scholarly journals A randomized clinical trial comparing an acceptance-based behavior therapy to applied relaxation for generalized anxiety disorder.

2013 ◽  
Vol 81 (5) ◽  
pp. 761-773 ◽  
Author(s):  
Sarah A. Hayes-Skelton ◽  
Lizabeth Roemer ◽  
Susan M. Orsillo
Keyword(s):  
Clinical Trial ◽  
Anxiety Disorder ◽  
Randomized Clinical Trial ◽  
Generalized Anxiety Disorder ◽  
Behavior Therapy ◽  
Generalized Anxiety ◽  
Applied Relaxation

Cognitive Behavior Therapy Targeting Intolerance of Uncertainty Versus Selective Serotonin Reuptake Inhibitor for Generalized Anxiety Disorder: A Randomized Clinical Trial

2021 ◽  
pp. 1-13 ◽  
Author(s):  
Mehdi Zemestani ◽  
Negar Beheshti ◽  
Farzin Rezaei ◽  
Colin van der Heiden ◽  
Philip C. Kendall
Keyword(s):  
Clinical Trial ◽  
Anxiety Disorder ◽  
Generalized Anxiety Disorder ◽  
Behavior Therapy ◽  
Cognitive Behavior Therapy ◽  
Serotonin Reuptake ◽  
Intolerance Of Uncertainty ◽  
Selective Serotonin ◽  
Generalized Anxiety ◽  
Cognitive Behavior

Abstract Given the high prevalence and adverse outcomes associated with generalized anxiety disorder (GAD), development and expansion of effective treatment modalities are important. The present study compared the effectiveness of cognitive behavior therapy targeting intolerance of uncertainty (CBT-IU) and selective serotonin reuptake inhibitors (SSRIs) for treating GAD. A total of 30 Iranian patients with GAD (Mage = 25.16 ± 6.73) were randomised to receive either CBT-IU (n = 15) or SSRI (n = 15). Measures included the Structured Clinical Interview for DSM-5 (SCID-5), Penn State Worry Questionnaire (PSWQ), Why Worry-II (WW-II), Intolerance of Uncertainty Scale (IUS), and Negative Problem Orientation Questionnaire (NPOQ). Repeated measures analysis of variance tested differential treatment outcomes. The results of intention-to-treat (ITT) analysis indicated that although both CBT-IU and SSRI were effective treatments for GAD, CBT-IU produced significantly better results than SSRI at post-treatment. This clinical trial provides preliminary cross-cultural support for the treatment of GAD using CBT-IU, with findings suggesting that this non-medication intervention reduces GAD symptoms.

Transcranial direct current stimulation for the treatment of generalized anxiety disorder: A randomized clinical trial

2019 ◽  
Vol 259 ◽  
pp. 31-37 ◽  
Author(s):  
Ana Lucia de Lima ◽  
Francisco Moisés Azevedo Braga ◽  
Rodrigo Maciel Medeiros da Costa ◽  
Elihab Pereira Gomes ◽  
André Russowsky Brunoni ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Anxiety Disorder ◽  
Randomized Clinical Trial ◽  
Generalized Anxiety Disorder ◽  
Direct Current ◽  
Transcranial Direct Current Stimulation ◽  
Generalized Anxiety ◽  
Direct Current Stimulation

scholarly journals Predictors of change in quality of life in older adults with generalized anxiety disorder

2014 ◽  
Vol 27 (7) ◽  
pp. 1207-1215 ◽  
Author(s):  
Srijana Shrestha ◽  
Melinda A. Stanley ◽  
Nancy L. Wilson ◽  
Jeffrey A. Cully ◽  
Mark E. Kunik ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Social Support ◽  
Older Adults ◽  
Clinical Trial ◽  
Anxiety Disorder ◽  
Randomized Clinical Trial ◽  
Generalized Anxiety Disorder ◽  
Generalized Anxiety ◽  
Over Time

ABSTRACTBackground:Quality of life (QOL) is lower in older adults with generalized anxiety disorder (GAD). QOL generally improves following cognitive-behavioral treatment for GAD. Little is known, however, about additional variables predicting changes in QOL in older adults with GAD. This study examined predictors of change in QOL among older participants in a randomized clinical trial of cognitive behavioral therapy (CBT) for GAD, relative to enhanced usual care (EUC).Methods:Hierarchical multilevel mixed-model analyses were used to examine inter-individual and intra-individual factors that predicted QOL over time. Predictors were categorized into treatment, personal and clinical characteristics.Results:QOL improved over time, and there was significant variability between participants in change in QOL. Controlling for treatment condition, baseline general self-efficacy, baseline social support, within-person variation in worry and depression and average levels of depression across different time points predicted changes in QOL.Conclusions:QOL has increasingly been used as an outcome measure in treatment outcome studies to focus on overall improvement in functioning. Attention to improvement in symptoms of depression and worry, along with psychosocial variables, such as social support and self-efficacy, may help improve QOL in older adults with GAD.This study was a secondary study of data from a randomized clinical trial (NCT00308724) registered with clinical.trials.gov.

scholarly journals Long-term chamomile (Matricaria chamomilla L.) treatment for generalized anxiety disorder: A randomized clinical trial

Phytomedicine ◽  
2016 ◽  
Vol 23 (14) ◽  
pp. 1735-1742 ◽  
Author(s):  
Jun J. Mao ◽  
Sharon X. Xie ◽  
John R. Keefe ◽  
Irene Soeller ◽  
Qing S. Li ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Anxiety Disorder ◽  
Randomized Clinical Trial ◽  
Generalized Anxiety Disorder ◽  
Generalized Anxiety ◽  
Matricaria Chamomilla
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