scholarly journals Combining imagination and reason in the treatment of depression: A randomized controlled trial of internet-based cognitive-bias modification and internet-CBT for depression.

2013 ◽  
Vol 81 (5) ◽  
pp. 793-799 ◽  
Author(s):  
Alishia D. Williams ◽  
Simon E. Blackwell ◽  
Anna Mackenzie ◽  
Emily A. Holmes ◽  
Gavin Andrews
Keyword(s):  
Randomized Controlled Trial ◽  
Cognitive Bias ◽  
Controlled Trial ◽  
Cognitive Bias Modification ◽  
Randomized Controlled ◽  
Treatment Of Depression ◽  
Bias Modification

The Effects of Modifying Dysfunctional Appraisals in Posttraumatic Stress Disorder Using a Form of Cognitive Bias Modification: Results of a Randomized Controlled Trial in an Inpatient Setting

2021 ◽  
pp. 1-17
Author(s):  
Marcella L. Woud ◽  
Simon E. Blackwell ◽  
Lorika Shkreli ◽  
Felix Würtz ◽  
Jan Christopher Cwik ◽  
...  
Keyword(s):  
Posttraumatic Stress Disorder ◽  
Randomized Controlled Trial ◽  
Cognitive Bias ◽  
Stress Disorder ◽  
Controlled Trial ◽  
Cognitive Bias Modification ◽  
Ptsd Symptoms ◽  
Randomized Controlled ◽  
Scenario Task ◽  
Bias Modification

Introduction: Dysfunctional appraisals about traumatic events and their sequelae are a key mechanism in posttraumatic stress disorder (PTSD). Experimental studies have shown that a computerized cognitive training, cognitive bias modification for appraisals (CBM-APP), can modify dysfunctional appraisals and reduce analogue trauma symptoms amongst healthy and subclinical volunteers. Objective: We aimed to test whether CBM-APP could reduce dysfunctional appraisals related to trauma reactions in PTSD patients, and whether this would lead to improvements in PTSD symptoms. Methods: We compared CBM-APP to sham training in a parallel-arm proof-of-principle double-blind randomized controlled trial amongst 80 PTSD patients admitted to an inpatient clinic. Both arms comprised a training schedule of 8 sessions over a 2-week period and were completed as an adjunct to the standard treatment programme. Results: In intention-to-treat analyses, participants receiving CBM-APP showed a greater reduction in dysfunctional appraisals on a scenario task from pre- to posttraining (primary outcome) assessments, compared to those receiving sham training (d = 1.30, 95% CI 0.82–1.80), with between-group differences also found on the Posttraumatic Cognitions Inventory (PTCI; d = 0.85, 95% CI 0.39–1.32) and the PTSD Checklist for DSM-5 (PCL-5; d = 0.68, 95% CI 0.23–1.14), but not for long-term cortisol concentrations (d = 0.25, 95% CI –0.28 to 0.78). Reductions in dysfunctional appraisals assessed via the scenario task correlated with reductions on the PTCI, PCL-5, and hair cortisol concentrations from pre- to posttraining time points. Conclusions: Results support dysfunctional appraisals as a modifiable cognitive mechanism, and that their proximal modification transfers to downstream PTSD symptoms. These findings could open new avenues for improving present therapeutic approaches.

scholarly journals The effects of Cognitive Bias Modification training and oxytocin administration on trust in maternal support: study protocol for a randomized controlled trial

Trials ◽  
2017 ◽  
Vol 18 (1) ◽  
Author(s):  
Martine W. F. T. Verhees ◽  
Eva Ceulemans ◽  
Marian J. Bakermans-Kranenburg ◽  
Marinus H. van IJzendoorn ◽  
Simon de Winter ◽  
...  
Keyword(s):  
Randomized Controlled Trial ◽  
Study Protocol ◽  
Cognitive Bias ◽  
Controlled Trial ◽  
Cognitive Bias Modification ◽  
Maternal Support ◽  
Randomized Controlled ◽  
Bias Modification

scholarly journals Combining oxytocin and cognitive bias modification training in a randomized controlled trial: Effects on trust in maternal support

2020 ◽  
Vol 66 ◽  
pp. 101514
Author(s):  
Martine W.F.T. Verhees ◽  
Marinus H. van IJzendoorn ◽  
Marian J. Bakermans-Kranenburg ◽  
Eva Ceulemans ◽  
Simon de Winter ◽  
...  
Keyword(s):  
Randomized Controlled Trial ◽  
Cognitive Bias ◽  
Controlled Trial ◽  
Cognitive Bias Modification ◽  
Maternal Support ◽  
Randomized Controlled ◽  
Bias Modification
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