scholarly journals Predictors of patient cognitive therapy skills and symptom change in two randomized clinical trials: The role of therapist adherence and the therapeutic alliance.

2012 ◽  
Vol 80 (3) ◽  
pp. 373-381 ◽  
Author(s):  
Christian A. Webb ◽  
Robert J. DeRubeis ◽  
Sona Dimidjian ◽  
Steven D. Hollon ◽  
Jay D. Amsterdam ◽  
...  
Keyword(s):  
Clinical Trials ◽  
Therapeutic Alliance ◽  
Cognitive Therapy ◽  
Randomized Clinical Trials ◽  
Symptom Change ◽  
Therapist Adherence

scholarly journals COVID-19: Role of Nutrition and Supplementation

Nutrients ◽  
2021 ◽  
Vol 13 (3) ◽  
pp. 976
Author(s):  
Fiorenzo Moscatelli ◽  
Francesco Sessa ◽  
Anna Valenzano ◽  
Rita Polito ◽  
Vincenzo Monda ◽  
...  
Keyword(s):  
Clinical Trials ◽  
Randomized Clinical Trials ◽  
Viral Infections ◽  
Overweight And Obesity ◽  
Shortness Of Breath ◽  
Nutritional Interventions ◽  
The World ◽  
Diet Regimen ◽  
Specific Diet

At the end of 2019, a new coronavirus (COVID-19) appeared on the world scene, which mainly affects the respiratory system, causing pneumonia and multi-organ failure, and, although it starts with common symptoms such as shortness of breath and fever, in about 2–3% of cases it leads to death. Unfortunately, to date, no specific treatments have been found for the cure of this virus and, therefore, it is advisable to implement all possible strategies in order to prevent infection. In this context, it is important to better define the role of all behaviors, in particular nutrition, in order to establish whether these can both prevent infection and improve the outcome of the disease in patients with COVID-19. In the literature, it is widely shown that states of malnutrition, overweight, and obesity negatively affect the immune system, leading to viral infections, and several studies have shown that nutritional interventions can act as immunostimulators, helping to prevent viral infections. Even if several measures, such as the assumption of a specific diet regimen, the use of dietary supplements, and other similar interventions, are promising for the prevention, management, and recovery of COVID-19 patients, it is important to highlight that strong data from randomized clinical trials are needed to support any such assumption. Considering this particular scenario, we present a literature review addressing several important aspects related to diet and SARS-CoV-2 infection, in order to highlight the importance of diet and supplementation in prevention and management of, as well as recovery from COVID-19.

Therapist Adherence to Two Treatments for Adolescent Suicide Risk: Association to Outcomes and Role of Therapeutic Alliance

2021 ◽  
Author(s):  
Maliha Ibrahim ◽  
Suzanne Levy ◽  
Bob Gallop ◽  
Stephanie Krauthamer Ewing ◽  
Aaron Hogue ◽  
...  
Keyword(s):  
Therapeutic Alliance ◽  
Suicide Risk ◽  
Adolescent Suicide ◽  
Therapist Adherence ◽  
Adolescent Suicide Risk ◽  
Risk Association

scholarly journals Role of Omega-3 Fatty Acids in the Treatment of Depressive Disorders: A Comprehensive Meta-Analysis of Randomized Clinical Trials

PLoS ONE ◽  
2014 ◽  
Vol 9 (5) ◽  
pp. e96905 ◽  
Author(s):  
Giuseppe Grosso ◽  
Andrzej Pajak ◽  
Stefano Marventano ◽  
Sabrina Castellano ◽  
Fabio Galvano ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Clinical Trials ◽  
Depressive Disorders ◽  
Randomized Clinical Trials ◽  
Meta Analysis ◽  
Omega 3 Fatty Acids ◽  
Omega 3

Role of radiofrequency ablation in the treatment of liver metastases from colorectal cancer: Pooled analysis of randomized clinical trials.

2014 ◽  
Vol 32 (15_suppl) ◽  
pp. e14557-e14557
Author(s):  
Fabrizio Drudi ◽  
Emiliano Tamburini ◽  
Manuela Fantini ◽  
Antonio Polselli ◽  
Lucia Stocchi ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Clinical Trials ◽  
Radiofrequency Ablation ◽  
Liver Metastases ◽  
Randomized Clinical Trials ◽  
Pooled Analysis

Cognitive change and the therapeutic alliance: The role of technical and nontechnical factors in cognitive therapy.

Psychotherapy ◽  
1999 ◽  
Vol 36 (4) ◽  
pp. 320-328 ◽  
Author(s):  
Neil A. Rector ◽  
David C. Zuroff ◽  
Zindel V. Segal
Keyword(s):  
Therapeutic Alliance ◽  
Cognitive Therapy ◽  
Cognitive Change

scholarly journals Role of nab-paclitaxel in metastatic breast cancer: a meta-analysis of randomized clinical trials

Oncotarget ◽  
2017 ◽  
Vol 8 (42) ◽  
pp. 72950-72958 ◽  
Author(s):  
Yun Liu ◽  
Guoxin Ye ◽  
Dali Yan ◽  
Lei Zhang ◽  
Fan Fan ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Clinical Trials ◽  
Metastatic Breast Cancer ◽  
Randomized Clinical Trials ◽  
Meta Analysis ◽  
Metastatic Breast

scholarly journals Anemia in Chronic Kidney Disease : Role of Hypoxia Inducible Factor Stabilizer

2021 ◽  
Vol 5 (3) ◽  
pp. 395-400
Author(s):  
Emilia ◽  
Zulkhair Ali
Keyword(s):  
Chronic Kidney Disease ◽  
Clinical Trials ◽  
Randomized Clinical Trials ◽  
Hypoxia Inducible Factor ◽  
Iron Availability ◽  
Current Standard ◽  
Erythropoietin Production ◽  
Significant Harm ◽  
Erythropoietin Deficiency

A B S T R A C TAnemia contributes to increased morbidity and mortality in chronic kidney diseasepatients. The pathogenesis of anemia in these patients is multifactorial, but thecontribution of erythropoietin deficiency becomes greater as glomerular filtrationrate declines which related to decreased nephron mass. The current standard ofcare includes supplemental iron, erythropoiesis-stimulating agents (ESA), and redblood cell transfusions, although each has drawbacks. Lately, concern has arisenfollowing randomized clinical trials showing that higher hemoglobin targets and/orhigh ESA doses may cause significant harm including increasing cardiovascular andthrombotic events, and even death. Recent experimental and clinical studies showthe promising efficacy of hypoxia inducible factor (HIF) stabilizer which stimulatesendogenous erythropoietin production and enhance iron availability.

scholarly journals A partial defense of clinical equipoise

2019 ◽  
Vol 15 (2) ◽  
pp. 1-17
Author(s):  
Scott D Gelfand
Keyword(s):  
Clinical Trials ◽  
Randomized Clinical Trials ◽  
Clinical Equipoise ◽  
Best Interest ◽  
Fourth Section ◽  
Insight Into ◽  
Shed Light

In this essay, I suggest that a slightly modified version of Freedman’s formulation of the clinical equipoise requirement is justified. I begin this essay with a brief discussion of the equipoise requirement. In the second and third sections, I discuss several objections to the clinical equipoise requirement as well as two attempts to justify the equipoise requirement. In the fourth section, in order to gain some insight into what it means to say that a physician has an obligation to act in the best interest of her patient, I examine a similar obligation, namely, a parent’s obligation to act in her child’s best interest. I claim that there are several uncontroversial exceptions to this obligation, and these exceptions arise when a parent occupies a role more complex than the role of parent simpliciter. In the fifth section, I explore whether the exceptions to a parent’s obligation to act in her child’s best interest may shed light on some exceptions to a physician–researcher’s obligation to act in the best interest of her patient. These exceptions, I suggest, arise when a physician occupies a role more complex than physician simpliciter, and they ground a permission to conduct randomized clinical trials, even if doing so is not in the best interest of a physician–researcher’s patients. I furthermore claim that these exceptions provide justification for a modified formulation of the clinical equipoise requirement.

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