Health anxiety in women with early-stage breast cancer: What is the relationship to social support?

2012 ◽  
Vol 44 (2) ◽  
pp. 108-116 ◽  
Author(s):  
Shannon L. Jones ◽  
Heather D. Hadjistavropoulos ◽  
Simon B. Sherry
Keyword(s):  
Breast Cancer ◽  
Social Support ◽  
Early Stage ◽  
Health Anxiety ◽  
Early Stage Breast Cancer ◽  
The Relationship

Effects of two types of social support and education on adaptation to early-stage breast cancer

2002 ◽  
Vol 25 (6) ◽  
pp. 459-470 ◽  
Author(s):  
Nelda Samarel ◽  
Lorraine Tulman ◽  
Jacqueline Fawcett
Keyword(s):  
Breast Cancer ◽  
Social Support ◽  
Early Stage ◽  
Early Stage Breast Cancer

Impact of African ancestry on the relationship between BMI and survival in early stage breast cancer: Retrospective analysis from E5103.

2021 ◽  
Vol 39 (15_suppl) ◽  
pp. 1010-1010
Author(s):  
Tarah Jean Ballinger ◽  
Guanglong Jiang ◽  
Fei Shen ◽  
Kathy Miller ◽  
Bryan P. Schneider
Keyword(s):  
Breast Cancer ◽  
Racial Disparities ◽  
Early Stage ◽  
African Ancestry ◽  
Genetic Ancestry ◽  
Early Stage Breast Cancer ◽  
European Ancestry ◽  
A Genome ◽  
The Impact ◽  
The Relationship

1010 Background: Both Black race and obesity are associated with worse survival in early stage breast cancer. Obesity disproportionately affects Black women; however, the degree this contributes to racial disparities in breast cancer remains unclear. Prior work evaluated heterogeneous populations or used self- reported race, rather than genetic ancestry. African ancestry is associated with higher BMI and worse survival in breast cancer; however, the intersection between genetic ancestry and obesity on survival outcomes remains unknown. Methods: We analyzed data from the adjuvant trial E5103. Patients with high risk, HER2 negative breast cancer received doxorubicin/cyclophosphamide x 4, followed by weekly paclitaxel x 12, with or without bevacizumab. Genetic ancestry was determined on the 2,854 patients with available germline DNA, BMI, and outcome data using principal components from a genome-wide array. The primary objective assessed impact of BMI on DFS and OS by ancestry. Multivariate Cox proportional hazard models evaluated correlation between continuous or binary BMI and survival in African (AA) and European (EA) Americans. Results: 13.4% of patients were genetically classified as AA and 86.6% as EA. Higher continuous BMI was significantly associated with worse DFS and OS only in AAs (DFS: HR = 1.25 95% CI 1.07-1.46, p = 0.004; OS: HR = 1.38 95% CI 1.10-1.73, p = 0.005); not in EAs (DFS HR = 0.97 95% CI 0.90-1.05, p = 0.50; OS HR = 1.03 95% CI 0.93-1.14, p = 0.52). By disease subtype, BMI was associated with worse outcomes only in AAs with ER+, and not TNBC. By categorical BMI, WHO class III obesity (³ 40) significantly associated with worse DFS and OS only in AAs (DFS HR = 1.98, p = 0.010; OS HR = 2.07, p = 0.064), not in EAs (DFS HR = 0.97, p = 0.86; OS HR = 1.28, p = 0.30). Proportion of African ancestry (proAA) was associated with higher BMI and worse outcomes in the total population; however, within AAs there was no significant interaction between proAA and BMI on DFS (HR = 0.36, p = 0.06) or OS (HR = 0.38, p = 0.24). In AAs, BMI remained associated with DFS (HR = 2.78, p = 0.019), suggesting higher BMI is associated with worse DFS regardless of proAA. Coefficients for the interaction term indicate that as proAA increases the impact of BMI on outcome is lessened. Conclusions: Higher BMI is significantly associated with worse breast cancer outcomes in women of African ancestry in E5103, but not in those of European ancestry. Categorically, this association was significant only for severe obesity, indicating the relationship may depend on the degree of obesity. As proAA increased in AAs, the impact of BMI on outcome was lessened, suggesting other host factors may contribute more to obesity’s influence on outcome than genetics. Determination of the optimal populations for weight loss interventions will advance precision medicine efforts to impact racial disparities and outcomes in early stage breast cancer.

scholarly journals Perceived social support change in patients with early stage breast cancer and controls.

2013 ◽  
Vol 32 (8) ◽  
pp. 886-895 ◽  
Author(s):  
Tess Thompson ◽  
Thomas L. Rodebaugh ◽  
Maria Pérez ◽  
Mario Schootman ◽  
Donna B. Jeffe
Keyword(s):  
Breast Cancer ◽  
Social Support ◽  
Perceived Social Support ◽  
Early Stage ◽  
Early Stage Breast Cancer

Trauma History as a Predictor of Psychologic Symptoms in Women With Breast Cancer

2000 ◽  
Vol 18 (5) ◽  
pp. 1084-1084 ◽  
Author(s):  
Bonnie L. Green ◽  
Janice L. Krupnick ◽  
Julia H. Rowland ◽  
Steven A. Epstein ◽  
Patricia Stockton ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Social Support ◽  
Life Events ◽  
Early Stage ◽  
Brief Symptom Inventory ◽  
Self Report ◽  
Early Stage Breast Cancer ◽  
Hierarchical Regression ◽  
Trauma History ◽  
Functional Social Support

PURPOSE: To identify predictors of psychiatric problems in women with early-stage breast cancer. PATIENTS AND METHODS: One hundred sixty women with early-stage breast cancer were recruited from three treatment centers. They filled out self-report questionnaires, including a medical history and demographic survey, the Trauma History Questionnaire, Life Event Questionnaire, Brief Symptom Inventory, Beck Depression Inventory, and Duke-UNC Functional Social Support Questionnaire, and were evaluated using the Structured Clinical Interview for DSM-III-R. RESULTS: Hierarchical regression analyses indicated that four of five variable sets made a significant incremental contribution to outcome prediction, with 35% to 37% of the variance explained. Outcomes were predicted by demographic variables, trauma history variables, precancer psychiatric diagnosis, recent life events, and perceived social support. Cancer treatment variables did not predict outcome. CONCLUSION: The findings highlight the important roles of trauma history and recent life events in adjustment to cancer and have implications for screening and treatment.

The relationship between surgical factors and margin status after breast-conservation surgery for early stage breast cancer

2009 ◽  
Vol 197 (6) ◽  
pp. 740-746 ◽  
Author(s):  
Peter J. Lovrics ◽  
Sylvie D. Cornacchi ◽  
Forough Farrokhyar ◽  
Anna Garnett ◽  
Vicky Chen ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Early Stage ◽  
Breast Conservation ◽  
Margin Status ◽  
Early Stage Breast Cancer ◽  
Breast Conservation Surgery ◽  
Conservation Surgery ◽  
The Relationship

An exploratory study of social support, distress, and life disruption among low-income hispanic women under treatment for early stage breast cancer.

2001 ◽  
Vol 20 (1) ◽  
pp. 41-46 ◽  
Author(s):  
Susan M. Alferi ◽  
Charles S. Carver ◽  
Michael H. Antoni ◽  
Sharlene Weiss ◽  
Ron E. Durán
Keyword(s):  
Breast Cancer ◽  
Social Support ◽  
Low Income ◽  
Exploratory Study ◽  
Early Stage ◽  
Hispanic Women ◽  
Early Stage Breast Cancer

scholarly journals Social support and its implications in older, early-stage breast cancer patients in CALGB 49907 (Alliance A171301)

2015 ◽  
Vol 25 (4) ◽  
pp. 441-446 ◽  
Author(s):  
Aminah Jatoi ◽  
Hyman Muss ◽  
Jake B. Allred ◽  
Harvey J. Cohen ◽  
Karla Ballman ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Social Support ◽  
Cancer Patients ◽  
Early Stage ◽  
Early Stage Breast Cancer ◽  
Breast Cancer Patients
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