and smoking cessation outcome.

2014 ◽  
Vol 82 (1) ◽  
pp. 122-129 ◽  
Author(s):  
Adam M. Leventhal ◽  
Megan E. Piper ◽  
Sandra J. Japuntich ◽  
Timothy B. Baker ◽  
Jessica W. Cook
Author(s):  
Cheng-Chien Lai ◽  
Wei-Hsin Huang ◽  
Betty Chia-Chen Chang ◽  
Lee-Ching Hwang

Predictors for success in smoking cessation have been studied, but a prediction model capable of providing a success rate for each patient attempting to quit smoking is still lacking. The aim of this study is to develop prediction models using machine learning algorithms to predict the outcome of smoking cessation. Data was acquired from patients underwent smoking cessation program at one medical center in Northern Taiwan. A total of 4875 enrollments fulfilled our inclusion criteria. Models with artificial neural network (ANN), support vector machine (SVM), random forest (RF), logistic regression (LoR), k-nearest neighbor (KNN), classification and regression tree (CART), and naïve Bayes (NB) were trained to predict the final smoking status of the patients in a six-month period. Sensitivity, specificity, accuracy, and area under receiver operating characteristic (ROC) curve (AUC or ROC value) were used to determine the performance of the models. We adopted the ANN model which reached a slightly better performance, with a sensitivity of 0.704, a specificity of 0.567, an accuracy of 0.640, and an ROC value of 0.660 (95% confidence interval (CI): 0.617–0.702) for prediction in smoking cessation outcome. A predictive model for smoking cessation was constructed. The model could aid in providing the predicted success rate for all smokers. It also had the potential to achieve personalized and precision medicine for treatment of smoking cessation.


2018 ◽  
Vol 21 (8) ◽  
pp. 1135-1139 ◽  
Author(s):  
Grace Crawford ◽  
Jessica Weisbrot ◽  
Joseph Bastian ◽  
Alex Flitter ◽  
Nancy C Jao ◽  
...  

Abstract Introduction The degree to which smokers adhere to pharmacotherapy predicts treatment success. The development of interventions to increase adherence requires identification of predictors of treatment adherence, particularly among specific clinical populations. Methods Using data from a 12-week open-label phase of a clinical trial of varenicline for tobacco dependence among cancer patients (N = 207), we examined: (1) the relationship between self-reported varenicline adherence and verified smoking cessation and (2) demographic and disease-related variables, and early changes in cognition, affect, withdrawal, the reinforcing effects of smoking, and medication side effects, as correlates of varenicline adherence. Results At the end of 12 weeks, 35% of the sample had quit smoking and 52% reported taking ≥80% of varenicline. Varenicline adherence was associated with cessation (p < .001): 58% of participants who were adherent had quit smoking versus 11% of those who were not. Participants who experienced early reductions in depressed mood and satisfaction from smoking and experienced an increase in the toxic effects of smoking, showed greater varenicline adherence (p < .05); the relationship between greater adherence and improved cognition, reduced craving, and reduced sleep problems and vomiting approached significance (p < .10). Conclusions Among cancer patients treated for tobacco dependence with varenicline, adherence is associated with smoking cessation. Initial changes in depressed mood and the reinforcing effects of smoking are predictive of adherence. Implications The benefits of varenicline for treating tobacco dependence among cancer patients may depend upon boosting adherence by addressing early signs of depression and reducing the reinforcing dimensions of cigarettes.


2019 ◽  
Vol 14 (2) ◽  
pp. 408-415
Author(s):  
Chao Wang ◽  
Zhujing Shen ◽  
Peiyu Huang ◽  
Wei Qian ◽  
Cheng Zhou ◽  
...  

2001 ◽  
Vol 69 (4) ◽  
pp. 604-613 ◽  
Author(s):  
Kenneth A. Perkins ◽  
Marsha D. Marcus ◽  
Michele D. Levine ◽  
Delia D'Amico ◽  
Amy Miller ◽  
...  

1995 ◽  
Vol 24 (2) ◽  
pp. 194-200 ◽  
Author(s):  
D.L. Franke ◽  
B.N. Leistikow ◽  
K.P. Offord ◽  
L. Schmidt ◽  
R.D. Hurt

1996 ◽  
Author(s):  
Arie Dijkstra ◽  
Hein De Vries ◽  
Martijntje Bakker

1994 ◽  
Vol 23 (3) ◽  
pp. 335-344 ◽  
Author(s):  
C.L. Rohren ◽  
I.T. Croghan ◽  
R.D. Hurt ◽  
K.P. Offord ◽  
Z. Marusic ◽  
...  

2003 ◽  
Vol 71 (4) ◽  
pp. 657-663 ◽  
Author(s):  
Brian Hitsman ◽  
Belinda Borrelli ◽  
Dennis E. McChargue ◽  
Bonnie Spring ◽  
Raymond Niaura

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