Osseous system.

2011 ◽  
pp. 156-170
Author(s):  
James B. Alexander
Keyword(s):  
Endocrinology ◽  
1944 ◽  
Vol 34 (5) ◽  
pp. 305-310 ◽  
Author(s):  
HERMANN BECKS ◽  
MIRIAM E. SIMPSON ◽  
CHOH HAO LI ◽  
HERBERT M. EVANS

2009 ◽  
pp. 107-122
Author(s):  
John Fleming
Keyword(s):  

2006 ◽  
Vol 16 (1-4) ◽  
pp. 19-27
Author(s):  
BARBARA NOWIŃSKA ◽  
ILONA KACZMARCZYK-SEDLAK ◽  
WALDEMAR JANIEC ◽  
LESZEK ŚLIWIŃSKI ◽  
URSZULA CEGIEŁA ◽  
...  

Blood ◽  
1949 ◽  
Vol 4 (9) ◽  
pp. 1049-1067 ◽  
Author(s):  
MICHAEL A. RUBINSTEIN

Abstract The conventional points in the differential diagnosis between myeloma and leukemia have been discussed. Evidence has been brought to show that these points of distinction cannot be regarded as being of fundamental nature. Instances are abstracted where cases of multiple myeloma show the various characteristics of leukemia and vice versa. 1. Leukemic features in myeloma have been shown in: a. diffuse infiltration in multiple myeloma without circumscribed tumor formation and without any gross bone destruction; b. extraskeletal visceral myelomatous spread involving the kidney, spleen, lymph nodes, etc.; c. invasion of peripheral blood in myeloma—occasional myeloma cells (corresponding to the aleukemic forms of leukemia) may frequently be found in concentrated smears, even though they may be missed on routine examination; however, massive invasion of peripheral blood is rare; d. increased uric acid content of the blood and elevated basal metabolism, characteristic of leukemia, frequently seen also in myeloma; e. occurrence of myeloma in youth; f. symptomatology of multiple myeloma at times not referable to the osseous system. 2. Myeloma features in leukemia have been shown in: a. skeletal involvement in leukemia; b. very rare medullary forms of leukemia (without visceral involvement); c. occurrence of Bence-Jones proteinuria or d. hyperproteinemia with hyperglobulinemia in rare cases of leukemia; e. instances when the symptomatology of leukemia was referable to the osseous system. 3. Coexistence of multiple myeloma and leukemia is reviewed from the literature, and a case is reported of extensive mixed lymphocytic and plasma cell infiltration. In conclusion, the difference between myeloma and leukemia, as far as the listed conventional distinguishing features are concerned, is merely one of incidence: what is rare in one disease, is common in the other, and vice versa. Multiple myeloma is in all probability a leukemia of plasma cells.


Endocrinology ◽  
1944 ◽  
Vol 34 (5) ◽  
pp. 311-316 ◽  
Author(s):  
HERMANN BECKS ◽  
MIRIAM E. SIMPSON ◽  
WALTER MARX ◽  
CHOH HAO LI ◽  
HERBERT M. EVANS

1898 ◽  
Vol 44 (184) ◽  
pp. 101-104
Author(s):  
J. F. Briscoe

The object of this communication is to draw from the members of the Association the modern treatment of fractures as adopted in institutions for the insane. It is obvious that the various plans, as practised in hospitals, must be considerably modified in asylums. For instance, to strap and bandage a case of fractured ribs, secundum artem, taxes any medical officer, unless the patient is quietly disposed and clean in his habits. However, with skill and a fairly docile patient, there should be little difficulty in the management of ordinary fractures of the bones below the elbows and the knees. From time to time one reads of cases of fractures of the ribs occurring in asylums, remarkable autopsies being recorded. It is difficult sometimes to give a correct history of their causation, and, in consequence, much opprobrium has been unjustly cast on asylum officials. It is believed by not a few that there is a peculiar affection of the ribs in the insane causing them to fracture readily. It is said, too, that it is common in general paralysis. Dr. Christian has stated in the Journal of Mental Science, January, 1886, that he is decidedly opposed to the idea that general paralytics are more liable to fracture of the bones. He gives 250 cases, and says, “I can assure you, gentlemen, I have not come across a single case of fracture among them.” But no figures of the kind can be relied upon unless verified by post-mortem examination. It is not uncommon to find in the mortuaries of ordinary hospitals and asylums, and in the dissecting-room, specimens of fractured ribs, the causation of which is unaccounted for. With our present pathological knowledge of the osseous system we must withhold our verdict.


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