Differential deficit in executive control in euthymic bipolar disorder.

2009 ◽  
Vol 118 (1) ◽  
pp. 146-160 ◽  
Author(s):  
Jill Maria Thompson ◽  
John M. Gray ◽  
John R. Crawford ◽  
John H. Hughes ◽  
Allan H. Young ◽  
...  
Keyword(s):  
Bipolar Disorder ◽  
Executive Control ◽  
Differential Deficit

Performance monitoring and executive control of attention in euthymic bipolar disorder: Employing the CPT-AX paradigm

2013 ◽  
Vol 210 (2) ◽  
pp. 457-464 ◽  
Author(s):  
Lucy J. Robinson ◽  
Jill M. Thompson ◽  
Peter Gallagher ◽  
John M. Gray ◽  
Allan H. Young ◽  
...  
Keyword(s):  
Bipolar Disorder ◽  
Executive Control ◽  
Performance Monitoring

scholarly journals Transdiagnostic Prediction of Affective, Cognitive, and Social Function Through Brain Reward Anticipation in Schizophrenia, Bipolar Disorder, Major Depression, and Autism Spectrum Diagnoses

2019 ◽  
Vol 46 (3) ◽  
pp. 592-602 ◽  
Author(s):  
Kristina Schwarz ◽  
Carolin Moessnang ◽  
Janina I Schweiger ◽  
Sarah Baumeister ◽  
Michael M Plichta ◽  
...  
Keyword(s):  
Bipolar Disorder ◽  
Social Functioning ◽  
Executive Control ◽  
Autism Spectrum ◽  
Functional Responses ◽  
Reward Anticipation ◽  
Brain Responses ◽  
Extensive Test ◽  
Reward Expectancy ◽  
Reward Network

Abstract The relationship between transdiagnostic, dimensional, and categorical approaches to psychiatric nosology is under intense debate. To inform this discussion, we studied neural systems linked to reward anticipation across a range of disorders and behavioral dimensions. We assessed brain responses to reward expectancy in a large sample of 221 participants, including patients with schizophrenia (SZ; n = 27), bipolar disorder (BP; n = 28), major depressive disorder (MD; n = 31), autism spectrum disorder (ASD; n = 25), and healthy controls (n = 110). We also characterized all subjects with an extensive test battery from which a cognitive, affective, and social functioning factor was constructed. These factors were subsequently related to functional responses in the ventral striatum (vST) and neural networks linked to it. We found that blunted vST responses were present in SZ, BP, and ASD but not in MD. Activation within the vST predicted individual differences in affective, cognitive, and social functioning across diagnostic boundaries. Network alterations extended beyond the reward network to include regions implicated in executive control. We further confirmed the robustness of our results in various control analyses. Our findings suggest that altered brain responses during reward anticipation show transdiagnostic alterations that can be mapped onto dimensional measures of functioning. They also highlight the role of executive control of reward and salience signaling in the disorders we study and show the power of systems-level neuroscience to account for clinically relevant behaviors.

Common and disease-specific dysfunctions of brain systems underlying attentional and executive control in schizophrenia and bipolar disorder

2013 ◽  
Vol 264 (6) ◽  
pp. 517-532 ◽  
Author(s):  
Tobias Melcher ◽  
Sarah Wolter ◽  
Stefanie Falck ◽  
Eva Wild ◽  
Florian Wild ◽  
...  
Keyword(s):  
Bipolar Disorder ◽  
Executive Control ◽  
Disease Specific

Functional magnetic resonance imaging of executive control in bipolar disorder

Neuroreport ◽  
2006 ◽  
Vol 17 (11) ◽  
pp. 1085-1089 ◽  
Author(s):  
Robert M. Roth ◽  
Nancy S. Koven ◽  
John J. Randolph ◽  
Laura A. Flashman ◽  
Heather S. Pixley ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Bipolar Disorder ◽  
Magnetic Resonance ◽  
Functional Magnetic Resonance Imaging ◽  
Executive Control ◽  
Functional Magnetic Resonance ◽  
Resonance Imaging

Navigating Tx of Bipolar Disorder in Pregnancy

Ob Gyn News ◽  
2005 ◽  
Vol 40 (3) ◽  
pp. 11
Author(s):  
DIANA MAHONEY
Keyword(s):  
Bipolar Disorder ◽  
In Pregnancy

Valproate May Help Child With Bipolar Disorder

2005 ◽  
Vol 39 (5) ◽  
pp. 26
Author(s):  
Jeff Evans
Keyword(s):  
Bipolar Disorder

Bipolar Disorder

2017 ◽  
Author(s):  
Robert P. Reiser ◽  
Larry W. Thompson ◽  
Sheri L. Johnson ◽  
Trisha Suppes
Keyword(s):  
Bipolar Disorder
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