Activation of corticotropin-releasing factor receptor 2 in lateral septum negatively regulates maternal defense.

2009 ◽  
Vol 123 (2) ◽  
pp. 356-368 ◽  
Author(s):  
Kimberly L. D'Anna ◽  
Stephen C. Gammie
Keyword(s):  
Corticotropin Releasing Factor ◽  
Lateral Septum ◽  
Maternal Defense

scholarly journals Maternal defense is modulated by beta adrenergic receptors in lateral septum in mice.

2011 ◽  
Vol 125 (3) ◽  
pp. 434-445 ◽  
Author(s):  
Melissa-Ann L. Scotti ◽  
Grace Lee ◽  
Stephen C. Gammie
Keyword(s):  
Adrenergic Receptors ◽  
Lateral Septum ◽  
Beta Adrenergic Receptors ◽  
Beta Adrenergic ◽  
Maternal Defense

Intermittent access to sucrose increases sucrose-licking activity and attenuates restraint stress-induced activation of the lateral septum

2010 ◽  
Vol 298 (5) ◽  
pp. R1383-R1398 ◽  
Author(s):  
Jessica Martin ◽  
Elena Timofeeva
Keyword(s):  
Stress Response ◽  
Restraint Stress ◽  
Food Restriction ◽  
Corticotropin Releasing Factor ◽  
Lateral Septum ◽  
Sucrose Consumption ◽  
Rat Models ◽  
Intermittent Access ◽  
Factor Type

Intermittent access to palatable food can attenuate anorectic and hormonal responses to stress in rats. The neuronal mechanisms of modulation of stress response by diets are not fully understood. The present study was conducted to create rat models with intermittent access to sucrose that demonstrate resistance to stress-induced hypophagia, to study the pattern of sucrose consumption by these rat models, and to investigate in which brain structures intermittent sucrose regimens modify stress-induced neuronal activation. The obtained results demonstrate that 6-wk intermittent access to sucrose without food restriction (4 day/wk ad libitum access to sucrose in addition to chow, and following 3 day/wk exclusive feeding of chow; SIA rats) and combined with food restriction (4 day/wk access to chow and sucrose restricted to 2 h/day, and following 3 days/wk on unrestricted chow; SIR rats) increased sucrose-licking activity. The alterations in the rats' feeding behavior were accompanied by a resistance of their body weight gain and food intake to 1-h restraint stress applied once per week. The chronic intermittent sucrose consumption significantly lowered, in the SIA and SIR rats, the levels of expression of corticotropin-releasing factor type 2 receptor and restraint stress-induced expression of c- fos mRNA in the medioventral part of the lateral septum. Conversely, the levels of the corticotropin-releasing factor type 2 receptor transcript in the ventromedial hypothalamic nucleus were decreased only in the food-restricted SIR rats. The lower stress-induced neuronal activation in the medioventral part of the lateral septum may contribute to the attenuated anorectic stress response in the rats maintained on intermittent sucrose regimens.

Corticotropin releasing factor-containing afferents to the lateral septum of the rat brain

1988 ◽  
Vol 270 (3) ◽  
pp. 404-415 ◽  
Author(s):  
Masahiro Sakanaka ◽  
Sumiko Magari ◽  
Tamotsu Shibasaki ◽  
Karl Lederis
Keyword(s):  
Rat Brain ◽  
Corticotropin Releasing Factor ◽  
Lateral Septum
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