The motive to drink due to social anxiety and its relation to hazardous alcohol use.

2013 ◽  
Vol 27 (3) ◽  
pp. 806-813 ◽  
Author(s):  
Barbara Cludius ◽  
Stephan Stevens ◽  
Trisha Bantin ◽  
Alexander L. Gerlach ◽  
Christiane Hermann
2021 ◽  
Author(s):  
Katrina Prior ◽  
Elske Salemink ◽  
Reinout W Wiers ◽  
Bethany A Teachman ◽  
Monique Piggott ◽  
...  

BACKGROUND Alcohol use and anxiety disorders commonly co-occur, resulting in a more severe clinical presentation and poorer response to single-disorder treatments. Research has shown that Approach Bias Modification (ApBM) and Interpretation Bias Modification (IBM) cognitive re-training interventions can be efficacious adjunctive treatments that improve outcomes for alcohol use and social anxiety symptoms, respectively. However, the acceptability, feasibility and clinical utility of combining ApBM and IBM programs to optimise standard treatments among comorbid samples is unknown. It is also unclear as to whether integrating ApBM and IBM within each training session, or alternating them between each session, is more acceptable and efficacious. OBJECTIVE This paper describes the study protocol for a randomized controlled pilot trial investigating the feasibility, acceptability, and preliminary efficacy of the ‘Re-Train Your Brain’ intervention – an adjunct web-based ApBM+IBM program – among a clinical sample of emerging adults with hazardous alcohol use and social anxiety. METHODS The study involves a 3-arm randomized controlled pilot trial in which treatment-seeking emerging adults (18-30 years) with co-occurring hazardous alcohol use and social anxiety disorder symptoms will be individually randomized to receive: (1) the Re-Train Your Brain ‘integrated’ program, delivered with 10 bi-weekly sessions focusing on both social anxiety and alcohol each week (50:50 ratio), plus treatment as usual (TAU i.e., the model of care provided in accordance with standard practice at their service; n=30); (2) the Re-Train Your Brain ‘alternating’ program, delivered with 10 bi-weekly sessions focusing on social anxiety one week and alcohol the next week in an alternating pattern, plus TAU (n=30); or (3) TAU only (n=30). Primary outcomes include feasibility (uptake, follow-up rates, treatment adherence, attrition, adverse events) and acceptability (system usability, client satisfaction, user experience, training format preference). Secondary efficacy outcomes include changes in alcohol approach and interpretation biases, social anxiety symptoms, and alcohol use (e.g., average drinks per day, binge-drinking, alcohol use motives, severity of alcohol dependence, alcohol craving). The primary endpoint will be post-treatment (6 weeks post-baseline), with a secondary endpoint at 3 months post-baseline. Descriptive statistics will be conducted for primary outcomes, while intention-to-treat multi-level mixed effects analysis for repeated measures will be performed for secondary outcomes. RESULTS The study is funded from 2019―2023 by Australian Rotary Health. Recruitment is expected to be complete by mid―late 2022, with follow-ups completed by early 2023. CONCLUSIONS The study will be the first to evaluate whether an ApBM+IBM program is acceptable to treatment-seeking emerging adults and whether it is feasible to deliver it online, in settings where it will ultimately be used (e.g., at home). The findings will broaden our understanding of the types of programs that emerging adults will engage with, and whether there is preliminary evidence of it being an efficacious treatment option for this comorbidity. CLINICALTRIAL Australian New Zealand Clinical Trials Registry (ANZCTR) ACTRN12620001273976


Author(s):  
Lisa R. Miller-Matero ◽  
Julia Orlovskaia ◽  
Leah M. Hecht ◽  
Jordan M. Braciszeweski ◽  
Kellie M. Martens ◽  
...  

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Janja Jazbar ◽  
Igor Locatelli ◽  
Mitja Kos

Abstract Background Understanding potentially modifiable factors that influence the risk of frailty is a key concern for the management of this urgent contemporary public health challenge. This study evaluates the association between the use of various medications or alcohol and the incidence of frailty among older adults. Methods This study was a retrospective cohort study on older adults (≥ 65 years) using data from the longitudinal Survey of Health, Ageing and Retirement in Europe (SHARE survey, 28 countries). Medication use was measured as taking several different groups of medications. Alcohol use was assessed with SHARE questions corresponding to AUDIT-C. The outcome measure was the incidence of frailty after two years, defined by frailty index (FI) and frailty phenotype (FP). A multiple logistic regression model was used to evaluate the association with adjustment for several potential confounding factors. Results Of the 14,665 FI-population participants, 1800 (12.3%) developed frailty within two years. Of the 8133 FP-population participants, 2798 (34.4%) developed pre-frailty and 247 (3.0%) developed frailty within two years of baseline. After adjustment for potential confounding variables, non-hazardous alcohol use (adjusted OR; 95% CI for the FI-population: 0.68; 0.60–0.77) and hazardous alcohol use (0.80; 0.68–0.93) are associated with lower incidence of frailty compared to no alcohol use. The odds of frailty are increased when taking medications; the largest effect size was observed in older adults taking medication for chronic bronchitis (adjusted OR; 95% CI for the FI-population: 2.45; 1.87–3.22), joint pain and other pain medication (2.26; 2.00–2.54), medication for coronary and other heart disease (1.72; 1.52–1.96), medication for diabetes (1.69; 1.46–1.96), and medication for anxiety, depression and sleep problems (1.56; 1.33–1.84). Additionally, the risk of frailty was increased with stroke, Parkinson’s disease and dementia. Conclusions Taking certain groups of medication was associated with increased incidence of frailty and pre-frailty, which might be due to either medication use or the underlying disease. Alcohol use was associated with a lower risk of pre-frailty and frailty compared to no alcohol use, which might be due to reverse causality or residual confounding. There was no significant interaction effect between medication groups and alcohol use on frailty incidence.


2000 ◽  
Vol 19 (3) ◽  
pp. 291-298 ◽  
Author(s):  
G. K. Hulse ◽  
J. B. Saunders ◽  
R. M. Roydhouse ◽  
T. R. Stockwell ◽  
M. R. Basso

Alcohol ◽  
2017 ◽  
Vol 60 ◽  
pp. 219
Author(s):  
T.H. McKim ◽  
G. Guo ◽  
S. Lane ◽  
M.H. Parrish ◽  
C.T. Smith ◽  
...  

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